Sentences with phrase «of epilepsy drugs»

«Running prevents postnatal side effects of epilepsy drugs in mice.»

Britain's competition watchdog has fined Pfizer a record 84.2 million pounds ($ 107 million) for its role in ramping up the cost of an epilepsy drug by as much as 2,600 %.

2018-04-06: Two lots of the epilepsy drug Primidone recalled because of high levels of lead, which may pose serious health risks

Volunteers who ate veggies grown in wastewater had higher (but still safe) levels of an epilepsy drug in their urine, compared with subjects who ate freshwater - grown veggies.

Not exact matches

It is now possible to treat epilepsy and schizophrenia (madness) using a herbal drug discovered by a Nigerian Scholar of Pharmacology and Toxicology of Kaduna state...

The study — led by James Murrough, associate professor of psychiatry and director of the Mood and Anxiety Disorders Program at Mount Sinai — chose the epilepsy drug ezogabine, which was given to 18 patients in a pilot trial.

It is a minimally invasive procedure that is proving to be a very effective treatment for people with medial temporal lobe epilepsy (MTLE), a common form of drug - resistant epilepsy.

Intractable epilepsy, number of antiepileptic drugs used, and the number of seizures were similar in all groups.

Nearly 30 percent of epilepsy patients are resistant to drug therapy, so they have the option of surgery to remove their seizure onset zones.

But new research holds out hope that drugs developed to treat other neurological problems — notably epilepsy — could rein in the compulsive and blind drive to eat at the core of the disorder.

Administering the epilepsy drug retigabine opened the potassium channels and counteracted much of the toxin's effects, raising hopes of a treatment for these bites.

A technique that involves genetically engineering brain cells so that they fire in the presence of certain drugs has been used to treat epilepsy in rats, and it could soon be tested in humans.

In a recent trial of 225 patients, completed in September 2016, participants who took the drug (along with their other epilepsy medications) reduced their nonstop seizures by 42 percent, compared with 17 percent for those taking a placebo.

As many as three million people in the U.S. live with epilepsy, and more than 30 percent of them receive inadequate relief from medication, a number that persists despite the introduction of more than a dozen new antiepileptic drugs since 1990.

The first effective drug for epilepsy, potassium bromide, was introduced in the 1850s and works by inhibiting the excitability of neurons.

A 2013 joint report from epilepsy research organizations explained that «because the marketplace is already awash with [antiseizure drugs], many pharmaceutical companies now refrain from the expensive enterprise of developing new compounds.»

Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

In addition, the creation of a zebrafish model for CHD2 encephalopathy may facilitate the discovery of new drugs that can treat patients with this form of epilepsy.

«Some psychotic disorders may be induced by drugs designed to combat effects of epilepsy.»

The discovery opens the possibility of designing new types of drugs against conditions such as epilepsy.

The study examined how many babies were diagnosed with epilepsy and how many are on regular antiepileptic drug treatment at two and four to eight years of age.

Even if a lesser severity of perinatal asphyxia is accounted for, cooling therapy has increased the number of healthy survivors and there are very few children with epilepsy needing drug treatment.

Approximately one third of people with epilepsy still experience seizures even when receiving treatment, and currently available anti-epileptic drugs often have side effects such as tiredness and dizziness.

At two years, seven per cent of the children had an epilepsy diagnosis, however, far fewer, only two per cent, were on regular antiepileptic drugs.

I have epilepsy and experienced many of the ADRs my drugs cause.

So far the CGRP drugs work better at prevention than any of the borrowed heart or epilepsy drugs and have far fewer side effects.

The DNA Lounge can not sell any of these compounds as smart drugs because most can only be legally prescribed by doctors, and even then only for other purposes: L - Dopa for Parkinson's disease, phenytoin for epilepsy, propanolol for certain heart conditions.

If people with focal epilepsy don't respond well to standard drugs, they are often offered surgery to remove the part of the brain where the problems start.

A technique that involves genetically engineering brain cells so that they fire in the presence of certain drugs has been used to treat an epilepsy - like condition in rats, and it could soon be trialled in humans.

Two newer epilepsy drugs may not harm the thinking skills or IQs of school - aged children whose mothers took them while pregnant — but an older drug is linked to cognitive problems in children, especially if their mothers took high doses — according to new research from The University of Manchester.

Participants were randomized into four different interventions that would analyze how effectively an acupuncture technique known as electroacupuncture — in which embedded needles deliver weak electrical currents — reduces incidents of hot flashes as compared to the epilepsy drug gabapentin, which was previously shown to be effective in reducing hot flashes for these patients.

«Unfortunately, there are no preventive therapies for any common disorder of the human nervous system — Alzheimer's, Parkinson's, schizophrenia, epilepsy — with the exception of blood pressure - lowering drugs to reduce the likelihood of stroke,» said study author James O. McNamara, M.D., professor of neurobiology at Duke Medicine.

In utero exposure to the epilepsy drug VPA appears to elevate the risk to babies of developing an autism spectrum disorder.

«Expectant mothers with epilepsy may need to continue their drug regime during pregnancy; this research may give them some reassurance that — provided they are prescribed topirimate and levetiracetam — they will a statistically good chance of normal, healthy development in their children,» concluded Dr Bromley.

Babies whose mothers take the epilepsy drug valporic acid (VPA) during pregnancy, for example, appear to have an elevated risk of developing an autism spectrum disorder.

«From our past research, we know the ketogenic diet is effective in approximately one - third of adults with epilepsy who are resistant to traditional anti-seizure drugs,» says Mackenzie C. Cervenka, M.D., associate professor of neurology and director of the Adult Epilepsy Diet Center at the Johns Hopkins University School of Medicine.

If the drug stopped the genetically altered mice from becoming epileptic, this genetic approach would prove that inhibiting TrkB prevents the onset of epilepsy.

The ability to temporarily disable or stimulate parts of the brain with the flick of a switch has led researchers to explore DBS in the treatment of several other conditions, including epilepsy, depression, obesity and drug addiction.

While there is no known trigger behind seizures in people with epilepsy, Dr. Kuebler and his lab are using their drug - screening technique to investigate potential metabolic causes — using genetically modified, seizure - prone flies (a family of Drosophila flies called Bang - sensitive paralytic mutants).

The precise understanding of the mode of action is thus the basis for developing specific drugs for the treatment of epilepsy and cardiac arrhythmias.

A zebrafish model of Dravet syndrome, a severe form of pediatric epilepsy, may help scientists quickly find drugs for the devastating disease.

The way to do so occurred to Olaf Blanke — a neurologist and cognitive neuroscientist at the Brain - Mind Institute, part of the École Polytechnique Fédérale de Lausanne in Switzerland — a decade ago while he worked with an epilepsy patient, a 43 - year - old woman with drug - resistant seizures who had to be treated with surgery.

Topamax, an epilepsy drug from Ortho - McNeil Pharmaceutical, has proven extremely effective on migraines in clinical trials: Half of all patients have reported a 50 percent reduction in the frequency of migraines, and more than a quarter have a reported 75 percent reduction.

Diseases such as epilepsy, neuropathic pain, anxiety, depression, drug addiction and Alzheimer's are all associated with changes in the excitability of brain neurons.

Dravet syndrome is a severe form of pediatric epilepsy characterized by frequent daily drug - resistant seizures and developmental delays.

Now, a study in the journal Brain describes what could be considered a direct «aquarium - to - bedside» approach, taking a drug discovered in a genetic zebrafish model of epilepsy and testing it, with promising results, in a small number of children with the disease.

This technique, known as «responsive neurostimulation» (RNS), has proved effective for epilepsy and an existing system has been approved by the U.S. Food and Drug Administration for treating partial onset seizures (which affect only part of the brain).

While the study is limited to a drug used extensively in epilepsy and psychiatry, the implications of such findings extend beyond this particular drug, indicating that FDA standards for bioequivalence are appropriate.

AES, the American Academy of Neurology and other professional societies had opposed patients substituting antiepileptic generics for people with epilepsy without consent of the physician or patient out of concern that the U.S. Food and Drug Administration (FDA) was allowing room for too much variability across formulations.

Lamotrigine, a widely used drug for the treatment of epilepsy, is an ideal drug for this assessment, says Privitera, particularly because it has also been the subject of the noted problems with generic switches and complaints to the FDA.