Nearly 30
percent of epilepsy patients are resistant to drug therapy, so they have the option of surgery to remove their seizure onset zones.
Scientists at the University of Wisconsin and UCLA conducted the study, which implanted electrodes deep into the
craniums of epilepsy patients to monitor their brain activity during seizures.
Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a
subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.
The scientists found the same changes in deltaFosB and calbindin levels in the hippocampus of Alzheimer's disease patients and in the temporal
lobe of epilepsy patients.
Sleep scientists at New York University have been enlisting the
help of epilepsy patients undergoing seizure diagnosis, who already have electrodes inserted into their brains.
«Research shows that seizures typically improve in about 50 percent
of epilepsy patients who follow the classic ketogenic diet.