Sentences with phrase «of epithelial»

Cancer — High Prevalence in California Sea Lions A specific cancer of epithelial origin was first diagnosed in California sea lions at The Marine Mammal Center in 1979.

A specific cancer of epithelial origin was first diagnosed in California sea lions at The Marine Mammal Center in 1979.

One of the greatest benefits of zinc is in the maintenance and production of epithelial tissue.

Epidermoid and dermoid cysts result from inclusion of epithelial components of embryonal tissue at the time of closure of the neural tube.

It is a tumor made up of the epithelial cells that line the bladder wall.

The cornea is 5 - 7 cells thick and is made of epithelial cells, rather like the skin.

To date, there is no definitive evidence that a sequential multistep process, considered the hallmark of epithelial carcinogenesis (30), is operational in the transformation of mesenchymal cells.

The peak incidence of epithelial tumors is between 4 to 15 years.

Radiation therapy may cause severe damage to normally growing cellular populations, like those of epithelial (outer layer of the skin) and skin tissues.

Pieces may break off the shaggy surface of epithelial tumors and implant on the inner wall of the abdomen where they will continue to grow..

a malignant growth made up of epithelial cells tending to infiltrate surrounding tissues and gives rise to metastases (spreading).

Hepatocellular carcinoma is a malignant tumor of the epithelial cells of the liver.

Tumors may also be classified by the type of epithelial growth because this influences the probability of recurrence.

Dietary fat intake and risk of epithelial ovarian cancer.

The tissue of your small intestine is made up of epithelial cells held together by several junctions, the most important being the tight junctions.

Functions of epithelial cells include secretion, selective absorption, protection, trans - cellular transport and selective permeability.

Journal of Epithelial Biology & Pharmacology, 5 (Suppl 1 - M7), 47 — 54.

While vitamin A is best known for its vital role in vision, the retinoid forms of this vitamin also participate in physiological activities related to the immune system, inflammatory system, maintenance of epithelial and mucosal tissues, growth, reproduction, bone development, creation of red blood cells, and production of spermatozoa (male reproductive cells).

Stress has been shown to reduce the integrity of the epithelial cells that the important semipermeable membrane is comprised of.

The group who consumed soy protein had significant increases in the proliferation of epithelial cells in the breasts.

Yet in 1996 researchers found that women consuming soy protein isolate had an increased incidence of epithelial hyperplasia, a condition that presages malignancies.45 A year later, dietary genistein was found to stimulate breast cells to enter the cell cycle, a discovery that led the study authors to conclude that women should not consume soy products to prevent breast cancer.46

We have previously reported that these KD cells are partially transformed as evidenced by the disruption of epithelial polarity and morphological differentiation in the 3D IrECM (He et al., 2008).

During the culture of these cells, we noticed a change in cell morphology from the cobble stone - like shape typical of epithelial cells to a more spindle - like and scattered appearance (Figure 2A, lower panel), indicating these cells may be undergoing EMT.

While found in some mammary cells prior to pregnancy, the activated form of STAT5 is detected in the great majority of epithelial mammary cells, and at increased levels, during pregnancy and lactation (Liu et al., 1995; Wagner and Rui, 2008).

In a mouse model of skin wound healing (regeneration), we demonstrated the unique expression of β3 - integrin in PHD2 - deficient keratinocytes, which improved healing through the enhanced migration of the epithelial layers (Kalucka et al., Mol.

This lining consists of a layer of epithelial cells that come together to form a barrier that is impenetrable to the nanoparticles, thereby necessitating the use of injections to be an effective form of treatment.

Leveraging the phylogenetic position of Cnidaria and the accessibility of Nematostella tentacle tubes to optical observation and experimental manipulation (see Video 2), we will define the biochemical and mechanical cues that drive the morphogenesis of epithelial tubes in a broad evolutionary context.

The ΔN isoforms of p63 may also serve as stem cell markers in a variety of epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].

Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, Fotheringham S, Wulf G, English J, Kirschmeier PT, Velculescu VE, Paweletz CP, Mills GB, Livingston DM, Brugge JS, Matulonis UA, Drapkin R.: Establishment of patient - derived tumor xenograft models of epithelial ovarian cancer for pre-clinical evaluation of novel therapeutics.

Our final review article, from the labs of Maximilian Boesch (Kantonsspital St. Gallen, Switzerland) and Andreas Seeber (Medical University of Innsbruck, Austria), provides an update on the role of epithelial cell adhesion molecule (EpCAM) in cancer stem cells (CSCs) and the epithelial ‐ to ‐ mesenchymal transition (EMT) in colorectal cancer (CRC).

In a wide range of epithelial tissues such as kidney tubules or breast acini, cells organize into bidimensional monolayers experiencing an out - of - plane curvature.

Past projects: Our research has previously focused on finding novel ways to stimulate chloride and water secretion of epithelial cells in understanding cystic fibrosis (CF).

Conversely, high curvature is identified as the inducer of frequent cell detachments at the front edge, a phenotype reminiscent of the Epithelial - Mesenchymal Transition.

B. anthracis secretes lethal toxin, which contributes to barrier disruption via interference of epithelial, endothelial and immune cell function [5].

8) Korinek, V., Barker, N., Moerer, P., van Donselaar, E., Huls, G., Peters, P.J. and Clevers, H. Depletion of epithelial stem - cell compartments in the small intestine of mice lacking Tcf - 4.

This work highlights the importance of specialized apical pole disassembly for the repolarization of epithelial cells initiating migration.

Akanksha Jain: Molecular, cellular and mechanical basis of epithelial morphogenesis during Tribolium embryogenesis

In this paper, we study the development and migration of epithelial tissues on glass wires of well - defined radii varying from less than 1 µm up to 85 µm.

The microscope image of the dorsal closure of a fly embryo shows alter - nating stripes of epithelial cells with aligned microtubule bundles (green) and epithelial cells treated with a microtubule - destroying drug (blue).

Saliva is often collected for genotyping studies but is rarely used to examine DNA methylation because the proportion of epithelial cells and leukocytes varies extensively between individuals.

SCNN1A (sodium channel, non-voltage-gated 1 alpha), also known as ENaCA (epithelial Na (+) channel subunit alpha) or amiloride - sensitive sodium channel subunit alpha, is the alpha subunit of the epithelial Na (+) channel (ENaC).

Expression of epithelial - mesenchymal transition (EMT)- associated markers in the total cell population and the cycling hypoxia - selected subpopulation.

It turns out that lots of epithelial tumors (carcinomas) have insulin receptors too.

Using a qRT - PCR - based method, we found dramatic decreases of epithelial miRNAs (miR200c and miR205) in the F3 subpopulations compared with the parental breast cancer cell lines (Figure 6e).

In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organisms.

Work in our group is aimed to understand the cellular, molecular and genetic mechanisms that control the establishment and maintenance of epithelial cell polarity.

Scientists taking a close look at how a dangerous food - borne bacterium invades the gut have identified a new culprit, a molecule that normally helps hold the intestinal lining and other sheets of epithelial cells together.

Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial - Mesenchymal Transition.

This plasticity carries the hallmarks of epithelial to mesenchymal transition (EMT) and is the subject of intense research in our lab and worldwide.

Membrane lipidome of an epithelial cell line.