Sentences with phrase «of epithelial cell»

The ΔN isoforms of p63 may also serve as stem cell markers in a variety of epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].

Our final review article, from the labs of Maximilian Boesch (Kantonsspital St. Gallen, Switzerland) and Andreas Seeber (Medical University of Innsbruck, Austria), provides an update on the role of epithelial cell adhesion molecule (EpCAM) in cancer stem cells (CSCs) and the epithelial ‐ to ‐ mesenchymal transition (EMT) in colorectal cancer (CRC).

Work in our group is aimed to understand the cellular, molecular and genetic mechanisms that control the establishment and maintenance of epithelial cell polarity.

Membrane lipidome of an epithelial cell line.

A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity.

«The inflammasome in turn activates the enzyme caspase - 1, which then produces two proteins (IL - 1β and IL - 18) that play important roles in the GI tract, including activation of immune cells, induction of antimicrobial peptides, and regulation of epithelial cell proliferation.»

Heaton et al. now report that a special type of epithelial cell in the lungs of mice — called club cells — survive influenza infection.

The intestine is made up of epithelial cells.

They concluded from that evidence that these specialized RNAs were coming from two types of epithelial cells that line the GI tract.

The invasion of epithelial cells and immune cells are controlled by two separate gene clusters called Salmonella Pathogenicity Islands 1 and 2 (SPI1, SPI2) respectively.

genes, the team has shown that B. theta helps guide the normal development and functioning of the intestines — including the growth of blood vessels, the proper turnover of epithelial cells, and the marshaling of components of the immune system needed to keep less well behaved bacteria at bay.

In a previous study, Professor Schmidt - Ott and his team discovered that it regulates the differentiation of epithelial cells — they line the cavities and surfaces of structures throughout the body — in the mouse embryo.

Their embryos had more profound defects than were seen in the Esrp1 - null mice, including craniofacial and forelimb defects, and the complete absence of lungs and salivary glands — two organs made up largely of epithelial cells.

She and her group had studied the nature and function of epithelial cells, the gut - lining cells that come into contact with breast milk in nursing infants.

«And those are the types of patients, who potentially would eventually go to the intensive care unit, that we think could be treated early in infection with Accolate or Singulair to prevent infection of these epithelial cells and prevent lethal infection.»

«Normally, botulinum neurotoxin molecules are too large to break through this tight junction of epithelial cells,» Jin said.

«The first thing that needs to happen for wound healing is to activate the migration of epithelial cells,» Oudhoff says.

IFN - I triggers many different immune responses, but can also speed up the replacement of epithelial cells.

The images show how a growth factor caused cells to change forms and regroup from tight packs of epithelial cells to more mobile, loose arrays of mesenchymal cells — information useful for studying cancer and wound healing.

These structures were further examined by tissue - level and immunohistochemical tools, revealing ducts with «excessive layers» of epithelial cells, potentially pre-cancerous lesions that were «highly proliferative» compared to normal ducts, they add.

The tubes enclose hollow spaces called lumens and are primarily composed of a single or multiple layers of epithelial cells.

The human airway is lined with two kinds of epithelial cells — those that possess hairlike fringes called cilia and those that don't.

Studies have found a high - fat diet destroys gut microbiota, reduces the production of epithelial cells lining the intestine and causes gut bacteria to invade intestinal epithelial cells.

In the new study, the researchers explored the role of cell shape in two vastly different types of epithelial cells — human bronchial epithelial cells grown in the lab and cells within the living embryo of the fruit fly — and observed them as they matured over time.

«The new protein plays a key role in the formation of adherens junctions of epithelial cells, and Listeria uses it for its own infectious process.»

Protocols to grow organoids as polarized monolayers of epithelial cells on membranes or filters are already in place for the intestine, gall bladder, liver and pancreatic ducts (21).

Scientists taking a close look at how a dangerous food - borne bacterium invades the gut have identified a new culprit, a molecule that normally helps hold the intestinal lining and other sheets of epithelial cells together.

Saliva is often collected for genotyping studies but is rarely used to examine DNA methylation because the proportion of epithelial cells and leukocytes varies extensively between individuals.

The microscope image of the dorsal closure of a fly embryo shows alter - nating stripes of epithelial cells with aligned microtubule bundles (green) and epithelial cells treated with a microtubule - destroying drug (blue).

This work highlights the importance of specialized apical pole disassembly for the repolarization of epithelial cells initiating migration.

Past projects: Our research has previously focused on finding novel ways to stimulate chloride and water secretion of epithelial cells in understanding cystic fibrosis (CF).

This lining consists of a layer of epithelial cells that come together to form a barrier that is impenetrable to the nanoparticles, thereby necessitating the use of injections to be an effective form of treatment.

During the culture of these cells, we noticed a change in cell morphology from the cobble stone - like shape typical of epithelial cells to a more spindle - like and scattered appearance (Figure 2A, lower panel), indicating these cells may be undergoing EMT.

The group who consumed soy protein had significant increases in the proliferation of epithelial cells in the breasts.

Stress has been shown to reduce the integrity of the epithelial cells that the important semipermeable membrane is comprised of.

Functions of epithelial cells include secretion, selective absorption, protection, trans - cellular transport and selective permeability.

The tissue of your small intestine is made up of epithelial cells held together by several junctions, the most important being the tight junctions.

Hepatocellular carcinoma is a malignant tumor of the epithelial cells of the liver.

a malignant growth made up of epithelial cells tending to infiltrate surrounding tissues and gives rise to metastases (spreading).

The cornea is 5 - 7 cells thick and is made of epithelial cells, rather like the skin.

It is a tumor made up of the epithelial cells that line the bladder wall.

Not exact matches

A piece of Wicht's bedsheet the night she was found dead contained another man's sperm, along with a man's epithelial cells.

The strict definition of celiac disease — positive antibodies to gliadin, intestinal endomysium, and tissue transglutaminase, together with the presence of HLA - DQ2 or HLA - DQ8 genes and an intestinal biopsy that shows at least 20 - 25 CD3 cells per 100 epithelial cells — will account for about 75 - 80 % of all those sensitive to gluten.

These growth modulators are produced either by the epithelial cells of the mammary gland or by activated macrophages, lymphocytes (mainly T cells), or neutrophils in the milk.

Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated from human breastmilk in mammary epithelial cell culture.

This process includes the removal of the milk - producing epithelial cells, whereby the alveolar epithelium undergoes apoptosis and is replaced with adipocytes.

In the first half of pregnancy secretory differentiation (the differentiation of alveolar epithelial cells into milk - secreting cells), ductal branching and lobular formation of the breast (mammogenesis) occur.

Milk sodium concentration is a marker of tight junction closure between mammary epithelial cells; with the onset of secretory activation (stage II lactogenesis) milk sodium concentrations decrease sharply as potassium concentrations increase [14].

About 3 — 8 % of human milk fat globules contain mammary epithelial cell cytoplasmic remnants, including RNA, captured during milk fat globule formation and secretion [9].

However, there is an intriguing workaround — human milk secreted during lactation is a rich source of mammary epithelial cell RNA.