Title: Effect of a single dose
of escitalopram on serotonin concentration in the non-human and human primate brain Author: M. Nord et al..
«Our study shows that genotyping of CYP2C19 could be of considerable clinical value in individualising doses
of escitalopram so that a better all - round antidepressive effect could be achieved for the patients,» says Professor Magnus Ingelman - Sundberg at Karolinska Institutet's Department of Physiology and Pharmacology who led the study together with Professor Espen Molden.
In the randomised study, all patients with social anxiety disorder were treated with the same dosage
of escitalopram for nine weeks, but only one group was correctly informed about the drug and its effectiveness.
Not exact matches
In a study published in EBioMedicine, a group
of researchers at Uppsala University's Department
of Psychology, Sweden, now demonstrate considerably better effects
of the SSRI
escitalopram when given with correct as compared to incorrect verbal information.
Pharmaceutical treatment
of depression commonly makes use
of selective serotonin reuptake inhibitors (SSRIs)
of which
escitalopram is the most frequently administered clinically.
However,
escitalopram therapy is currently limited by the fact that some patients do not respond well to the drug, while others develop adverse reactions requiring discontinuation
of treatment.
Overall, one third
of the 2,087 study participants achieved
escitalopram blood levels that were either too high or too low.
Title: An inflammatory biomarker as a differential predictor
of outcome
of depression treatment with
escitalopram and nortriptyline Author: R. Uher et al..
Rasenick and colleagues further analyzed
escitalopram to investigate the properties
of antidepressants that preferentially accumulate in lipid rafts.
Although both groups exhibited improvement in the severity
of depression, larger reductions were seen in individuals taking
escitalopram as well as practicing tai chi, a kind
of exercise that's gentle enough for older people.
In one study, people prescribed
escitalopram (Lexapro / Cipralex) were given a supplement
of 1000 mg curcumin or placebo.
In the analysis
of 12 different drugs, two came out on top as the most effective and best tolerated as first - line treatments: sertraline (Zoloft) and
escitalopram (Lexapro).
«The women on
escitalopram were much more likely to [think] their treatment was helpful,» says the lead researcher, Ellen W. Freeman, PhD, a professor
of ob - gyn at the University
of Pennsylvania School
of Medicine, in Philadelphia.
The antidepressant Lexapro (
escitalopram) may reduce the frequency and severity
of hot flashes, the bouts
of sweating and overheating that are an uncomfortable fact
of life for many menopausal women, a new government - funded study suggests.
Compared with placebo, treatment
of depressed systolic heart failure patients with
escitalopram will result in a significant improvement in symptoms
of depression at six months, when measured using the Hamilton Depression Rating Scale.
Compared with placebo, treatment
of depressed systolic heart failure patients with
escitalopram will result in a significant improvement in symptoms
of depression at six months, when measured using the Cardiac Depression Scale.
Continued
escitalopram reduces risk
of relapse in people with generalised social anxiety disorder
The improvement in depression
of heart failure patients treated with
escitalopram will parallel improved autonomic function, as principally measured by HRV sympatho - vagal balance in the frequency domain.