Sentences with phrase «of ezetimibe»

Hearings in January revealed that the release of negative results of a clinical trial of ezetimibe had been delayed.

Not exact matches

Instead, ezetimibe blocks dietary cholesterol absorption in the gut by inhibiting the NPC1L1 protein, perhaps approximating the effect of having only one working copy of the NPC1L1 gene.

The gene, called NPC1L1, is of interest because it is the target of the drug ezetimibe, often prescribed to lower cholesterol.

ORLANDO, Fla. — Adding a pharmaceutical form of the B vitamin niacin — but not the drug ezetimibe — to a cholesterol - lowering statin drug appears to reduce artery plaque buildup in patients with coronary artery disease, according to much - anticipated results announced at a press conference November 15.

The results were from a study that was relatively small — only 208 patients — but provided a head - to - head comparison of niacin and ezetimibe, known by the brand name Zetia.

Among medications that lower cholesterol, ezetimibe is not in the widely prescribed class of drugs called statins, which stop the body from manufacturing its own cholesterol.

While ezetimibe is known for its cholesterol - lowering effect, there is debate over whether it also reduces risk of heart disease.

Stein E. Results of phase I / II clinical trials with ezetimibe, a novel selective cholesterol absorption inhibitor.

Ezetimibe: a selective inhibitor of cholesterol absorption.

Statins block cholesterol made in the liver, while ezetimibe blocks the absorption of cholesterol in the gut.