The dog had a long history of severe digestive problems, and the vet brought up the suggestion
of a fecal transplant for the animal.
In part 2 of our conversation with journalist and author Maryn McKenna, she talks about antibiotic resistance in agriculture and human health, MRSA, and offers a brief coda on the subject of fecal transplants
When they are given a microbiome in the form
of a fecal transplant from a human donor, however, they plump up within a day or two because the bacteria help them digest their food and develop a proper metabolism.
Previously, much of the focus on microbiome health benefits has focused on the medical
applications of fecal transplants — taking one person's feces and placing them inside another's colon in the hopes of recalibrating the bacteria in the recipient's gut.
The recently tested pill approach avoids some of the yuck
factor of fecal transplants, but most transplants are done via an enema, colonoscopy or nose tube to the gut.
When it launched, patients in
need of fecal transplants often had to travel significant distances for a visit to one of the few fecal transplant practitioners in the country.
SOMERVILLE, Mass. — OpenBiome, a public stool bank, announced today that it has entered into a collaboration with Finch Therapeutics, a microbiome biopharmaceutical company, to enable FDA
approval of a fecal transplant pill for the treatment of recurrent C. difficile infection.
Smith says regulators have encouraged him to set up a formal study in which hospitals that work with OpenBiome will contribute data on the safety and
effectiveness of fecal transplants.»
When a doctor, relative, or close friend touts the
benefits of a fecal transplant, the message is likely to clash with the voices of our ancestors shouting just the opposite.
THE FIRST KNOWN
RECORD of fecal transplants dates back to 4th - century China, when a doctor named Ge Hong included several mentions in his ambitious collection of therapeutic formulas, Zhou Hou Bei Ji Fang (in English, variously translated as Prescriptions Behind the Elbow for Emergency or Handy Therapy for Emergencies).
Walters points to work from
studies of fecal transplants that have shown there are meaningful differences «in the gut microbiome of lean and obese individuals.»
We are working to produce a defined multi-species probiotic — a synthetic stool treatment that we call «RePOOPulate» — to overcome the
problems of fecal transplants, while still offering a potential cure for CDI.
He is on the
boards of the Fecal Transplant Foundation and the Gastroenterology Association of Naturopathic Physicians, and he is an associate editor for the Natural Medicine Journal.
Understanding your dog's microbiota and the
history of fecal transplants will help you make informed decisions for your best friend regarding the treatment and prevention of gastrointestinal illnesses.
«The excitement about the successful
use of fecal transplants to treat the gastrointestinal infection C. difficile has also led to a premature interest among the general public suffering from ailments for which it is completely unproven and untested.
The team also found that the use
of fecal transplants — which are increasingly used for treating recurrent C. difficile colitis — affected the efficacy of ACT between different strains of lab rodents.