Not exact matches
FlatScope is being developed at Rice University for use as a
fluorescent microscope able to capture three - dimensional data and produce images from anywhere within the field
of view.
Lenses are no longer necessary for some
microscopes, according to Rice University engineers developing FlatScope, a thin
fluorescent microscope whose abilities promise to surpass those
of old - school devices.
This is an E1 protein, on the surface
of a mammalian cell, illuminated with a teal
fluorescent protein and viewed through a laser mounted total internal reflection
microscope.
Using
fluorescent labels, they were able to track the fates
of marked and unmarked chromosomes under the
microscope, from egg cells and sperm to the dividing cells
of embryos after fertilization.
«By the 30th day
of culture, there were obvious clumps
of fluorescent cells visible under the
microscope,» says lead author Valentin Sluch, Ph.D., a former Johns Hopkins biochemistry, cellular and molecular biology student and now a postdoctoral scholar working at Novartis, a pharmaceutical company.
Professor Zhang's team were able to visualize the pinning, stretching and rupturing
of cervical cancer cells by immunostaining different parts
of the cells and viewing them under a confocal
fluorescent microscope and a high - resolution scanning electron
microscope (SEM).
Staining minute samples
of sediment with a
fluorescent dye that binds to DNA, he found he could count cells under his
microscope, just as Boetius would do with her Hydrate Ridge samples many years later.
That required some special equipment: a
microscope that uses lasers and
fluorescent lights to piece together 3D images, a special lighting system to keep the plants healthy during their longer - than - usual time in the spotlight, and a
microscope setup flipped entirely on its side so the plants could grow upright instead
of growing horizontally along a slide.
This is what Ely Silk, 65, a retired business owner and former IBM programmer, did in 2002 when the mercury lightbulb in his regular
fluorescent microscope reached the end
of its one - to two - month life span.
Images taken with a
fluorescent microscope show the activity
of a kinase (green) in tumor cells (bottom) compared to normal cells (top).
When the researchers observed the sterile and dying female worms under a
microscope using a
fluorescent stain to visualize sperm in live worms, they discovered that the foreign sperm had broken through the sphincter
of the worm's uterus and invaded the ovaries.
Researchers used genetically modified mice in which the axons in the corticospinal tract, a bundle
of nerves carrying signals from the brain to the spinal cord, were «stained» with
fluorescent matter visible under a powerful
microscope.
Church's technique employs a
microscope and other off - the - shelf equipment that use bursts
of different
fluorescent colors to distinguish the bases.
The technique, developed by two separate research groups, one at Princeton led by Thomas Gregor, associate professor
of physics and the Lewis - Sigler Institute for Integrative Genomics, and the other led by Nathalie Dostatni at the Curie Institute in Paris, involves placing
fluorescent tags on RNA molecules to make them visible under the
microscope.
Scientists injected
fluorescent molecules into about 150 mouse brain structures and used a high - resolution
microscope to document the molecules as they moved through the brain's «cellular highways,» which need to be in tip - top shape for different parts
of the brain to communicate and coordinate behaviors.
Druckenmiller houses a specialized laser scanning confocal
microscope (the only one
of its kind in the state
of Maine), as well as a scanning electron
microscope and a number
of conventional
fluorescent microscopes, all
of research quality.
For example, with standard
fluorescent microscope filter sets, users can label multiple proteins
of interest with a combination
of green and blue or cyan and yellow moxFPs.
The image was taken using a
fluorescent microscope at the SLIM facility in the School
of Life Sciences.
In a small, dark room, four
microscopes whir and hum while seven monitors glow with
fluorescent images
of biological specimens.
The
microscope and its components, image formation, microscopy in both transmitted and
fluorescent light, Kohler illumination, optical aberrations, objective lens types, phase contrast, interference contrast, polarization, fluorescence microscopy, laser confocal microscopy, two - photon confocal microscopy, super-resolution microscopy, study
of dynamic processes in living cells, immunofluorescence.
Nikon Optiphot - M epi -
fluorescent optical
microscope with a Charged - Coupled Device (CCD) camera mounted directly onto the eye - piece for observing the migration
of colloidal particles within micro models.
I perform direct
microscope screening, analysis
of metaphase plates, Image analysis / Automated Karyotyping (Metasystems), FISH (
Fluorescent in situ Hybridization) on (a) prenatals, (b) haematological disorder,...