Sentences with phrase «of follicle cell»

Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology.

The study revealed that growth factors — especially one known as growth differentiation factor 9 — coming from the eggs drove the feeding tube multiplication and growth process, acting directly upon the genetic machinery of the follicle cells surrounding the egg.

Not exact matches

Same goes for the yak but a bit easier since we could agree upon only say hair still attached to the follicle and extruding from the base cell of a dead yak on ice.

The white blood cells produce an enzyme that destroys the surface of the follicle allowing the bacteria to enter the skin layer causing inflammation of the skin.

This oil can clog those hair follicles, causing a buildup of skin cells and oil.

In 2014, Christiano and other CUMC researchers identified the immune cells responsible for destroying hair follicles in people with alopecia areata and tested an FDA - approved drug that led to complete hair regrowth in a small number of patients.

By encapsulating the follicles in the alginate and providing the growing cells with precise mixtures of nutrients and hormones, researchers at the ONPRC and elsewhere have been able to mimic the ovary's natural structure in the laboratory.

Immune and fat cells in the scalp are obviously also involved in hair loss along with the cells of the hair follicle.

Each is housed within a sac of cells called a follicle.

Nishimura's team proposes that the same process leads to the reduction in stem cells in the follicles of older people, especially as DNA damage accumulates as we age.

Prof. Jean - Christophe Marine (VIB - KU Leuven): «Unexpectedly, this ability to divide and contribute to melanoma development contrasted with the activities of other cell populations, such as melanocyte stem cells found in hair follicles, for instance.

In the ovary of a normal mouse (left), a large follicle is shown at a late stage of development (a light pink oocyte surrounded by follicular cells, inset).

Minuscule, eight - legged Demodex mites nestle head down inside the follicles of the eyelashes, feasting unnoticed on skin cells.

The source of new hair: For the first time, researchers have been able to take human dermal papilla cells (those inside the base of human hair follicles) and use them to create new hairs.

«This method offers the possibility of inducing large numbers of hair follicles or rejuvenating existing hair follicles, starting with cells grown from just a few hundred donor hairs.

«Dermal papilla cells give rise to hair follicles, and the notion of cloning hair follicles using inductive dermal papilla cells has been around for 40 years or so,» said co-study leader Colin Jahoda, PhD, professor of stem cell sciences at Durham University, England, and co-director of North East England Stem Cell Institute, who is one of the early founders of the ficell sciences at Durham University, England, and co-director of North East England Stem Cell Institute, who is one of the early founders of the fiCell Institute, who is one of the early founders of the field.

Before birth, mouse and human ovaries contain an abundant supply of germ cells, some of which will develop into the eggs that will ultimately be released from follicles during ovulation.

In a Nature Medicine paper published online October 29 the researchers report they linked Adjudin to an engineered version of follicle stimulating hormone (FSH), a sex hormone recognized by receptors found only on the Sertoli cells.

But when dermal papilla cells from humans are put into dishes in the lab, they lose their ability to induce the formation of new follicles.

Then came a new step: They carefully extracted the fragile, immature eggs and some surrounding cells from the follicles, and allowed them to further mature on a special membrane in the presence of more growth - supporting proteins.

Their research showed that primordial follicles are highly stable, and that germ - line stem cell activity can not be detected, even in response to the death of half the existing follicles.

Around the time of birth these germ cells have formed a large reserve of primordial follicles — each containing a single immature egg.

What's more, they identified Cas as a critical, tissue - specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

The full readout of what genes are on and off in dermal papilla cells has never been collected before, so researchers now have a new list of thousands of genes to study further that may play key roles in hair follicle development.

That ovarian tissue bears clusters of cells known as primordial follicles, which surround immature precursors to egg cells.

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

Scientists have successfully grown new hair follicles from the skin cells of balding men.

Using one's own cells to generate new follicles is useful because hair color and thickness will match perfectly with the rest of someone's head of hair, Christiano notes.

Six weeks later, spheroids from five of the seven donors had coaxed the skin cells around them to start rearranging, forming the telltale shape of a hair follicle, the team reports online today in the Proceedings of the National Academy of Sciences.

«Earlier menopause has been reported in women undergoing radioactive iodine treatment, and given the finite number of primordial follicles women start with at birth, radiation injury to germinal cells is not expected to be reversible,» she cautioned.

These microscopic, eight - legged mites live in the follicles of our eyelashes, eyebrows, and nose hairs, where they feed on dead skin cells and oil.

«By analyzing mice with the WNT10A mutation, as well as tissues from human patients with WNT10A mutations, we found that WNT10A regulates the proliferation, but not the maintenance, of stem cells in hair follicles,» said Sarah Millar, PhD, vice chair for Basic Research in the Department of Dermatology.

First, imaging experiments revealed that Tregs have a close relationship with the stem cells that reside within hair follicles and allow them to regenerate: the number of active Tregs clustering around follicle stem cells typically swells by three-fold as follicles enter the growth phase of their regular cycle of rest and regeneration.

Moreover, the stressed mice's gray hairs and the cell populations in their follicles were indistinguishable from those of elderly mice, suggesting that genotoxic stress might drive natural graying as well.

In this new study, when researchers isolated the follicles, they substantially reduced the presence of cancer cells.

Ligna Li and Robert Hoffman of AntiCancer, a biotechnology company in San Diego, have perfected a technique for delivering DNA into hair follicle cells.

The researchers isolated primary ovarian follicles, consisting of the oocyte and surrounding cells.

Dr Yu's PhD student Mr Yew Ann Leong, who conducted a large portion of the research, also from the Monash Biomedicine Discovery Institute, said that although some infections including HIV could hide within B cell follicles, these killer T cells are specialised to eradicate this hidden virus pool.

The team studied skin cells, called dermal fibroblasts, that help hair follicles develop, wounds heal, and generally maintain the structural integrity of skin.

But hair growth depends on the ability of cells in the hair follicles to keep dividing and so producing cells which die and are built into the hair shaft.

Concurrently, this dermal cell aggregation triggers the mechanosensitive activation of β - catenin in adjacent epidermal cells, initiating the follicle gene expression program.

Within every hair follicle is a population of melanocyte stem cells.

ICOS gets antibody production started by promoting the maturation of Tfh cells, which migrate into compartments or follicles of immune organs such as spleens and lymph nodes, which themselves are full of B cells.

What they did not know in detail is what happens after those stem cells move down to the base, or bulb, of hair follicles and which cells in the hair follicles produce SCF — or that cells involved in hair shaft creation make the KROX20 protein, he said.

Once in contact with Tfh, some B cells become activated, migrate to an area of the follicle called the germinal center and start dividing rapidly under influence from Tfh.

Scientists already knew that stem cells contained in a bulge area of hair follicles are involved in making hair and that SCF is important for pigmented cells, said Dr. Le, a member of the Hamon Center for Regenerative Science and Medicine.

That geometry directly links to whether or not the ovarian follicles, organized hormone - producing support cells surrounding an immature egg cell, will survive in the ovary, which was one of the bigger findings in the study.

Follicles, or small clusters of cells, come out of the scalp when hair is plucked.

In the study, Stephen Maricich and colleagues identified a subpopulation of Atoh1 - expressing cells in hair and whisker follicles within mouse skin that exclusively give rise to Merkel cells during development and adulthood.