The synchronized nature
of gametogenesis allowed us to investigate phosphorylation signaling during its first minute in Plasmodium berghei via a high - resolution time course of the phosphoproteome.
Unlike meiosis, which is required in both males and females, most other components
of gametogenesis are sex - specific or sex - biased, such as sperm tail formation.
This is consistent with a model in which the pre-existing somatic cell machinery underwent reproductive specialization during the evolution
of gametogenesis in multi-cellular ancestors.
In their latest study, they generated three different medaka mutants to demonstrate that the feminizing effect of germ cells is not a result of the progression
of gametogenesis or a sexual fate decision of germ cells.
«However, the molecular basis of, and the stage
of gametogenesis critical for, feminization remain unknown.»
Ana Riesgo states that «they have more complex morphological characteristics than other sponges and, in the case of Corticium, they follow the same process
of gametogenesis than cnidarians.»
Not exact matches
The findings suggest that the information on the X and Y chromosomes that makes this division possible is primed during
gametogenesis — the process
of creating ovum or sperm cells — in the parents.
They included cloning (somatic cell nuclear transfer, accomplished in many placental mammals), stem cell
gametogenesis (has been done in mice), direct engineering
of early stage embryos (has been done in several mammals), embryonic stem cell editing, and primordial germ cell (PGC) editing.
The lack
of a universal male reproductive factor among all animal lineages, while consistent with rapid evolution
of male reproductive genes, is in contrast to the prevalence
of sexual reproduction and in particular to the similarity in male
gametogenesis among metazoan animals [34], [69].
Interestingly, this result shows that Boule has a spermatogenesis - specific requirement conserved in at least two distant lineages
of bilateral animals, making it a strong candidate for a conserved male
gametogenesis factor between Drosophila and mammals.
Despite a large number
of sex - specific
gametogenesis proteins uncovered in the model organisms Drosophila, C. elegans and mice, no conserved male - or female - specific gametogenic factors common to all lineages
of animals have been clearly demonstrated [30]--[33].
The fundamental component
of animal sexual reproduction is
gametogenesis, the differentiation
of sexually dimorphic male sperm and female eggs.
Few genes have exhibited a sex - biased, reproductive - specific requirement beyond a given phylum, raising the question
of whether any sex - specific
gametogenesis factors could be conserved and whether
gametogenesis might have evolved multiple times.
Given that mouse Boule is required for sperm production like fly boule but different from C. elegans daz - 1, we propose that Urbilaterian Boule had an ancestral function in male
gametogenesis which was lost during the evolution
of the nematode lineage (Figure 7).
These phenotypes differ from the sex - biased infertility
of Boule mutations in all species examined, and the
gametogenesis defects in Boule mutants are much less variable than those from either Vasa or Piwi mutants across species [21]--[23], [61], [78], [79].
The current findings could provide important clues to determine the culture conditions for promoting the differentiation
of primate ES cells into mature gametes, and to understand molecular mechanisms
of primate
gametogenesis including the timing
of germ cell induction, the regulation
of germ cell gene expression, and the response to growth factors for germ cell differentiation.
If both developmental processes evolved from an ancient primitive spermatogenesis prototype, one would predict the presence
of at least some common male
gametogenesis - specific regulators in both lineages.
Characterization
of a TUTase / RNase complex required for Drosophila
gametogenesis.
However, the major steps
of dimorphic
gametogenesis among animals are very similar.
Since the nematode Boule homolog is only required for ovarian function but not male
gametogenesis, and Boule transcripts have been detected in the ovaries as well as in the testes
of some other species [53], [57], [59], we wondered if such ovarian expression in sporadic species is a lineage - specific phenomenon or if it is a common feature.