Sentences with phrase «of gene action»

Not exact matches

They are seeking damages from former CEO Gene Isenberg and current CEO Anthony Petrello as well as members of the board of directors in a federal class action lawsuit filed by the Erie County Employees Retirement System.

On August 5, 2003, the House of Bishops of the Episcopal Church USA (ECUSA), following initial action by the House of Deputies of ECUSA's General Convention, gave its consent (by a ratio of roughly 60 - 40) to the election of the Reverend V. Gene Robinson to become the next Bishop of the....

Speaking about the film recently in Los Angeles, Cera — who in this film, takes some refreshingly bold steps away from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun of the Dead and Hot Fuzz) discussed the meaning of the film, the stretching Cera had to go through for the role, and the way in which the film's hyperkinetic action sequences are really just the same as the dance scenes in Grease or a Gene Kelly movie.

This is nature in action and a small part of the inevitable process that will remove religiousness from the gene pool.

There is no use cheating yourself — if you are not one of these lucky women who seem to have the return to their pre-pregnancy shape encoded in their blood or genes, then it will require time, effort, systematic actions and appropriate diet.

The finance chairman and a finance committee member of Gene Locke's mayoral campaign helped bankroll the conservative political action committee that sent out an anti-gay mailer targeting City Controller Annise Parker and other municipal candidates earlier this month, according to Texas Ethics Commission documents.

Sheriff Gene Conway spoke about the heroic actions of David Goetzmann, 28, of Skaneateles and Eric Marcinkowski, 40, of Syracuse, before presenting both of them with the Onondaga County Sheriff's Civilian Recognition Award at the Skaneateles Firehouse.

LCV Action Fund President Gene Karpinski praised Bishop's support of clean energy legislation, saying he «stands with the people of New York who need clean energy jobs now, and not with the Big Oil companies and special interests who are blocking progress in Washington.»

The research team also found that the action of a gene, ATG16L1, kept TNF alpha - driven inflammation from triggering the self - destruction of too many Paneth cells, by an explosive process called necroptosis.

This action can result in the activation of genes that had been switched off, and could be the cause of the recovery of synaptic strength.

More to the point, your health, your life span — and even some of your actions — may have more to do with the genetic variation in those microorganisms you host than they do with your own genes.

Simon Mead of University College London says the «anti-kuru» gene is the most clear - cut evidence yet of human evolution in action.

The discovery of the master gene that sends them into action promises a host of new treatments for infections, cancer and other diseases.

Over the past 15 years, the GFP gene has enabled scientists to watch a plethora of previously murky biological processes in action: how nerve cells develop in the brain, how insulin - producing beta cells form in the pancreas of an embryo, how proteins are transported within cells, and how cancer cells metastasize through the body.

The policy — in the form of first Office Actions on a series of applications for patents on expressed sequence tags, ESTs — could greatly complicate basic gene therapy research by substantially allowing patents for small sequences of a gene that may later be used by the patent holder to corner ownership and uses of entire genes.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

The studies were the first to show that the action of genes could be modulated by structures called methyl groups, a subject about which Szyf knew precisely nothing.

The main aim was to identify the genes in the progenitor that allow it to resist the action of the insect's immune system.

The film is a tantalizing first glimpse of how researchers might someday study enzymes in action or watch how mutations cause genes to go awry.

The researchers discovered the actions of multiple independent meiotic drivers in fission yeasts in an earlier study, reported in 2014 in eLife, but didn't know which genes were responsible, or how they destroyed gametes that didn't inherit the genes.

But the mutant form of the ADAM10 gene did exactly the opposite: It blunted the action of the enzyme, resulting in the production of more of the toxic proteins.

First described in the 1990s — a discovery that led to the 2006 Nobel Prize — RNAi is a process by which organisms suppress the expression of target genes through the action of small RNA segments that bind to corresponding gene sequences.

Zeroing in on NANOG, the scientists found that low oxygen conditions increased NANOG's mRNA levels through the action of HIF proteins, which turned on the gene for ALKBH5, which decreased the methylation and subsequent destruction of NANOG's mRNA.

According to some researchers, that essentially proves that intelligence relies on the action of a multitude of genes after all.

Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

In 2002 Joslin researcher Steven Shoelson knew that salicylates block the action of a protein called NFkB, a genetic master switch in the liver that helps launch a cascade of genes that cause the chronic, low - grade inflammation associated with diabetes.

«Scientists determine structure of enzyme linked with key cell - signaling protein: Findings aid understanding of how modifications to cell - signaling protein affect its action in turning genes on and off.»

HDACs, including HDAC3, remove these acetate groups, an action correlated with reduced expression of genes.

The role of these genes is to control the actions of other genes.

Clicking through 5000 hypertext links on the site's 1500 pages, visitors can trace the complex web of gene expression and protein action that transforms the fruit fly from a one - celled embryo into a six - legged adult, exactly as the saga unfolds in real - life flies.

If we are nothing but a bag of genes and chemicals, as Steven Pinker, Francis Crick, and others have famously written, do we bear responsibility for our own actions?

«We anticipate a similar mode of action may operate in other organisms because similar RNAs have been found for clock genes in mice.

Are actions and behaviors a result of genes or environment?

Furthermore, when they blocked the action of the gene using RNA interference, the cell proliferation index was reduced.

The gene therapy was also designed to inhibit action of the myostatin gene, which stops muscle cells from growing.

The gene produces a protein that is embedded in the membrane of cells, and is known to bind anthrax toxins internalizing them into the cell where they exert their action.

The aim now is to identify the molecules that regulate expression of this gene upstream, and those that interact with the enzyme, to understand their modes of action and determine how normal MOCOS expression could be restored..

«The goal with the dependency map is to identify genes of consequence and reverse engineer what their action is, to devise better therapies.»

Toxicologist Craig Harris of the University of Michigan, Ann Arbor, who has studied thalidomide's effects on gene expression, says that the new data are consistent with some theories of the drug's action, however.

Kuruvilla's lab group — which has been studying the peripheral nervous system for years — found that abundance of a particular gene product in Down syndrome puts a brake on NGF's actions in fostering nerve development.

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown for the first time that ensembles of genes within the striatum — a part of the brain that coordinates many primary aspects of our behavior, such as motor and action planning, motivation and reward perception — could be deeply involved in the disorder.

If genes are at the mercy of behavior, but behavior is also at the mercy of genes, then our actions can be determined by forces that originate within us as well as by outside influences.

As an example, Martin von Lohuizen of the Netherlands Cancer Institute, says Berns's own laboratory has developed a mouse with a gene called PIM1 which rarely causes tumours but sensitises the mouse to the action of a second carcinogen.

«Our findings were quite surprising because females typically just select sperm from males of their own species during fertilization, an action that does not lead to long - term consequences because there is no gene flow between the species,» said Asher Cutter, associate professor of ecology and evolutionary biology at the University of Toronto.

Neuroscience gets invoked these days to explain virtually any behavior — from the actions of Wall Street traders to a «God gene» that makes us devout.

Dr Fanni Gergely from the University of Cambridge said: «The development of a healthy human brain is an incredibly complex process that relies on stem cells and the coordinated actions of many genes.

And on page 1693, another team reports further evidence of the action of natural selection in people: A gene expressed in microglia, immune cells of the nervous system, produces a protein found only in humans.

Based on analyses of over 600 drug and breast cancer cell pairings, researchers showed that, for some cells, drug exposure can cause significant changes in gene expression — indicating the successful action of a drug on its target — without affecting cell growth or survival.

The study, published in Cell Reports, discovered that the action of a gene called FOXO is inhibited in flies given a high sugar diet in early life, causing long - term effects.

Kinases are enzymes that control the actions of genes, and kinase dysregulation has been implicated in many cancer types.