Sentences with phrase «of gene regulatory networks»

Synthetic biology is a promising new tool to study the function and properties of gene regulatory networks (GRNs) by building them from first principles.

Widespread contribution of transposable elements to the innovation of gene regulatory networks.

In fact, our present understanding of morphogenesis indicates that new phyla were not made by new genes but largely emerged through the rewiring of the gene regulatory networks (GRNs) of already existing genes (1).

We focus on developing computational methods and tools for (a) analyzing large - scale gene expression data related to human cancer in search for gene markers and disease sub-categories, (b) identifying regulatory elements such as miRNA precursors and their targets in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks.

We studied design principle of gene regulatory networks subject to intrinsic noise and extrinsic perturbations.

Together with long - standing collaborators Edward R. Dougherty (Texas A&M University) and Wei Zhang (M.D. Anderson Cancer Center), he co-developed the model class of probabilistic Boolean networks (PBNs), which was applied to the study of gene regulatory networks in cancer.