Sentences with phrase «of gene sets»

The ES was computed for every gene set using actual data and the maximum ES (MES) over all of the gene sets was recorded.

Still, he notes that the predictive power of the gene set is low, and «because of the experimental design we can't really say that other exposures might [not] be an issue.»

Not exact matches

At last year's Brainstorm Health conference in San Diego, Bergh found himself sitting at dinner with Othman Laraki, the cofounder and CEO of Color Genomics — a company that extracts the DNA from a customer's submitted saliva sample and then looks for a set number of gene mutations known to be associated with increased risk for developing certain hereditary cancers or heart conditions (depending on the test).

Instead of just focusing on human DNA, which in the other studies had yielded limited results, she looked at multiple sets of genes — and not just from humans.

Cancer - focused CRISPR technology involves taking a set of molecular shears and the guiding molecule Cas9 in order to cut out unwanted genes in immune cells that may help proliferate cancers.

Mitochondria — our cells batteries — contain a set of genes separate from the DNA bunched up inside our nucleus.

Now that the barrier of editing genes in the hospital setting has been broken, these companies and more have pipelines of gene - editing innovation coming to a hospital near you in the next few years, as clinical trials are approved and new ways to cure formerly incurable diseases go mainstream in our lifetimes.

To coax the apples to create these particular anti-browning RNA molecules, the scientists gave the apple extra copies of the browning gene that were tweaked to set off the plant's interference mechanism.

Ever hear of mendle, or genetic engineering or really anything have to do with genes and dna and how dna from two individuals helps create a third with genetic traits inherited from both sets of dna either as dominant or recessive.

To avoid allowing the selfish genes to set the moral agenda, Dawkins states a basic proposition that he apparently regards as self - evident — essentially the Golden Rule — and then hastily drops the subject because to develop that line of thought further would undermine his whole project.

The death penalty should be abolished not for religious reasons (also religious people seem to approve of the dath penalty — which to me makes no sense) but because every person who is killed is one less set of DNA to be passed on to succeeding generations, and who knows what those wasted genes could mean for the future of the species?

I suspect you are not carrying a set of good genes with reference to intelligence so you can not breed.

This would require a fuller set of genes than people of today have.

Richard Dawkins, in his celebrated book, The Selfish Gene, exemplifies the same position.3 And a similar reduction of biology to a molecular science may be found in the writings of E.O. Wilson, Ernst Mayr, Jacques Monod and numerous other highly respected scientific writers.4 In Chance and Necessity, for example, Monod gives one of the most forceful renditions of the view that biochemical analysis is «obviously» the sole avenue to understanding the secret of life.5 Decades ago Jacques Loeb had already set forth the program of inquiry still emulated today by many biologists:

Simply put, a phenotype is an observable set of properties that varies among individuals and is directly dependent on that individual's genes.

However, if I was an ancient Israelite, and I saw things like the Red Sea parting, staff turned into snakes, and the Shekinah glory, and prophets predicting specific future events with 100 % accuracy, and other nations setting their face against Israel to destroy her and / or engaged in human sacrifice, and they weren't typical humans but were actually a group of hybrids like the Nephalim or the Rephaim that were polluting the gene pool to try to foil God's plan of ultimately bringing a Messiah to save all mankind one day, and God wanted them to repent and sent them warning after warning, and they refused, and God commanded me thus....

Because of virgin birth, the genes were not passed down to him, but a special set of white genes was passed down to make Jesus.

But it is not actually the crucial question, which is, What controls the activity of the complex interacting set of genes, which produces a nerve cell or a muscle cell?

This dataset contains millions of genomic sequences from a diverse set of rice varieties that, when combined with phenotyping observations, gene expression, and other information, provides an important step in establishing gene - trait associations, building predictive models, and applying these models to breeding.

Division 1 of this Standard sets out the permission and conditions for the sale and use of foods produced using gene technology.

This means that the genes you will find in both sets of chromosomes are the same.

A gene is a set of instructions held on a string of DNA telling a cell how to make a specific protein or enzyme molecule.

Each of us with breast cancer (and I include men) has a different set of genes, personal backgrounds and lifestyles.

Our conference for 2018 is packed full of fascinating topics such as the antibacterial properties of human milk carbohydrates, breastmilk as a communication and gene expression tool, management of chronic breast pain, the physiology of the milk ejection reflex, collaboration in high conflict settings, and so much more!

They are no more alike than any sibling set, sharing about 50 % of their genetic markers in a unique combination of genes from both parents.

To generate a rich source of potential vaccine and drug target candidates, the team identified a set of genes that are more active in certain stages of the parasite life cycle and within the parasite's gut.

No particular genetic variant was shared across all synesthetes in all three families, suggesting there is no single «synesthesia gene» or set of genes.

Two newly discovered members of the mimivirus family, both called tupanviruses and both with tails, have the most complete set of genes related to assembling proteins yet seen in viruses (SN Online: 2/27/18).

By using this tool to analyze their data the scientists were able to catalogue active alleles in a comprehensive set of mouse tissues, or the mouse «Allelome,» and gain an insight into how this differential gene activity is regulated.

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

Ten sets of bacterial genes have similar, newly discovered defense roles, researchers report online January 25 in Science.

«The advantage of being able to adjust a set of genes identified as key autism risk factors may explain the strong and long - lasting efficacy of this therapeutic agent for autism.»

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

The study, published online today in Science Translational Medicine, further points to a master switch for these gene sets as a potential target of future therapies.

New research at the University at Buffalo reveals the first evidence that it may be possible to use a single compound to alleviate the behavioral symptoms by targeting sets of genes involved in the disease.

PER and TIM block the ability of CLOCK to turn on these genes at the same time as they are producing the oscillations of the central feedback loop — setting up extended patterns of cycling gene activity.

However, the MIT team adapted it to randomly turn on or off distinct gene sets across large populations of cells, allowing the researchers to identify genes that protect cells from a protein associated with Parkinson's disease.

Whether or not a gay gene, a set of gay genes, or some other biological mechanism is ever found, one thing is clear: The environment a child grows up in has nothing to do with what makes most gay men gay.

A transcriptome is the set of all RNA molecules transcribed in each cell type, and a readout on which genes are turned in that cell at the time.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

Biologists now know that the genome sequence holds only a small part of the answer, and that key elements of development and disease are controlled by the epigenome — a set of chemical modifications, not encoded in DNA, that orchestrate how and when genes are expressed.

The disorder arises when some or all of an extra copy of chromosome 21 is present, but exactly how this additional set of genes disrupts development, leading to learning difficulties and other symptoms of Down's, isn't clear.

Identical twins — who share the same genes — reported similar experiences, while fraternal twins, with some different sets of genes, often differed in their responses.

To put the kibosh on the idea that the evolution of a gay gene presents an unsolvable conundrum, Sergey Gavrilets, a theoretical evolutionary biologist at the University of Tennessee, developed a mathematical model of how a set of what he calls «sexually antagonistic» genes might evolve.

To handle the staggering task of testing all of the potential combinations of genes, Venter and his colleagues are going to set up an army of robots to build a million synthetic organisms a day.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

Extracting clinically relevant information pertinent to a complex disease process, drawing from a data set of 19,000 genes, required a creative rather than systematic research approach.

«The state of the art right now is targeting two or three genes simultaneously and then looking at the effects, but we think that perhaps the gene sets that need to be modulated to address some of these diseases are actually broader than that,» says Lu, who is the senior author of the study.

The finding suggests that other AAVs used for a gene therapy targeting the brain or spinal cord might be improved by having the same or a similar set of amino acids.