Sentences with phrase «of genes coding»

Epigenetic modifications of promoter regions that influence the transcription of genes coding for crucial protein products can be induced by the environment.

Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

Previous work in Atlantic salmon has shown that the diversity of genes coding for the MHC binding site is lower in animals that typically live in lower temperature conditions.

She has tracked dramatic increases in the prevalence of several genes and suites of genes coding for drug resistance.

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

Another connects post-traumatic stress disorder to methylation of the gene coding for neurotrophic factor, a protein that regulates the growth of neurons in the brain.

Sickle cell disease is a recessive genetic disorder caused by a single mutation in both copies of a gene coding for beta - globin, a protein that forms part of the oxygen - carrying molecule hemoglobin.

Researchers found that kochia has evolved to have multiple copies of a gene code that targets glyphosate.

Ten of those genes code for odor receptors, which researchers anticipate could become targets for future louse repellents.

All of these genes code for transcription factors, which are proteins that control the expression of other genes.

One of these genes codes for a protein that the team dubbed claudin - like apicomplexan microneme protein (CLAMP), which has a strong effect on the parasite's invasion of host cells.

To the group's surprise, two of those genes code for proteins that restrict a jumping gene called long interspersed element - 1or L1, for short.

Unusually, many of its genes code for proteins that help shuttle materials into or out of the cell, which marks the bacterium as a generalist equipped to deal with a broad range of soil conditions and food sources.

One of the genes codes for a protein that allows neurons to respond to serotonin, a neurotransmitter involved in mood.

• Combining stem cells with gene therapy, an international collaboration announced the success of a pilot study to treat X-linked adrenoleukodystrophy (ALD), a fatal brain disease caused by a mutation of the gene coding for the ALD protein.

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

Traversari C, van der Bruggen P, Van den Eynde B, Hainaut P, Lemoine C, Ohta N, Old L J, Boon T. Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes.

Whole - exome capture of gene coding regions and a small shoulder region of intron — exon boundaries was performed using SeqCap EZ Exome V3 (64.1 Mb; Nimblegen).

They also described the gene's size and genetic deletions associated with disease, including a very large deletion of the gene coding for dystrophin found in a patient with mild disease.

Approximately 20 % of fALS are due to mutations of the gene coding for the enzyme copper — zinc superoxide - dysmutase (SOD1)(2).

Like the bacteria that cause gonorrhea, members of T. pallidum have multiple copies of the gene coding for the proteins that allow them to adhere to human cells — perhaps, as in the case of gonorrhea, these genes allow T. pallidum to alter their surface proteins in order to escape recognition by the immune system.

Not exact matches

That's not to say gene editing is new (it isn't), but Crispr simplifies the process by using molecular scissors that can be precisely targeted to snip out aberrant regions of genetic code, which can then be replaced with the correct sequences.

Feeling that you're part of a community is also apparently a hefty immune system boost, Seppälä says, citing research that «shows that genes impacted by social connection also code for immune function and inflammation.»

Molecular biology's famous «Central Dogma» states that DNA, the living computer code that makes up our genes, is first transcribed into RNA, which is then translated into specific proteins, which ultimately do the 24/7 work of the body and form its many structures.

That's because, in theory, thanks to that single wisp of intermediate code, the genes implicated in many diseases should be easier to quiet.

Because gene drives can pass such changes down from one generation to the next, each potential alteration in the code of life could have a lasting and unknowable effect.

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

And in any case «the gene» is a purely analytic sub unit of the greater and more significant complex that is the genetic code along the chromosomes of any organism.

From a creationist point of view, the gene is very litterally the computer code of life written by the creator.

At the heart of your Behe article are two concessions which simply don't support ID: 1) the ability of evolution to produce functional novelty via gene duplication / mutation and exaptation exists; and 2) that evidence of «new information» in the form of «new Functional Coded elemenTs, or «FCTs»» also exists.

The researches found that the transgene was inserted into an active region of the genome, thereby disrupting the coding sequence and ultimately the function of the plants own OsAux1 gene.

Epigeneticists have found that our cells carry a type of memory of the experiences of our ancestors — not only that, but 95 % of our genes aren't yet coded at birth, dependent on nurturing and the environment to determine their fate.

(Some research has homed in on a gene that codes for a transporter of the brain chemical serotonin.)

This type of RNA was different, though, in that it didn't make up or code for the instructions of a protein like a traditional gene but instead was «noncoding.»

It's up to the scientific community to maintain and enforce international codes of ethics regarding clinical research on gene therapy techniques, the authors say.

All animal cells are made up of two genomes, the nuclear genome with 10,000 s of protein coding genes and the mitochondrial genome with 13 protein - encoding genes.

The scientists used CRISPR, a gene - editing tool, to alter inserted genes so that the enzymes for which they coded would work most efficiently amid the exotic acidity, osmotic character and chemical composition of their new home.

While DNA and its 20,000 protein - coding genes can be thought of as static «hardware,» the epigenome is the «software» that coordinates its operation.

The gene for fur coloration resides on the X chromosome, while each of the two X chromosomes codes for a different color: black or orange.

This finding came as a surprise since it was assumed that as a consequence of the evolutionary divergence between human and other animal viruses, the genes that code for LANA could not be switched.

About one in 8,000 children is born with some form of SMA in which mutations in both copies of the gene that code for the survival motor neuron (SMN) protein cripples its production.

The disease results from a single mutation in the gene that codes for one of the protein chains that make up the hemoglobin molecule.

Alpha -1-antitrypsin deficiency (A1ATD) is the most common genetic disease of the liver, and is caused by a single nucleotide change in the gene that codes for alpha -1-antitrypsin (A1AT), an enzyme inhibitor that normally protects bodily tissues.

To generate the models, Jackson created two mutated versions of the PrP - coding gene by changing a single codon — one of the three - nucleotide «words» in genes that code for the various amino acids in proteins.

The human genome contains some 20,000 - 25,000 protein - coding genes, which is surprisingly similar to the number of genes in worms and flies.

One of the genes most often associated with anorexia nervosa codes for BDNF, a factor involved in neuron survival and neuroplasticity.

By directly manipulating a portion of the prion protein - coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans.

Gene discovery was greatly facilitated by a new exome sequencing technology, which analyzes all protein - coding regions of the genome at once.