Sentences with phrase «of genes encoding those proteins»

No. 5,817,479, entitled Human Kinase Homologs, claims 44 ESTs which are fragments of genes encoding protein kinases.

She and her colleagues found that expression of a variety of genes encoding proteins related to collagen and extracellular matrix, was reduced.

Since the successful sequencing of the human genome, interest in the group of genes encoding proteins responsible for DNA remodeling has grown exponentially.

It has been suggested that a high serum cholesterol level is a risk factor for (AD), and that some polymorphisms of genes encoding proteins regulating cholesterol metabolism are associated with AD development.

Not exact matches

As the video explains, these traits are due to the tiny molecular machines in our cells known as proteins, which are encoded by bits of DNA called genes.

All animal cells are made up of two genomes, the nuclear genome with 10,000 s of protein coding genes and the mitochondrial genome with 13 protein - encoding genes.

In theory, blocking the production of proteins encoded by these genes could delay or prevent people becoming ill.

This search identified a previously undiscovered gene cluster encoding a new botulinum neurotoxin and accessory proteins in the genome of a species of Enterococcus bacteria isolated from cow faeces.

The artist of this depiction, Raquel Lieberman, is the principal investigator of the team that confirmed a Y - shaped structure, the first ever found that was encoded as such by a gene and not constructed out of protein component parts.

Genes encoding ribosomal proteins, DNA replication and repair machinery, oxidative stress, and purine biosynthesis were differentially expressed in Wolbachia during the development of B. malayi female worms, suggesting a role of the bacteria in worm reproduction.

One of the crucial adaptations involved changes in a gene that encodes a viral protein used to enter cells.

The gene aquaporin - 1 encodes channel - forming integral protein (CHIP), a member of a large family of water transporters found throughout nature.

The study results build on genetic and epigenetic basics, including that the blueprint for the human body is encoded in genes that direct the building of one or more proteins.

Other teams are trying to introduce the proteins encoded by the genes directly into cells, while Yamanaka is experimenting with «microRNAs» — snippets of RNA that help regulate gene activity.

Some of these genes are involved in making the proteins encoded by the viral DNA and may make it easier for Mimivirus to co-opt host cell replication systems.

The last gene of interest was TGM5, which encodes a protein that stabilizes protein groups.

These represent about 50 percent of the total estimated number of human protein - encoding genes.

In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called olfactory receptors.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

Goats as Drug Factories Initially, GTC generated transgenic goats by microinjecting into the developing nucleus of a one - cell embryo a gene encoding the desired human protein (along with DNA that promotes activation of that gene in milk).

Genes that encode therapeutically useful proteins can be of enormous scientific and financial value because they permit large - scale production of the encoded proteins through recombinant DNA technology.

Its genome consists of just nine genes encoding 15 different proteins.

They had been working with a worm model of Duchenne muscular dystrophy, a severe form of the disease that strikes young boys and is caused by mutations in the gene that encodes the dystrophin protein.

The pilot project tested a dozen or so of the most commonly used gene promoters (regions of DNA that facilitate gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that control protein translation) to determine whether they behave consistently in different cellular contexts.

This gene is one of many known to be involved in the formation of emotional memories, and encodes an enzyme called protein kinase C -.

The major mechanism of resistance involves the introduction of mutations in genes encoding penicillin - binding proteins.

«This gene encodes a protein which recognises the presence of a certain number of cold - inducing microbes in a cell, such as the respiratory syncytial virus (RSV) or rhinoviruses,» explains Samira Asgari of EPFL, who designed the experiments.

A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins.

What emerged from their work was the finding that the girl had inherited two differently mutated copies of the gene IRF7, which encodes a protein that amplifies the production of interferon, a critical part of the body's response to viral infections.

SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.

PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.

Researchers would then have to pore through four or five databases for each one, trying to discern which genes (or the proteins they encode) have features most likely to affect the biology of the disorder — a painstaking task.

The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

Mutation around the region of the human SOX9 gene, which encodes the Sox9 protein, causes campomelic dysplasia, a congenital disease that is accompanied by skeletal abnormalities and other conditions.

Closer scrutiny revealed that one gene, encoding a protein called TIGR, was mutated in five of the eight families tested, but not in 100 healthy controls.

The researchers found that the blond hair commonly seen in Northern Europeans is caused by a single change in the DNA that regulates the expression of a gene that encodes a protein called KITLG, also known as stem cell factor.

In the new work, Miranda M. Lim of Emory University and her colleagues inserted a gene that encodes for the vasopressin receptor protein directly into the brains of male meadow voles.

Carmona - Mora concentrated on the space between genes — part of the genome once considered «junk DNA» because it doesn't encode proteins.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

But BRCA is just one of the many genes that encode important proteins in the DNA repair pathway known as homologous recombination,» says the study's lead author, Arielle Heeke, MD, a clinical fellow at Georgetown Lombardi Comprehensive Cancer Center.

Functional analyses indicate that MFSD12 encodes a lysosomal protein that affects melanogenesis in zebrafish and mice, and that mutations in melanocyte - specific regulatory regions near DDB1 / TMEM138 correlate with expression of ultraviolet response genes under selection in Eurasians.

«We have developed a bioinformatics approach that suggests that such changes might alternatively occur through changes in the interactions of proteins encoded by the gene.»

June's team also wants to knock out two gene segments that encode different portions of the protein that makes up a T cell's primary receptor so that the engineered NS - ESO - 1 receptor will be more effective.

During this time, transcription — the conversion of gene «recipes» encoded in DNA to mRNA, the messenger that carries the recipe to the cell's protein - making machinery — is completely shut off.

Our genes can be thought of as packets of information written in sequences of DNA bases, which encode proteins that perform the functions necessary for life.

Genes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protGenes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protgenes that doesn't encode proteins, tells them when to make their proteins.

Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters).

Women prefer the smell of T - shirts worn by men whose major histocompatability complex genes — which encode the proteins that make up an important part of our immune system — are different from their own, and vice versa.

«We introduce a gene that encodes a light - sensitive protein, and we target the expression of that gene to a subset of retinal cells.»

The MHC is a family of genes found in all vertebrates that encodes vital proteins in the immune defense system.