A well - known factor in the decline of stem cell function is the
loss of genome integrity, for example, caused by the appearance of somatic mutations.
She received a position as Chargée de Recherche CNRS in 2001 in the Département Intégrité du Génome (UMR7175 - ESBS, Illkirch, France) directed by Gilbert de Murcia to study the function of PARP - 2 in the maintenance
of genome integrity.
Julia's lab studies chromosome organization and the maintenance
of genome integrity, with mechanisms of telomere function as a springboard.