Sentences with phrase «of genome sequences»

Comparative analysis of genome sequences from four strains of the Buchnera aphidicola Mp endosymbion of the green peach aphid, Myzus persicae

The lab creates widely used software and databases, performs applied analyses of genome sequences, and partners with diverse research teams on projects at the intersection of the computational and life sciences.

The Wasserman laboratory focuses on the creation, evaluation and application of computational methods for the analysis of genome sequences, with international strength in the study of cis - regulatory elements regulating gene expression.

High throughput sequencing has accelerated the determination of genome sequences for thousands of human infectious disease pathogens and dozens of their vectors.

The transcriptome, Katze said, will enable researchers to improve the annotation of the genome sequences of some of these species.

As a result of the large amount of genome sequences now available for different Plasmodium species, a complex pattern now emerges in the MSP7 / 7 - like tree, suggesting that the different MSP7 proteins likely have different functions.

A key program of VIOLIN is Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.

As a part of VIOLIN, we have developed Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.

With the availability of genome sequences from representative species in whole phyla, rigorous quantitative measurements of genetic distance based on DNA sequence divergence has been used to test existing evolutionary trees and to re-classify organisms in all kingdoms.

Bioinformaticians identified this protein and its potential connection to CRISPR by scanning the public database of genome sequences.

«Our work demonstrates that the generation of genome sequences from a large number of archaic human individuals is now technically feasible, and opens the possibility to study Neandertal populations across their temporal and geographical range,» says Janet Kelso, the senior author of the new study.

Overall, a study of the genome sequences of 57 colorectal cancers showed, on average, 4.42-fold more somatic nuclear mitochondrial DNA as compared to matched healthy blood controls.

In December the US Federal Committee on Foreign Investment cleared the acquisition of Complete Genomics, a Californian DNA sequencing company, by BGI - Shenzhen, a Chinese operator of genome sequencing centers.

For Chad Nusbaum, co-director of the Genome Sequencing and Analysis program at the Broad Institute of Harvard University and the Massachusetts Institute of Technology (MIT) in Cambridge, the event was a professional milestone.

And since the cost of genome sequencing has plummeted to one - thousandth of its initial cost, it's clear that the Neanderthal, a 700,000 - year - old horse and the woolly mammoth will simply be the first of many ancient genomes to be sequenced.

Now Pääbo and his colleagues have devised a new method of genetic analysis that allowed them to reconstruct the entire Denisovan genome with nearly all of the genome sequenced approximately 30 times over akin to what we can do for modern humans.

Many of the Neandertal specimens, for example, have only a small fraction of their genome sequenced.

«Once we can build that sort of database for the human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the Genome Sequencing Center at Washington University in St. Louis.

The biggest effects of the genome sequence, according to the poll, have been advances in the tools of the trade: sequencing technologies and computational biology.

Today I'm working with scientists, physicians, and policy - makers on implementing new HIV testing strategies, evaluating the adoption of new hepatitis medications, and assessing the impact of genome sequencing in society.

With the imminent publication of the genome sequence of Homo neanderthalis, that question may finally be answered.

Accessing Ancient Genomes — New techniques and very old bones pushed back the limits of genome sequencing for our early ancestors.

New techniques and very old bones overcome the limits of genome sequencing for prehistoric horses, ancient cave bears, and even our own early ancestors.

In order to ensure that future antibiotics retain their effectiveness for as long as possible, it is essential that effective surveillance mechanisms are combined with the use of genome sequencing to scan for the emergence and spread of resistance.»

Bray says the falling cost of genome sequencing, plus portable monitors (such as Fitbit) to track in real time people's behavior and environment, mean that scientists already have the ability to collect the kinds of data they need to do the fundamental research behind precision weight loss.

But until recently, fungaria were of limited use for genetic research because of the technical complexity of genome sequencing and the poor quality of DNA samples obtained from old, dried specimens.

He is a pioneer of genome sequencing, but Harvard University's George Church wants to do more than read DNA.

This first draft of the genome sequence is a solid foundation for unlocking cotton's mysteries.»

They particularly support the interpretation of genome sequence data, which has become a powerful tool in many areas of biology and medicine in the last years.

As the cost of genome sequencing continues to drop, Jorde expects it to become part of standardized health care within a few years, making diagnostic tools such as Phevor more readily available to clinicians.

To overcome the extreme genomic complexity, the team used new long - read sequencing technology that boosted the quality of the genome sequence obtained by more than one hundred fold over standard short - read approaches.

With approximately 2.3 billion bases, the magnitude of the genome sequence of the Chinese hamster is comparable to that of the human genome.

Others, like futurist and tech guru Esther Dyson, are having parts of their genomes sequenced in a project led by geneticist George Church of Harvard University and MIT.

Up to 18 per cent of the genomes sequenced so far seem to be contaminated with human DNA, likely because of lax lab practices.

«No amount of genome sequencing would ever lead to a new medicine directly.»

Scientists can readily obtain extensive genetic information for any plant species of interest, at a relatively low cost, rapidly accelerating the pace of genome sequencing.

Massively parallel sequencing technologies, while increasing the speed, improving the accuracy, and reducing the cost of genome sequencing, typically produce only short stretches of sequences called «reads» After sequencing, the reads are pieced back together with genome assembly software.

With the decreasing cost and increasing efficiency of genome sequencing, he predicts that sequencing a cancer genome in a patient will soon become a standard of care, similar to an magnetic resonance imaging scan before surgery.

«We apologized for any distress experienced by the family as a result of our recent publication of the genome sequence of a HeLa cell line.

As a trend toward personalized medicine means that more people can have portions or the entirety of their genome sequenced, these results have implications for genetic counseling for infertility.

At the Joint Genome Institute (JGI) in Walnut Creek, CA, huge rooms full of genome sequencing machines work 24/7 to crunch the codes that create life.

Interpretation of genome sequencing data is a significant challenge because of the volume of genomic data to sift through, as well as the large, growing body of research on molecular drivers of cancer and potential targeted therapies.

5,831 Number of genome sequencing projects registered with the Genomes OnLine Database as of late 2009.

But that's the first step in a huge challenge — communicating the results of genome sequencing — one that BabySeq may help overcome.

Ten years ago in the early days of genome sequencing, researchers scoured the genomes of 580 bacterial and archaeal species for large genes.

«Our research highlights the enormous potential of genome sequencing to better understand biological processes and the fundamentals of biodiversity.

VectorBase will be responsible for the long - term curation of the genome sequence and subsequent annotation updates.

The grant, which came through the National Institutes of Health, mandates the publication of the genome sequence.

UNC clinical geneticists are part of a national consortium of researchers studying the ins and outs of genome sequencing for newborn health screenings and beyond.

We believe everyone should have the opportunity to contribute to research, especially now that the combination of genome sequencing and internet - based communication has made it easier to give people that opportunity.