«I'm quite confident that the current record of the genome
size of giant viruses will be broken,» he says.
A newfound
pair of giant viruses have massive genomes and the most complete resources for building proteins ever seen in the viral world.
But after discovering a novel
group of giant viruses with a more complete set of translation machinery genes than any other virus known to date, scientists at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, believe that this group (dubbed «Klosneuviruses») significantly increases our understanding of viral evolution.
The discovery in 2003
of giant viruses with hundreds or even thousands of genes shattered the existing definition of living organisms3.
A group
of giant viruses called Mimiviruses was first discovered in 2003, and a handful of such groups have been reported since.
Aside from increasing the known gene
pool of giant viruses by nearly 2,500 additional gene families, comparing the genes to previously discovered giant viruses revealed that the Klosneuviruses are a subfamily of Mimiviruses.
The unique ability among them to encode proteins involved in translation (typically DNA to RNA to protein) piqued researchers» interests as to the
origin of giant viruses.
In a study led by researchers at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, a new
group of giant viruses has been uncovered after sifting through complex genetic datasets.