Sentences with phrase «of glucose production»

During early fasting, the relative increase in whole body lipolytic rate was blunted in women compared with men, whereas the decline in the rate of glucose production was similar in both genders.»

When a hyperinsulinemic euglycemic clamp technique (200 pmol / L) was used, insulin - mediated suppression of glucose production and stimulation of glucose disposal did not differ significantly between the diets.

This fasting level of glucose production of about 600 calories per day is a key number: the body must obtain glucose at at least this level, either through diet or endogenous production, if it is to avoid a glucose deficiency.

Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter plasma concentrations of C - reactive protein, interleukin - 6, tumor necrosis factor alpha, and adiponectin; and did not significantly affect other risk factors for coronary heart disease (blood pressure and plasma glucose, insulin, and lipid concentrations) in either group.

Using experimental models and state - of - the - art technology, the scientists found that switching off this protein leads to better control of glucose production from the liver, revealing a potential new target that may be used to treat type 2 diabetes and other metabolic diseases.

Not exact matches

Besides glucose from complex carbs, essential fatty acids from whole foods like avocados are the «good» fats that are absolutely essential from your brain to run at its optimum level, helping with concentration, memory and overall production of that happy serotonin we all want high levels of.

Sweetener production of glucose, dextrose and high - fructose corn syrup would cover New Jersey.

Some of these hormones have other characteristics, such as anti-insulin properties, that decrease your body's sensitivity to insulin, increase glucose production, and can cause diabetes.»

Both galactose and glucose can also be used by the brain for energy, and galactose in particular is critical for the production of galactolipids (cerebroside), which are essential for the baby's developing central nervous system.

They regained healthy insulin production, reduced insulin resistance and demonstrated more stable levels of blood glucose.

Various studies have shown that high blood glucose levels stimulate the body's production of the enzyme.

The alteration radically increased the cells» dependence on glucose and glutamine, which are the raw materials of viral production.

To determine how fat might alter glucose uptake, the researchers measured the production of blood - borne molecules that fat cells secrete.

In addition, the researchers observed that adiponectin regulated the production of glucose by rat liver cells — suggesting that the hormone helps suppress the release of sugar stores.

The scientists found that both the activity of the genes, as well as the production of the cholera toxin itself were increased when the bacterium was fed with glucose, but they were considerably decreased when it was fed with starch from rice.

The report indicates that Sestrin 3 plays a critical role in regulating molecular pathways that control the production of glucose and insulin sensitivity in the liver, making it a logical target for drug development for type 2 diabetes and metabolic syndrome, which can produce increased blood pressure, abnormal cholesterol levels and insulin resistance.

«Although it has long been recognized that a key event leading to development of type 2 diabetes is uncontrolled glucose production from the liver, underlying mechanisms have been elusive,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and J.S. Simmons Professor of Genetics and Metabolism at HSPH.

What's more, loss of the protein hampers two adjustments — increased glucose intake and protein production — that help cancer cells maintain their rapid division, the team found.

Insufficient production of insulin leads to an accumulation of glucose in the blood, and can cause Type 1 diabetes.

But that production stops after a meal, when insulin is released by the pancreas and performs its main task of removing sugar from the blood and shepherding the glucose to multiple types of cells that absorb it for energy.

This triggers the production of insulin, which in turn acts to lower blood glucose levels.

Norbert Stefan, the first author of the article, proposes that «after initial classification of the glucose categories NGR and prediabetes, fatty liver, visceral obesity and impaired production and action of insulin should be included in assessment of cardiometabolic risk.

The relevance to account for the major pathophysiological mechanisms of diabetes can be observed that in diabetes diagnosed by elevated fasting or 2 hr glucose levels during a standard oral glucose tolerance test (OGTT) the prevalence and the sequence of appearance of impaired insulin production and impaired insulin secretion differ.

These trends may be explained in part by the yo - yo effects that high glycemic - index carbohydrates have on blood glucose, which can stimulate fat production and inflammation, increase overall caloric intake and lower insulin sensitivity, says David Ludwig, director of the obesity program at Children's Hospital Boston.

The gene blocks the production of ADP - glucose pyrophosphorylase, an enzyme which converts sucrose into starch in tubers.

Molecules produced by some of the bacteria may increase glucose production in the body and push blood glucose levels out of balance, the researchers suggest.

In one example, the research team put the production of an antidiabetes peptide in mice under the control of an optogenetic switch, allowing them to regulate glucose levels in the animals just by shining light on them.

«We have identified a novel pathway for suppression of liver glucose production that could be used to compensate for the loss of naturally occurring CST or to bolster its impact.

The action of TZDs on adipose tissue macrophages may decrease local production and concentrations of proinflammatory factors and thereby contribute to their physiologically beneficial effects on glucose and lipid metabolism.

«We have shown that an endogenous peptide, catestatin, can directly suppress glucose production from hepatocytes and can indirectly suppress lipid accumulation in liver as well as macrophage - mediated inflammation in obese mice,» said Sushil K. Mahata, PhD, professor of medicine at UC San Diego School of Medicine.

12 - mo - old Tg mice displayed extensive islet pathology and overt signs of T2D, including massive amyloid deposits, impaired insulin production (Fig. 1) and severe hyperglycemia (> 360 mg / dl fasting blood glucose).

Blood samples showed that many in this group exhibit C - peptide molecules (a marker of insulin production), blood glucose levels that rise less after a meal than would be expected in the absence of insulin, and signs of autoimmune attack.

Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin - like growth factors.

Metformin exerts its major effect via inhibition of hepatic glucose production.

From the perspective of a bioengineer interested in converting glucose input into lipid output, the development of a thicker cell wall under starvation conditions represents wasted carbon that would otherwise be used for lipid production.

This means that increased levels of ZAG in patients may indicate a system - wide mobilization of lipids for energy production, particularly because these individuals lack endogenous insulin and can not rely on blood glucose (sugar) for their energy needs.

The research describes how a combination of glucose uptake and mitochondrial pyruvate import allow a specific type of plasma cell to sustain durable antibody production.

In fact, the rates of insulin infusion required to maintain basal hepatic glucose production in the presence of pancreatic clamp were 0.75 + / -0.10, 1.41 + / -0.13, and 0.51 + / -0.12 mU / kg.

Unlike in type 1 diabetes, in which insulin production is limited because beta cells are destroyed, «arsenic induces glucose intolerance through a disruption of beta - cell function that alters normal stimulus — secretion coupling,» the researchers wrote.

By contrast, the sensitivity of the maternal liver to insulin was increased, which reduces glucose production during pregnancy.

«The efficient production of endoderm represents the first critical step in the creation of a renewable islet source derived from hES cells that is targeted at restoring normal glucose regulation in diabetic patients.»

Both obese humans and mice have significantly elevated soluble Fabp4 / aP2 levels, and injection of recombinant Fabp4 / aP2 into lean wild type mice stimulates hepatic glucose production and gluconeogenesis.

The job of testosterone is to promote protein synthesis and support production of new red blood cells, which increase the body's ability to utilize oxygen more effectively, which then leads to more efficient usage of glucose.

In a 2010 study, researchers found a link between dietary sugars like glucose and greater production of advanced glycation end products (AGES).

When the adrenal gland produces adrenaline and the adrenaline (beta - adrenergic) receptor communicates with the G - protein and its signal cascade, the parts of the body are alerted to the need for action; the heart beats faster, the blood flow to the gut decreases while the blood flow to the muscles increases and the production of glucose is stimulated.

Diabetes is a condition where the blood glucose levels are at a constant peak as the body's cells can't absorb it because of lowered or non-existent insulin production or because insulin is unable to help with the absorption of glucose.

For most of your meals, especially the pre-workout one, it's best to aim for slow - digesting natural carbs such as rice, beans and yams that produce slow increases in blood glucose and insulin production, providing a steady supply of energy during your workout or any other type of activity.

For example, if you're having a huge fight with your partner and he / she threatens to leave you, your body will react on the same way it would if you were in the middle of an earthquake — the heart starts racing, the blood vessels dilate and increase the amount of blood pumped to large muscles, the muscles tense up and your endocrine system increases the production of cortisol and epinephrine, which then influence the liver to produce more glucose and provide energy for an efficient «fight or flight» reaction to the dangerous situation.

And eating too much protein isn't the best substitute since anything above 0.6 - 0.8 grams of protein per pound of bodyweight will actually lead to the production of enough glucose that will take your body out of ketosis.

Now, when your brain's production of insulin decreases, your brain literally begins to starve, as it's deprived of the glucose - converted energy it needs to function normally.This is what happens to Alzheimer's patients — portions of their brain start to atrophy, or starve, leading to impaired functioning and eventual loss of memory, speech, movement, and personality.