Sentences with phrase «of glucose to the cells»

As a result, your pancreas starts pumping out more insulin, which is responsible for the transport of glucose to the cells, where it is either stored as fat, or burned as a fuel.

The muscle cells build up a resistance to insulin, so the body produces more and more in an attempt to maintain the transport of glucose to the cells for energy.

Pancreas releases insulin to provide steady flow of glucose to the cells.

I now understand how my amazing body works to keep an even stream of glucose to my cells, so they can covert it to energy.

It is our speculation by maintaining high insulin sensitivity, when carbohydrates are brought back during competition the slight insulin response actually speeds delivery of glucose to cells and conversion of glucose to ATP without seriously impacting high level fat metabolism.

The symptoms of diabetes, however subtle or apparent, are caused by both the reduction in the delivery of glucose to the cells and the elevated blood levels of glucose that is unused.

Not exact matches

Increased ability to burn fat: Research shows that cold - induced glucose uptake results in the creation of brown fat cells, which create warmth, burn energy and keep you slim.

These vitamins have a variety of functions that help maintain a healthy body - to metabolize carbohydrates and maintain blood glucose levels, fatty acids for energy, and they help make hemoglobin, the red and white blood cells.

For a long time, insulin was not thought to play a direct role in regulating the milk - making cells of the human breast, because insulin is not needed for these cells to take in sugars, such as glucose.

Insulin resistant cells are less able to convert glucose into energy, resulting in a peak of blood glucose after eating a meal which goes through the placenta to «feed» the baby.

The researchers also found that human corneal cells exposed to high levels of glucose showed less response to an electric field.

Using an MRI technique that is sensitive to certain byproducts of cell metabolism, including levels of glucose and acidity, University of Iowa researchers discovered previously unrecognized differences in the brains of patients with bipolar disorder.

It is a smart filter at that: The cells lining the brain's blood vessels can build extra proteins for grabbing glucose if the brain needs a boost and can also destroy some of the proteins to dial the flow back down.

«That observation is in line with the usual response of cells to oxygen deprivation: they save on the consumption of oxygen by converting glucose to lactate instead of burning the glucose.

Schwarz and her colleagues used three different drugs, alone and in combination, to deprive cervical tumors of glucose and block downstream metabolic pathways that help protect cancer cells from building up toxic free radicals.

One of the cell lines was vulnerable to being cut off from glucose alone, but the others needed more interference.

To find it, the scientists injected the eight tumor - bearing mice with high levels of labeled glutamine and glucose, another metabolic compound commonly linked to the growth of pancreatic cancer cellTo find it, the scientists injected the eight tumor - bearing mice with high levels of labeled glutamine and glucose, another metabolic compound commonly linked to the growth of pancreatic cancer cellto the growth of pancreatic cancer cells.

This leads to high blood glucose values; the function of the insulin - producing cells in the pancreas is also negatively influenced.

Witness Avandia, a popular drug available since 1999 that lowers blood glucose by making cells more receptive to insulin — but that also, according to a report published in the New England Journal of Medicine in May, increases the risk of heart attack.

«Our stem cell - based studies indicate that low - calorie sweeteners promote additional fat accumulation within cells compared with cells not exposed to these substances, in a dose - dependent fashion — meaning that as the dose of sucralose is increased more cells showed increased fat droplet accumulation,» said Sabyasachi Sen, M.D., Associate Professor of Medicine at George Washington University in Washington, D.C. «This most likely occurs by increasing glucose entry into cells through increased activity of genes called glucose transporters.»

Most importantly, these cells protected mice from developing diabetes in a model of disease, having the critical ability to produce insulin in response to changes in glucose levels.

Dr Matthew Hobbs, Head of Research for Diabetes UK, said: «We know that preserving or restoring even relatively small levels of insulin secretion in Type 1 diabetes can prevent hypoglycaemia (low glucose levels) and reduce complications and therefore much research has focused on ways to make new cells that can be transplanted into the body.

Because older red blood cells have had more time to pick up sugar in the blood, they can potentially skew the A1C test result, which averages glucose across red blood cells of all ages in the bloodstream.

To develop a more accurate method, Higgins and colleagues designed a mathematical model of glucose chemistry and red blood cell turnover and combined it with large data sets of patient glucose measurements.

Only when astrocyte function was restored did the gastric grumbles return, showing that it is these cells that respond to low glucose levels (Journal of Neuroscience, DOI: 10.1523 / JNEUROSCI.1406 - 14.2014).

To determine the age of the blood cells, Higgins and his colleagues developed an equation that compares glucose levels obtained by the A1C test with another method called continuous glucose monitoring.

The stress this places on cells leads to the overproduction of glucose, which when not used for energy transforms into lactic acid, which is difficult for the body to flush out.

Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a meal.

The cells enlarge, develop complex elements that enable them to contract, and switch from a metabolism that depends on glucose for most of its energy to a metabolism that derives most of its energy from fats.

Increasing the expression of one of the proteins, SIX3, in the insulin - producing cells isolated from younger donors enhanced their ability to respond efficiently to rising glucose levels.

But excessive sugar is toxic to cells, so after years of glucose and insulin overload, the cells can become insulin resistant and may no longer allow insulin to easily push glucose inside them.

Studies in rodents and in human fetal beta cells have showed that the responses of very young beta cells to increases in blood glucose are blunted when compared to their more - mature counterparts.

Biomolecular model based on the gene expression data analyses support the reduction of glucose molecules (blue gradient) and acid buildup (gold gradient) proposed to occur in the boundary layer around the cell.

«In the study we challenged the view that the age - dependent impairment in glucose homeostasis is solely due to intrinsic, dysfunction of islet cells, and hypothesized that it is instead affected by systemic aging factors,» says first author Joana Almaca at the Diabetes Research Institute, University of Miami.

«We found that expression of glucose transporters is completely shut down by bacteria, leaving insufficient fuel for the immune cells to fight off the infection,» said the study's first author, Subramanian Krishnan, PhD, of the Division of Infectious Diseases at CHLA.

Medicines used to treat diabetes fall into four groups: those that stimulate the pancreas to put out more insulin; those that lower insulin resistance in cells; those that help the body use insulin; and those that slow down or block the breakdown of starches, which in turn keeps blood - glucose levels lower.

Even a small number of functioning, insulin - producing cells can restore hypoglycemic awareness, although transplant recipients may need to continue taking insulin to fully regulate blood glucose levels.

Another method is for cells to throttle back the processing of glucose during lean times by becoming insulin resistant, which blocks insulin from entering the cell and in essence rations the supply of glucose to last longer while also creating a powerful hunger impulse to drive people to find food.

To determine how fat might alter glucose uptake, the researchers measured the production of blood - borne molecules that fat cells secrete.

Aware that cancers rewire their metabolism in ways that could change the epigenome and that distant metastases in pancreatic cancer naturally spread to organs fed by a sugar - rich blood supply, the researchers wondered if the tumor cells had altered the way they use the basic form of sugar, glucose.

Last summer, Gerald Shulman of Yale University and the Howard Hughes Medical Institute implicated mitochondria — the parts of the cell that burn fat and glucose to produce energy.

«We hypothesize that older humans might be especially susceptible to the effects of sleep deprivation on the disruption of glucose homeostasis via cell stress.»

But when Morono's team treated the cells to what he calls a «luxury meal» of glucose and other nutrients, most of them incorporated some food — suggesting that they are, in fact, alive.

From the first day of transplantation, the cells produced insulin in response to glucose spikes in the mice's blood, alleviating the modeled diabetes.

There is no question that ability to generate glucose - responsive, human beta cells through controlled differentiation of stem cells will accelerate the development of new therapeutics.

Cantley's lab and collaborators found that large doses of vitamin C did indeed kill cultured colon cancer cells with BRAF or KRAS mutations by raising free radical levels, which in turn inactivate an enzyme needed to metabolize glucose, depriving the cells of energy.

«We suspect this communication system between adipose tissue and liver may have evolved to help fat cells command the liver to supply the body with glucose in times of nutrient deprivation.

The transporter, GLUT1, supplies the cells with the high levels of glucose they need to survive.

The U-M study explains how increased cAMP in fat cells promotes the secretion of the hormone interleukin - 6, which signals the liver to stop producing glucose — thus improving overall blood sugar levels in obese diabetic mice.

But that production stops after a meal, when insulin is released by the pancreas and performs its main task of removing sugar from the blood and shepherding the glucose to multiple types of cells that absorb it for energy.