And in an ad lib setting, «Laboratory studies in healthy young volunteers have shown that experimental sleep restriction is associated with a dysregulation of the neuroendocrine control of appetite consistent with increased hunger and with alterations in parameters
of glucose tolerance suggestive of an increased risk of diabetes» (Van Cauter et al., 2007).
Therefore, the hyperinsulinemia registered in vivo and in vitro, associated with the impairment
of glucose tolerance and the decrease in AKT phosphorylation, make clear the occurrence of peripheral insulin resistance.
The trace element chromium is an essential component
of glucose tolerance.
20g carbs for years and now my DHEA and sex hormones are very low and I have insulin resistance - getting into the 300s at the 3rd hour
of a glucose tolerance test.
The difference in peak glucose levels in response to breakfast averaged was large enough to suggest a clinically significant impairment
of glucose tolerance.
Another reason I prefer this is that it is a more comprehensive view
of glucose tolerance and I even get to see what foods cause higher spikes for me personally and which don't affect it as much at all.
When compared with a control group, the arsenic - exposed mice exhibited higher blood glucose levels due to reduced insulin secretion during the early phases
of a glucose tolerance test.
Impact
of glucose tolerance status, sex, and body size on glucose absorption patterns during OGTTs
With age - induced deterioration
of glucose tolerance, sex differences are reduced, leading to more pronounced aggravation of the metabolic profile in women than in men (206, 207).
Glucose tolerance at age 58 and the decline
of glucose tolerance in comparison with age 50 in people prenatally exposed to the Dutch famine
Gender effect on insulin sensitivity and secretion in different categories
of glucose tolerance
Following our detailed assessments
of glucose tolerance, insulin sensitivity, blood pressure and musculoskeletal investigations we found that our clones, considering their age, were at the time of our research healthy.»
Since cavefish aren't a well - studied model for human metabolism, the researchers had to figure out protocols as they went, including developing a fish version
of a glucose tolerance test.
Not exact matches
Lactis 420 (B420 ™) Reduces Weight Gain and Improves
Glucose Tolerance, Thereby Counteracting the Adverse Effects
of a High - fat Diet in Mice.
Tests for diabetes and its precursor, impaired
glucose tolerance, check how well the body uses
glucose, a type
of sugar.
«Women really hate to get tested» with the oral
glucose tolerance test, said Dr. Michael Traub
of the Albert Einstein College
of Medicine in New York, who worked on the study.
If your results indicate high insulin levels, you'll undergo a second test called the
glucose tolerance test, which involves fasting, a higher intake
of glucose, and several blood draws.
Nearly half have impaired
glucose tolerance and ten percent will develop diabetes by the age
of 40.
By day five, four
of the seven people had a significant decrease in their
glucose tolerance, while three saw no change.
Moreover, removal
of TAK1 from mice that had previously been fed a high fat diet prevented additional weight gain and improved
glucose tolerance.
A total
of 13 healthy pregnant women underwent an oral
glucose tolerance test (75 g
of glucose delivered orally, a standard method for determining insulin sensitivity).
Thirty minutes later they consumed a drink containing 75 grams
of sugar (i.e., a standard oral
glucose tolerance test).
At four months postpartum, the mice that were exposed to BPA began to show signs
of impaired
glucose tolerance.
estrogen administration to post-menopausal female mice led the Geneva scientists to make a first observation: they identified an increased
tolerance to
glucose, which is correlated to a lower risk
of diabetes.
In humans,
glucose tolerance varies with time
of day, but the mechanism responsible for the variation in insulin sensitivity throughout the day is unclear.
The relevance to account for the major pathophysiological mechanisms
of diabetes can be observed that in diabetes diagnosed by elevated fasting or 2 hr
glucose levels during a standard oral
glucose tolerance test (OGTT) the prevalence and the sequence
of appearance
of impaired insulin production and impaired insulin secretion differ.
«What we show is that inhibiting IDE in an animal can improve
glucose tolerance under conditions that mimic the intake
of a meal if you administer this compound beforehand.»
This variability in the prevalence
of these risk phenotypes can already be observed in the prediabetic states isolated impaired fasting
glucose (IFG), isolated impaired
glucose tolerance (IGT) or IFG+IGT combined.
Using mice fed on a fat - rich diet that made them overweight and raised their blood sugar levels, they found that a daily dose
of kynurenic acid stopped the mice putting on weight and gave them better
glucose tolerance, despite no change in their food intake.
«We also showed that this profound effect was dose - dependent with better
glucose tolerance achieved through higher doses
of butein,» Dr Tups says.
The improved
glucose tolerance of high - fat diet mice treated with the antioxidant was such that no difference was noticeable between them and low fat - diet mice that had not received butein.
The body weights, food intake,
glucose tolerance and insulin sensitivity
of all the mice were tracked.
Pulsing blue light upon the mice for 48 hours led to an increase in the rodents» insulin levels and better
tolerance of glucose compared with control mice.
A total
of 105 older (average age 61 years), overweight or obese individuals with impaired
glucose tolerance or type 2 diabetes mellitus (T2DM) participated in a 12 - to 16 - week period
of aerobic exercise training.
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in
glucose and insulin
tolerance and reduced body weight, report University
of California San Diego School
of Medicine researchers.
In our studies, we observed hyperglycemia and impaired
glucose tolerance in the Tg - hIAPP mice treated with IAPP aggregates, which occurred concomitant to a significant loss
of β cells (> 60 %).
Interestingly, associated to IAPP accumulation, animals developed some
of the typical clinical abnormalities
of T2D, including hyperglycemia, impaired
glucose tolerance, and loss
of β cells.
At the onset
of the study, all participants were overweight and had impaired
glucose tolerance.
Importantly, intraperitoneal inoculation
of pancreatic homogenates containing IAPP aggregates into transgenic mice expressing human IAPP dramatically accelerates IAPP amyloid deposition, which was accompanied by clinical abnormalities typical
of T2D, including hyperglycemia, impaired
glucose tolerance, and a substantial reduction on β cell number and mass.
Metabolic Phenotyping: The Mouse Metabolic Phenotyping Center (MMPC) at Case Western Reserve University specializes in hyperinsulinemic euglycemic
glucose clamps,
glucose tolerance tests, total energy expenditure at rest and exercise, lipid or collagen turnover studies utilizing the incorporation
of 2H from 2H - enriched body water, feeding studies, acute or chronic vascular catheterization, activity monitoring, etc..
The
glucose levels also were similar to those
of people with the impaired
glucose tolerance that leads toward type 2 diabetes.
Oligomeric cocoa procyanidins possess enhanced bioactivity compared to monomeric and polymeric cocoa procyanidins for preventing the development
of obesity, insulin resistance, and impaired
glucose tolerance during high - fat feeding.
Glucose tolerance deteriorates the increase
of MYCL, which was more pronounced in women, abrogating sex differences in T2DM.
Deficiency
of Fc?R1 Increases Body Weight Gain but Improves
Glucose Tolerance in Diet - Induced Obese Mice.
It further highlights the importance
of performing oral
glucose tolerance tests to screen for IGT, especially in women.
Interestingly, choline deficiency in the context
of a lard - based HFD (45 %
of calories) was shown to improve
glucose tolerance compared to the choline suffcient group in mice (18).
Superior
Glucose Tolerance and Metabolomic Profiles, Independent
of Adiposity, in HIV - Infected Women Compared With Men on Antiretroviral Therapy.
Glucose tolerance and the amount
of excess insulin circulating in the blood improved.
Background: WNIN / Gr - Ob rats demonstrate features
of metabolic syndrome that include obesity, insulin resistance, impaired
glucose tolerance, and hyperinsulinemia.
Prevalence
of diabetes, impaired fasting
glucose, and impaired
glucose tolerance in U.S. adults.