Sentences with phrase «of gonadal»

Because neutering can be expected to disrupt the normal physiological developmental role of gonadal hormones on multiple organ systems, one can envision the occurrence of disease syndromes, including those listed below, to possibly be affected by neutering as a function of gender and the age at which neutering is performed.

The striking effect of neutering in female Golden Retrievers compared to male and female Labradors, and male Golden Retrievers, suggests that for this gender and breed the presence of gonadal hormones has a protective effect against cancers over most years of the dog's life.

For some cancers of interest, not only may breeds vary in predisposition but also the possibility of interactions between gender, gonadal hormone influences, and timing of gonadal hormone alteration should be taken into account in selecting the model and in investigating causal factors to be explored.

Given the importance of gonadal hormones in growth and development, this cultural contrast invites an analysis of the multiple organ systems that may be adversely affected by neutering.

While the study set out to estimate incidence rates of each disease related to age at neutering, patients were diagnosed at different ages and with differing durations of the disease as well as varying years at risk from the effects of gonadal hormone removal.

These subgroups included two biologically distinct groups representing the extremes of gonadal hormone exposure (i.e., dogs neutered before skeletal maturation at < 1 year of age and dogs that remained sexually intact for their entire lifetime).

We analyzed risk for bone sarcoma using months of gonadal hormone exposure as a continuous variable.

This stratification enabled us to evaluate the dose - response relationship between duration of gonadal exposure and bone sarcoma risk within the study cohort.

Because the database used in that study provided no information on age at gonadectomy, the study could not evaluate bone sarcoma risk in terms of duration of gonadal hormone exposure.

Lifetime gonadal hormone exposure of each dog was expressed in terms of total months of gonadal hormone exposure (i.e., number of months sexually intact).

In the researchers» own words: «our data show that at the level of gonadal gene responses, the male rats on the IF regime adapt to their environment in a manner that is expected to increase the probability of eventual fertilization of females that the males predict are likely to be sub-fertile due to their perception of a food deficient environment.»

This is in agreement with findings in juvenile male and female rats with low levels of gonadal hormones.

Cooke will receive the award over the next five years to study how rising levels of gonadal hormones, such as testosterone and estrogen, change behavior, motivation and perception during puberty.

The daughter's gonads were also examined after surgery and exhibited an early form of gonadal cancer.

Even worse, the tissue defects in the original patient identified with this mutation also contribute to the development of gonadal cancer.

Bloch, M., Schmidt, P. J., Danaceau, M., Murphy, J., Nieman, L., and Rubinow, D. R. Effects of gonadal steroids in women with a history of postpartum depression.

Not exact matches

Studies at Bellevue have shown that disturbances or deficiencies of the pituitary - adrenal - gonadal triad of endocrine glands are present in many alcoholics.

The SRY (sex - determining region Y) gene on the male's Y chromosome orchestrates the formation of the testes, while the gonadal precursor will differentiate into an ovary by default (in the absence of the steroids produced by the testes).

If gonadal hormones alone control sex - specific brain function, the two halves of the bird's brain that controls song (known as the song circuit) would be uniformly masculine or feminine.

The experience can alter parts of the brain which in turn control the production of hormones (known as gonadotropin - releasing hormones, or GnRH) which then regulate gonadal (testicular) development.

Ninety percent of germ cell tumors are gonadal, which means they begin in the reproductive cells of the testes or ovaries.

I study the gonadal steroid regulation of neural circuits that control reproductive behavior, and the physiology and function of steroids made in the brain (neurosteroids).

In view of the different timing of meiotic initiation in female and male mammals, we determined the developmental expression profile of mouse Boule during both male and female embryonic gonadal development (embryonic day 10.5, E12.5, E16.5 and E17.5) in comparison with adult gonads.

RT - PCR analysis of RNA from mouse embryonic and adult gonads using primers corresponding to either exons 3 and 9 (upper panel, 501 - bp band) or exons 3 and 12 (lower panel, 847 - bp and 712 - bp bands) reveals that full - length Bol1 is only expressed in postnatal testes, while Bol2 lacking exon 11 is also detectable at low levels throughout gonadal development in addition to its high adult testis expression.

Chicken gonadal and other tissues were collected from euthanized White leghorn chickens at the completion of a research project approved by UIUC animal committee at the University of Illinois at Urbana - Champaign Veterinary School.

The effects of extrinsic factors was examined using gonadal conditioned media or several growth factors for germ cell differentiation in vitro in monkeys.

Beyond that, high perceived stress strongly affects the control system of most hormones, which is the brain / body system known as the hypothalamic - pituitary - adrenal - thyroid - gonadal (HPATG) axis.

There are issues that can occur with the adrenals, hypothalamic / pituitary / gonadal (ovarian) axis, and with the ovaries specifically, that could elevate testosterone levels without the presence of PCOS.

Evaluation of the entire hypothalamic - pituitary - gonadal (ovarian) axis may help also.

These findings suggest that variations in gonadal hormones during the menstrual cycle influence the experience of pain in healthy women.»)

Research performed on human males with androgen insensitivity syndrome compared to the classical sexual development models which were created from research on rats, indicates that the rat model does not account for the sensitivity of the hypothalamal - hypophyseal - gonadal axis with fluctuations in hormonal levels, namely androgens and estrogens.7

4) Reduces the function of Estrogen Receptor Beta 5) Negatively affects mitochondrial function 6) Alters hypothalamic pituitary - gonadal axis Increases testosterone, 7) lowers progesterone, 8) alters GnRH secretion 9) Increases glucocorticoids, 10) heightens response to stress, elevates levels of anxiety

Review biological implications of hormone imbalance (thyroid, gonadal, adrenal, and other hormone systems).

Instead, vitex has an effect on the hypothalamic - pituitary - gonadal axis (a feedback loop) where it interacts with the anterior pituitary gland and reduces its secretion of prolactin.

But some things to consider: a) the dose of your thyroid medication might need to be adjusted based on the symptoms of heart palpitations; b) there are many possible reasons that your testosterone level is low (e.g.: nutrient deficiencies, adrenal gland stress, hypothalamic / pituitary / gonadal axis dysfunction, liver dysfunction, etc.), and c) your thyroid may not be functioning optimally despite being on thyroid hormone.

Your endocrine pathway starts with the hypothalamus, affecting your pituitary, which in turn affects the function of your thyroid, then adrenals, gonadal hormones, and finally gut.

Sarah Ballantyne, PhD., author of The Paleo Approach, will discuss how an ancestral diet can affect the Hypothalamus - Pituitary - Adrenal / Gonadal / Thyroid axis differently in women versus men.

Women on hormonal birth control generally have inhibited function of their hypothalamic - pituitary - gonadal axis, causing suppressed estrogen and progesterone levels.

Pituitary - gonadal hormonal responses of multi-set vs. single - set resistance training.

Also, a missing period is a symptom of more intricate problems related to the hypothalamus, pituitary and gonadal function.

D - aspartic acid d - Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo - pituitary - gonadal axis in resistance - trained men http://www.nrjournal.com/article/S0271-5317 (13) 00173 - 5 / abstract

In today's high - stress, high - inflammatory world, I see this frequently and it's usually as a result of a suppressed HPG (hypothalamus, pituitary, gonadal) communication pathway.

Sertoli - Leydig cell tumors are members of the sex cord gonadal stromal tumor groups (tumors of sex cord derived tissues) of ovarian neoplasm.

For males, the gonadal exposure subgroups were: castrated before 1 year of age; castrated between 1 and 3.5 years of age; castrated after 3.5 years of age; and sexually intact.

For females, the gonadal hormone exposure subgroups were: spayed before 1 year of age; spayed between 1 and 5 years of age; spayed after 5 years of age; and sexually intact.

The possible mechanisms by which gonadal hormone exposure might protect against the development of bone sarcoma in both males and females are not immediately evident.

To determine whether there was an association between endogenous sex hormones and risk of bone sarcoma, relative risk (RR) of incidence rates and hazard ratios for bone sarcoma were calculated for dogs subdivided on the basis of lifetime gonadal hormone exposure.

However, in that study, age at neutering was not available, and thus, duration of exposure to gonadal hormones for each dog could not be determined.

This analysis was also deemed logical for pathophysiological reasons because a disruption of the growth plate closure by gonadal hormone removal in the joint developmental stage would be expected to apply to all the joint disorders.

Differences in the two breeds studied here could be due to differences in sensitivities of the growth plates to gonadal hormone removal.