Sentences with phrase «of gut»

We know that a well - balanced gut microbiota is critical for maintaining general health, and alterations in the composition of gut microbiota have been linked to a range of disorders.»

«Early life exposure to lead causes a long lasting impact on gut microbiome, and the change of gut microbiome may partially contribute to the increased body weight in adult life,» said lead author Chuanwu Xi, associate professor of environmental health science.

«Remarkably, our findings suggest that composition of the gut microbiota influence and alter central carbon metabolism in a genotype independent manner.

Esrp1 and Esrp2 are active specifically in epithelial cells, which form the skin, the inner layers of the gut and lung, and other tissues in the body.

Deleting telomere elongation capacity throughout the body would also be life - threatening, because it would mean that our regular proliferating cells (like those in the skin or the lining of the gut) would suddenly have iron limits on their ability to reproduce themselves and thus replenish tissue.

Because the lining of the gut, a prime meeting point between the inside of the body and the hazards of the outside world, is a headquarters of the immune system, the vigilance may help the child's immune defenses develop.

While scientists have made great progress in identifying the individual members of the gut microbiome, it's much harder to determine exactly what they do — both individually and in concert with other microbes.

He notes, however, that researchers need to develop more rigorous ways to test the role of the gut microbiome in controlling immune reactions.

Now researchers have made the first study of the thanatomicrobiome — the army of gut microbes that take over your internal organs once you are dead.

By watching a capsule pass through the gut with an ultrasound, the researchers found that oxygen concentrations varied in different regions of the gut, for example between the stomach and the small intestine.

But help may be on the way: Scientists report in next month's issue of Nature Medicine that rats unable to digest lactose, a sugar in dairy foods, are cured by a pill that stitches new genes into the cells of the gut.

Antibiotic treatment reduced motor deficits and molecular hallmarks of Parkinson's disease in a mouse model, whereas transplantation of gut microbes from patients with Parkinson's disease exacerbated symptoms in these mice.

«Precision editing of gut bacteria: Potential way to treat colitis.»

A new study finds that members of a common class of gut bacteria, Clostridia, can counter sensitivity to peanuts.

Alarmones are molecules that bacteria produce in response to extreme environments, such as in the harsh environment of the gut.

Changes in the composition of the gut microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.

Animals in each of the three groups — gastric bypass, sham surgery, and restricted diets — were killed and samples of their gut microbe communities diluted.

Bode believes these sugars, because they are indigestible, journey intact to the colon, where their structure mimics molecules on the surface of gut epithelial cells.

To test their idea, they raised the hybrid offspring of N. vitripennis and each of the other wasp species in a germ - free environment, eliminating any signs of gut bacteria that might be toxic to the wasps.

One of the main hurdles in understanding the biology of the gut microbiota is its vast diversity.

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Nutritional scientist Lars Bode believes the compound may act by encouraging the growth of beneficial bacteria or by reducing inflammation of the gut.

The big step forward, Cummings says, is what the researchers did next: They performed a series of gut microbe transplants.

Along with a postdoc in Kaplan's lab, Alice Liou, they decided to test whether the surgery itself caused the changes in the population of gut microbes — known as the microbiota.

In recent years, there has been an explosion of interest in the role of the gut microbiome in the development of type 2 diabetes and obesity.

By contrast, mice raised in the germ - free cages showed worse motor symptoms when they either were treated with microbial metabolites called short - chain fatty acids or received fecal transplants of gut microbes from patients with Parkinson's disease.

Specifically, they knew two closely related wasp species, Nasonia giraulti and Nasonia longicornis, could produce healthy hybrid offspring and that the two had a similar array of gut bacteria.

«Like zebrafish, we have this rich source of gut microbes that have figured out how to coexist with us and soothe the immune system,» she says, adding that «there is enormous potential to harness those mechanisms» to address ailments such as inflammatory bowel disease and other chronic inflammation.

«Several studies have detected differences in the composition of the gut microbiome between healthy people and those with obesity and type 2 diabetes, but the cause and effect remain unclear,» says Mark McCarthy, and continues:

The effect of gut microbiome on tolerance to morphine mediated antinociception in mice.

But more work needs to be done, and at least one major question needs answering: Do people with relapsing - remitting MS have a different set of gut bacteria than people with the primary progressive form of the disease?

We examined 13,355 prokaryotic ribosomal RNA gene sequences from multiple colonic mucosal sites and feces of healthy subjects to improve our understanding of gut microbial diversity.

«A reduction in the diversity of the gut's microbiota and a loss of some of the beneficial biota is clearly not a good thing for health.»

«We don't completely understand why those species occur during cholera infection, but that phenomenon may offer clues as to why we observe different species of gut bacteria among humans in different parts of the world.

Having the wrong kind of gut bugs might help cause type - 1 diabetes.

But now researchers have developed a technique to get a better census of the gut microbiome.

Meanwhile, other new work is also shedding light on how we acquire the specific menagerie of gut creatures, including our interactions with the environment, the people around us and genetics.

Before the regime, Enterobacter — a toxin - producing pathogen — was most abundant, accounting for 35 per cent of the gut bacteria.

Embedded in the wall of the gut, the enteric nervous system (ENS) has long been known to control digestion.

Changes in the composition and activity of the gut microbiome in early life can influence the immune system and these changes might indirectly lead to changes in asthma later in life,» said Dr. Anke Maitland - van der Zee, senior author of the study.

It can work both independently of and in conjunction with the brain in your head and, although you are not conscious of your gut «thinking», the ENS helps you sense environmental threats, and then influences your response.

That's the tantalizing finding from a new study published today that reveals a way that mice — and potentially humans — can control the makeup and behavior of their gut microbiome.

For instance, the presence or absence of gut bacteria can influence whether a mouse exhibits anxiety - like behaviors, such as avoiding bright lights or open spaces.

WE HAVE all experienced the influence of gut bacteria on our emotions.

While further research is needed to confirm the identity of the cancer - promoting bacteria, the findings suggest it may be possible to reduce the risk of colorectal cancer in genetically susceptible individuals by removing certain types of gut bacteria.

Severance says they plan to take their studies of the gut - brain connection into mouse models to test for a cause - and effect - relationship with Candida and memory deficits.

The hipster insects serve up beneficial bacteria that may help baby bees develop a healthy blend of gut microbes, researchers report online August 7 in Applied and Environmental Microbiology.

Because both of the new studies transplanted the entire community of gut bacteria from people into mice, they couldn't show which particular bugs played necessary or sufficient roles in MS.

But a better understanding of the gut environment will be necessary to achieve the next level of advances in comprehending the disease and fashioning better interventions, researchers said last Wednesday at the annual Conference on Retroviruses and Opportunistic Infections in Boston.

«Although we don't know the mechanisms yet, repopulation of the gut by bacteria appears to analogous to succession in a forest after it is damaged in a storm,» said microbiologist David Berry: «pioneer species colonize the deforested area, in this case the inflamed intestine, and alter the ecosystem in a way that lets other species colonize and eventually a complex ecosystem can be restored.»