Sentences with phrase «of gut epithelial cells»

The body's own immune system attacks the cells that line the small intestine, resulting in the characteristic shortening or pruning of the intestinal villi (microscopic, finger - like projections of small intestine wall tissue made of columns of gut epithelial cells).

Because it means they have the ability to penetrate cells lining the digestive tract and cause a loss of gut epithelial cells.

Bode believes these sugars, because they are indigestible, journey intact to the colon, where their structure mimics molecules on the surface of gut epithelial cells.

Not exact matches

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

Esrp1 and Esrp2 are active specifically in epithelial cells, which form the skin, the inner layers of the gut and lung, and other tissues in the body.

People infected with HIV have few signs of microbial translocation during the first six months of infection as it takes time for the virus to kill off epithelial cells and weaken the gut wall so that bacteria can leak through — so treating them early could be more effective.

She and her group had studied the nature and function of epithelial cells, the gut - lining cells that come into contact with breast milk in nursing infants.

This is the first report of Paneth cell sensing of SIV infection and IL - 1β production that links to gut epithelial damage during early viral invasion.

The team's findings may also be relevant to inflammatory disorders that affect other parts of the body, such as the linings of the gut and bowel, which, like the skin, are replenished by epithelial stem cells.

Gut microbiota that live in the outer regions of the mucus and remain a safe distance from epithelial cells provide a benefit to the host, but Chassaing and Gewirtz hypothesize that microbiota that encroach upon host cells drive chronic inflammation that interferes with the normal action of insulin, promoting type 2 diabetes.

AIM2 is present in all immune and epithelial cells, which make up a large part of the intestine's cell population and help to maintain a healthy gut.

Studies have found a high - fat diet destroys gut microbiota, reduces the production of epithelial cells lining the intestine and causes gut bacteria to invade intestinal epithelial cells.

Scientists taking a close look at how a dangerous food - borne bacterium invades the gut have identified a new culprit, a molecule that normally helps hold the intestinal lining and other sheets of epithelial cells together.

The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens.

Butyrate is an important source of energy for the colonic epithelial cells, and according to some recent findings it promotes gut health.

Possibly, most effects of lectins are due to gastrointestinal distress through interaction of the lectins with the gut epithelial cells.

The gut is lined with epithelial cells that are covered by a layer of mucus and a wide array of microbes.

Resistant starch has been investigated in the past for its effects on bowel health (pH, epithelial thickness, and apoptosis of colorectal cancer cells); reduction in postprandial glycemia; increased insulin sensitivity; and effects on the gut microbiome.

However, whole foods like fruit and nuts are a very complex mixture of compounds, many having a beneficial effect by modulating gut microbiota or directly inhibiting inflammation in gut epithelial cells.