Sentences with phrase «of hemophilia»

Hemophilia A: a blood clotting disorder due to deficiency of coagulation factor VIII (this is the most common type of hemophilia in dogs).

Doctors treat either form of hemophilia with intravenous transfusions of proteins to replace the missing clotting factor.

We entered into an agreement with Bayer to research, develop and commercialize AAV gene therapy products for treatment of hemophilia A.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

In November, Denner helped facilitate the sale of hemophilia drug maker Bioverativ, for $ 11.6 billion, to Sanofi, a little more than a year after the company was spun out of Biogen, of which Denner is a director.

They're going through crates of the hemophilia drug Factor VII, yet to be approved for trauma but a wonder drug in stopping bleed - outs.

The Yanks have their deadline dandy Sonny Gray on the bump, while Cleveland counters with Trevor Bauer, who hopes to stave off his acute bouts of hemophilia.

Importantly, this stronger therapeutic effect did not trigger a higher level of unwanted immune reactions, a common complication of hemophilia A therapy.

«Because this variant provides more efficient bleeding control than currently available replacement drugs, while avoiding immune reactions, this could address the unmet needs of hemophilia A patients worldwide.

Imagine if genetic diseases could be removed from the very biological code of our species — a future in which the likes of hemophilia, cystic fibrosis or dozens of other afflictions are simply edited out of human embryos.

She added, «These patients have a severe or moderate level of hemophilia, with baseline clotting factor level less than or equal to 2 percent of levels in healthy people.

Sufferers of hemophilia live in a perpetual state of stress and anxiety: their joints wear down prematurely and they have bleeding episodes that feel like they will never end.

«This is the most significant advancement I have seen during my 20 years working in the field of hemophilia,» said Young, who is also a professor of Pediatrics at the Keck School of Medicine of USC and treats the most pediatric patients with hemophilia in California.

Sounds like science fiction, but new research in an animal model of hemophilia suggests that it can work - and now HD researchers are on the case.

Now, scientists at the Salk Institute are reporting the successful treatment of hemophilia B in mice using mRNA to deliver instructions for the clotting protein that is defective in the debilitating bleeding disorder.

Summary: British doctors say they have achieved «mind - blowing» results using gene therapy to rid people of hemophilia A.

Since completing the sale of our hemophilia program for $ 7 million in mid-December, Avigen's stock has appreciated 50 % and we believe that the Board's current strategy will continue to add value through an open and competitive process to evaluate potential merger transactions and a commitment to bring the strongest deal, if any, to stockholders for a vote.

Tests such as an APTT, or activated partial thromboplastin time, can detect a clotting disorder, but can not diagnose the particular type of hemophilia present.

Recovery for puppies who show signs of hemophilia can be poor, as many experience internal bleeding early on that can be lethal.

The scientists report that, in contrast to its action in hemophilia B, the other common form of hemophilia — in which furin improves blood clotting — furin exerts the opposite effect in hemophilia A, where it impairs clotting.

Dr. Jean Dodd, a noted blood specialist, has seen some notable connection between pano and von Willebrand's Disease (vWD), a different type of hemophilia.

The correct answer matters because RNAi is being studied as a potential basis for new kinds of drugs for the treatment of hemophilia, beta - thalassemia and many viral infections, says Dr. tenOever.

The finding offers potential for developing both gene therapy and more effective protein replacement treatments for hemophilia A, the most common form of hemophilia.

To verify that the process worked, the endothelial cells with the inversion - corrected genes were transplanted into F8 deficient mice (mice with hemophilia A) and the mice started producing the F8 clotting factor on their own, which essentially cured them of hemophilia A.

«Disruptive technology for the treatment of hemophilia: New therapy decreases incidence of bleeding by nearly 90 percent.»

This disease is a form of hemophilia, where the blood does not clot because it doesn't contain enough plasma protein.

They can develop thrombopathia, which is another type of hemophilia that often affects other Spitz breeds.

Health Issues: Hip Dysplasia can be found in the English Cocker Spaniel as can Von Willebrand's Disease, a form of hemophilia.

Measuring a different blood protein or the activity of Factor VIII can help to determine the type of hemophilia your dog may have.

Irish Wolfhounds are prone to cardiomyopathy, bone cancer, and Von Willebrand's disease (a type of hemophilia, or bleeding disease).

A particularly severe form of von Willebrand's blood - clotting disease occurs in German Wirehairs, as well as a milder form of hemophilia.

Some Dobermans have von Willebrand's Disease, a form of hemophilia.

Generally, a hematologist treats patients with blood disorders, such as types of hemophilia, leukemia, lymphoma, and sickle cell anemia.

Few will actually realize that when applying for an ordinary whole life or term life insurance policy, the insurance underwriters are going to be very interested in the type of hemophilia that they have and will often underwrite their applications quite differently based on this information.