Sentences with phrase «of host resistance»

These cases and our data raise the prospect that a variety of disease mitigation technologies have the potential to drive virulence evolution, including disease - ameliorating drugs [7,47] or genetic enhancements of host resistance [48].

Pre-print: Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses — William H Palmer — bioRxiv

Not exact matches

Antimicrobial resistance is driven by a host of factors.

However the CPP boosters will encounter stiff resistance from the meeting's host, Alberta finance minister Ted Morton, as well as a number of prominent pension experts.

The hope is that the developmental trend will continue down the path that is reflective of the principles of the coins they are hosting; by emphasizing censorship resistance and decentralization.

The advent of rice varieties bearing genes with resistance to the disease has changed the perception about the disease: the incorporation of host - plant resistance genes in rice varieties, their adoption and deployment in the world's main rice - producing environments is probably one of the most significant evidences of the role of plant pathology in agricultural development.

Host plant resistance: Natural defenses plants evolved to reduce the impact of herbivores.

Seemingly less dramatic than joining a resistance movement is joining the workforce, yet the attitudes of women in the workforce, and the risks they face as refugees in a host country, are often overlooked.

The demonstration is being organized by a group calling itself the Ghana First Patriotic Front (GFPF), who have chastised the government for accepting the deal, and the majority in Parliament for ratifying it despite strong resistance by the minority and a host of Ghanaians.

In an early sign that Sinai's plan may not encounter the kind of resistance that plagued St. Vincent's, fewer than two dozen people showed up last Thursday to an informational meeting hosted by Community Boards 3 and 6.

As some residents of one local community step up their resistance to a regional casino, people a few Thruway exits west are crossing their fingers that they could host a casino resort.

East 161st and 3rd Ave in front of the old courthouse 12:00 PM Assemblyman Michael Blake hosts Resistance Summer Day of Action in the Manhattan.

«My popularity in the black community, when I became governor, was 91 percent and by the beginning of 2009 my popularity in the black community had dropped to 54 percent because there has been a resistance to marriage equality such as there might be right here,» Mr. Paterson, a Democrat, said at a forum hosted by JP Updates, a Jewish news website.

Bacteriophages, or viruses that infect bacterial pathogens, may also act as vectors of virulence or of antibiotic resistance genes, ultimately making bacterial disease worse for the host.

The desire of the host to acquire antibiotic resistance genes from its guest could have driven this chain of events, he says.

«Increasing our understanding of how specific environmental factors affect the host and the pathogen as well as their interactions can inform strategies for developing robust crop resistance,» she said.

Toward that goal, Sandia National Laboratories is testing strains of algae for resistance to a host of predators and diseases, and learning to detect when an algae pond is about to crash.

«Adding realistic complexity such as population variation in resistance to our studies of toxicology is important to understanding how pesticides affect the interaction between host and their parasites.»

The windblown spores of Puccinia can travel great distances and quickly adapt to host plant resistance.

Prof. Raymond Kaempfer, the Dr. Philip M. Marcus Professor of Molecular Biology and Cancer Research at the Institute for Medical Research Israel - Canada (IMRIC), in the Hebrew University's Faculty of Medicine, explains: «Rather than targeting the bacterial pathogens, which can then mutate to develop antibiotic resistance, host - oriented therapeutics have the advantage of remaining effective even against infections with antibiotic - resistant strains.

Because this approach jams the host cell machinery rather than directly attacking the bacteria, the chances of bacteria developing resistance could be very low, say the researchers.

Beyond their participation in host defense, increasing evidence suggests that these modifications also play important roles in the regulation of gene expression, virulence and antibiotic resistance.

Globalisation has resulted in the movement of humans and animals all across the world, bringing pathogens into contact with hosts that haven't had the opportunity to establish resistance.

Iran may be among the world's most heavily censored nations, but it is also host to one of the Middle East's most vibrant online communities, and previous attempts to restrict access have met with widespread resistance.

Greenbaum believes it might be more difficult for malaria to evolve resistance to a drug aimed at a protein in its host rather than at one of its own.

A unique selling point is their host specificity, meaning little or no collateral damage to neighbouring («good») bacteria, and they do not drive the development of resistance in non-target bacterial species.

Looking for drugs that target interactions between a virus and host, such as these proteins involved in budding, reduces the likelihood that a virus would mutate to develop resistance, which is an advantage of this strategy, Harty said.

The strategy would take advantage of parasite refugia — host populations that have not been treated with drugs, thereby serving as «safe zones» where parasites don't develop drug resistance.

Hospitals and clinics are the perfect breeding ground for drug - resistant bacteria — plenty of close contact among sick and vulnerable hosts, plus extensive antibiotic use that forces bacteria to develop resistance.

Also, phages evolve with the host and have the potential to overcome bacterial resistance, said coauthor Jochen Klumpp of the Institute of Food, Nutrition and Health, ETH Zurich.

Still, the apparent benefits of resistance may not be big enough to help the gene spread through a population in the wild, where not all the hosts are infected, says co-author Jason Rasgon.

«Importantly, fighting a pathogen by hitting an enzyme from the host cell is likely to slow the emergence of drug resistance, because the pathogen can not easily escape through the selection of target mutations,» Professor Doerig said.

Associate Member, Departments of Pathology, Experimental Medicine, Oncology, Center for Host Resistance and Goodman Cancer Center, McGill University

The Prevention and Therapy session will tackle research on host - pathogen interactions, and the genetic determinants of infectious disease, innate immunity, antimicrobial resistance and vaccine development.

The meeting explored the genomic epidemiology of the host, vector and parasite, highlighting the practical relevance of this research to global health, including antimalarial drug resistance, insecticide resistance, vaccine design, and mechanisms of protective immunity.

The JCVI GCID aims to study pathogens and the genetic determinants of their virulence, drug - resistance, immune evasion and interactions with the host, and host microbiome to advance research in pathogenicity, drug - resistance, disease transmission and vaccine development.

The awards span the broad mission of the NIH and include groundbreaking research, such as engineering immune cells producing drugs at the site of diseased tissue; developing a sensor to rapidly detect antibiotic resistance of a bacterial infection; understanding how certain parasites evade host detection by continually changing their surface proteins; and developing implants that run off the electricity generated from the motion of a beating the heart.

Increased host resistance against Pneumocystis carinii pneumonia in γ $ ẹlta $ T - cell - deficient mice: protective role of gamma interferon and CD8 + T cells.

Scientists do not know if the emergence of disease outbreaks is due to the introduction of novel pathogens or due to changes in existing pathogens that may be caused by deteriorating environmental impacts and / or reduced host resistance.

Preliminary resistance trials are being conducted on different varieties of Ohi'a trees, and scientists are looking at the genetics of both the pathogen and host for potential long - term strategies.

Topics this year include genomic epidemiology of the host, vector and parasite, highlighting the practical relevance of this research to global health, including anti-malarial drug resistance, insecticide resistance, vaccine design, and mechanisms of protective immunity.

The impact of host longevity on disease transmission: host - pathogen dynamics and the evolution of resistance.

The focus is on molecular microbiology and virology, and includes topics such as genomics, the gamut of plant and animal host - pathogen interactions, host immune responses, characterization and evolution of virulence determinants, cell cycle and differentiation, symbiosis in plant and animal associations, environmental microbiology, biodiversity and evolution, population dynamics, sex and mutagenesis, antibiotic resistance and production, drug and vaccine targets, as well as aspects of prion diseases and of fungal and protozoan biology.

Britt Koskella, Daniela Vergara & Curtis M. Lively — 2011 (3)([email protected]) Keywords: cost of resistance, host — parasite co-evolution, local adaptation, Red Queen hypothesis, specificity of resistance

Host resistance to the chytrid fungus of amphibians Amphibians in Panama have experienced declines for over a decade due to the disease chytridiomycosis, caused by the fungal pathogen Batrachochytrium... AmphibiaWeb

Ulla Carlsson - Granér & Peter H. Thrall — 2006 (4)([email protected]) Keywords: disease dynamics, disease transmission, evolution of resistance, host longevity, Microbotryum violaceum, spatial structure, sterilizing pathogen

It might be in the hosts» best interest, after all, to resist being manipulated by the microbes: Such resistance would mean hosts could keep more resources for themselves, increasing their odds of survival.

The role of gene regulation in C. auris drug resistance mechanisms and host interactions — such as overexpression of ERG11 and other known fluconazole resistance genes — are currently unknown.

The Department of Translational Research hosts 5 technological platforms (Genomics, Protein arrays, High - content screening, Experimental radiotherapy and Preclinical investigation), 4 labeled teams (resistance to therapy in breast cancers, translational pediatrics, angiogenesis, and immunotherapy) and 3 emergent teams (Circulating biomarkers, uveal melanoma, and new targets in triple negative breast cancers).

Of the various strategies tried, enhancing host - plant resistance is considered one of the important approaches to tackle this diseasOf the various strategies tried, enhancing host - plant resistance is considered one of the important approaches to tackle this diseasof the important approaches to tackle this disease.