Sentences with phrase «of human airways»

A research team from the University of Minnesota and the Mayo Clinic took cells from the lining (epithelium) of human airways and exposed them to Alternaria.

Not exact matches

By printing multiple lung airways — or any other afflicted organ — from a human patient and testing drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to human clinical trials with greater confidence the drugs will actually work, according to Wadsworth.

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

The unaltered hemagglutinin is akin to a key that unlocks a so - called receptor molecule in cells lining the upper airways of humans and other mammals.

Now, scientists from the Perelman School of Medicine at the University of Pennsylvania reveal that the release of AMPs is partially controlled by bitter taste receptors in the upper airway on a cell previously identified in animals and only recently in humans known as solitary chemosensory cells (SCCs).

«In our human airway epithelial model system, one of the drugs destabilizes and deactivates the protein that the other drug tries to correct,» said Martina Gentzsch, PhD, an assistant professor of cell biology and physiology and senior author of the UNC Science Translational Medicine paper.

But working with human smooth muscle cells isolated and grown from the healthy parts of airway tissue surrounding excised tumors, Benjamin Kalbe and his colleagues applied a large number of odor molecules and watched two of them activate the muscle cells.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

When Liesman infected human airway cells in the lab with this re-engineered virus, she saw infected cells ball up and puff out of the airway epithelium.

Called the olfactory recess, it's a large maze of highly convoluted airways that humans and all other primates lack.

Their test includes three types of human cells that are typically in a person's airway.

If this type of therapy proves safe in humans, a syringe full of oxygen microbubbles could help avert brain damage and death for the victims of cardiac arrest, asthma attacks, strokes, and injuries to the lungs, airway, or face.

Asthma is a disease of the human respiratory system in which the airways narrow, often in response to a «trigger» such as exposure to an allergen, cold air, exercise, or emotional stress.

Clean energy policies decrease not only carbon pollution linked to climate change but also other types of pollution that harm human health, such as sulfur oxides, nitrogen oxides, and fine particles that can damage the airways of humans and other organisms.

Human flu strains can infect both kinds of cells, but avian flu strains can bind to and infect only the ciliated kind, which are similar to cells in the airway and the gut of birds.

According to Earl Brown, professor of medicine at the University of Ottawa, the more limited ability of the avian flu virus to infect cells in the human airway thus also appears to be associated with infection of the deep areas of the lung where oxygen and carbon dioxide are exchanged.

A number of bacterial and viral infections can gain a foothold in the human body through adsorption via the intestines and airways, such as Salmonella and the flu.

The research team then tested RMC - 1 in cultured human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).

Ripping a page from the Star Trek script, specialized cells of the barrier that lines the inside of the intestines and airways of humans have invoked a biological version of Captain Kirk's famous command «shields up» as a first defense against invading microbes.

The human airway is lined with two kinds of epithelial cells — those that possess hairlike fringes called cilia and those that don't.

«This is a whole new way of looking at immune surveillance in the epithelium of the human gut and airway,» said Lo, a distinguished professor in the medical school's Division of Biomedical Sciences.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

Hypertonic Saline Primes Activation of the p53 — p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines.

The public disclosure of this expanded collaboration coincides with the publication in the peer reviewed journal Nature Methods of data showing new capabilities of the Lung - Chip technology to achieve accurate modeling of the human lung small airways.

This micro-engineered Airway Lung - Chip recapitulates key features of viral - induced human asthma exacerbation and provides unique opportunities to explore the complex mechanisms underlying asthma exacerbation in a human - relevant model.

Monell researcher and University of Pennsylvania medical student Jennifer Douglas will discuss new frontiers in taste biology, with a focus on taste receptors located throughout the human body (including the stomach, intestines, pancreas, testes, and airways).

The bill, expected to come up for a vote in the Senate after Thanksgiving, also would require the U.S. Centers for Disease Control and Prevention to conduct a five - year study on the human health effects of per - and polyfluoroalkyl substances — classes that include the compounds in Airway Heights» groundwater.

Enhanced Expression of Myristoylated Alanine — Rich C Kinase Substrate (MARCKS) in Airway Epithelium of an Animal Model of Allergic Airway Inflammation and Human Patients with COPD

Additionally, we clarified the role of iNKT cells in human asthma by carefully enumerating cell numbers in airway samples from asthma and COPD patients.

Once produced, NO is freely diffusible and enters target cells and into the airway and can be detected in exhaled breath of all humans.

They heightened the efficacy of the antimicrobials secreted by human airway cells, the body's natural immune response, as well.

IMAGE: Human airways already demonstrate gender - based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in...

WASHINGTON - Human airways already demonstrate gender - based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

A multi-institution research team that includes Children's National Health System attempted to characterize gender - based epigenomic signatures in the human airway early in children's lives with a special attention to defining DNA methylation patterns of the X chromosome.

The treatment can lead to an all natural and noninvasive remodeling of the bony and soft tissues surrounding the human airway, offering patients the prospect of a lifetime of optimal air flow and airway capacity and restorative sleep.

Dogs snore for the same reasons humans do — a blockage of the airways during sleep.

The effects of smoke on horses are similar to effects on humans: irritation of the eyes and respiratory tract, aggravation of conditions like heaves (recurrent airway obstruction), and reduced lung function.

This is because aerobic bacteria recovered from the airways of healthy cats, dogs, and humans, does not exceed 5 X 103 organisms / ml.

For example, in humans we know that while actual symptoms of asthma occur in episodes, the airways of the lung are diseased all the time.

Feline asthma is similar to human asthma, in that it is a chronic inflammation of the airways inside the lungs.