Sentences with phrase «of human breast carcinomas»

Trastuzumab is a humanized monoclonal antibody that targets the HER2 receptor, which is overexpressed in approximately 20 — 30 % of human breast carcinomas [11].

Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs.

Each circle represents an individual sample of human breast carcinoma (n = 392 for TCGA dataset; n = 261 for Bittner dataset).

Not exact matches

Dr. Jos Jonkers» research group studies the genetic basis of human breast cancer, using advanced mouse models for p53 - induced breast cancer, BRCA1 - and BRCA2 - associated hereditary breast cancer, and E-cadherin mutated invasive lobular carcinoma.

Research Paper Immunohistochemical Expression of Cyclin D1 in Invasive Ductal Carcinoma of Human Breast Mahmoud Assem, Eman Ahmed Youssef, Radwa Mohammed Rashad, Mona Abdel - Hamed Yahia Oncomedicine 2017; 2: 80 - 87.

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Here we report that HB1.F3 NSCs can be engineered to express and secrete functional full - length HER2 - specific human immunoglobulin molecules that can selectively bind to and inhibit the proliferation of HER2 - positive breast carcinoma cells.

Studies of Gluts in human tumors have shown a significant increase in the abundance of Glut1 and Glut3 mRNA in cancers of the esophagus, colon, and pancreas, overexpression of Glut1 and Glut3 mRNA and Glut1 protein expression in head and neck tumors and Glut1 protein overexpression in breast and renal cell carcinomas

The curcumin metabolite tetrahydrocurcumin decreases the activity of the phase III transporters in human cervical carcinoma and breast cancer cell lines.