Sentences with phrase «of human cancers express»

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Next, the researchers tested the effects of RK - 33 and radiation in mice that had been injected with human prostate cancer cells that highly express DDX3.

Over the past two years, investigators from the Perelman School of Medicine at the University of Pennsylvania have reported results from a human trial in GBM using chimeric antigen receptor (CAR) T cell therapy, through which patients» own T cells were engineered to track down and kill cancer cells that express a tumor - specific protein known as EGFRvIII.

A team led by Jos Jonkers at the Netherlands Cancer Institute discovered that a mouse harboring an analog of the cancer - associated human BRCA1 mutation, BRCA1184delAG, expresses a BRCA1 protein that is missing a structural component called a RING dCancer Institute discovered that a mouse harboring an analog of the cancer - associated human BRCA1 mutation, BRCA1184delAG, expresses a BRCA1 protein that is missing a structural component called a RING dcancer - associated human BRCA1 mutation, BRCA1184delAG, expresses a BRCA1 protein that is missing a structural component called a RING domain.

As recent data suggest, PSMA is an important cancer antigen expressed on many human prostate, bladder, renal as well as ovarian cancers, so additional study of the possible benefits of this therapy are important.»

Human colorectal cancer samples express low levels of MCRS1 low (left) and high levels of MCRS1 (right).

The goal of the first experiment was to see whether lncRNAs are differentially expressed in prostate cancer by measuring total RNA from prostate cancer cell lines and normal epithelial prostatic cells using NCode human ncRNA array and SurePrint G3 human lncRNA microarrays.

Furthermore, many PMA - stimulated secreted proteins are expressed in a range of human cancers — an interesting finding, considering the HMEC line used for the studies is incapable of producing tumors.

Being both tumor - specific and widely expressed in human tumors, MAGE - A3 is an ideal cancer vaccine target and will be the focus of many clinical trials, including the largest clinical trial ever conducted in lung cancer, MAGRIT, launched by GlaxoSmithKline in 2007.

Identification of proangiogenic TIE2 - expressing monocytes (TEMs) in human peripheral blood and cancer.

Review of «Antitumor Effects of CD40 Ligand - Expressing Endothelial Progenitor Cells Derived From Human Induced Pluripotent Stem Cells in a Metastatic Breast Cancer Model» from Stem Cells TM by Stuart P. Atkinson.

Berkeley Lab researchers have developed the first clinically - relevant mouse model of human breast cancer to successfully express functional estrogen receptor positive adenocarcinomas.

ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are exprehuman autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expreHuman METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expressed.

Here, we tested whether human gastric cancers, which are among the most aggressive tumor entities, express the cellular receptor of Shiga toxin, the glycosphingolipid globotriaosylceramide (Gb3 / CD77).

Triple negative breast cancer is a type of breast cancer that does not express receptors for the hormones estrogen and progesterone, or for human epidermal growth factor.

Studies show that human cancer cells express high levels of the fatty acid synthase enzyme, which is associated with aggressive tumor behavior and tumor - cell growth.