Sentences with phrase «of human cartilage»

Scalpel in hand, Zhao sat at a table carving precise measurements out of realistic material designed to mimic the texture of human cartilage.

Not exact matches

Working with Skeletal Biologists at Southampton General Hospital, Catarina is investigating new optical techniques to monitor the development of the cells, used in new regenerative medicine approaches — in this case, to create and grow cartilage from human stem cells.

Researchers report in the Journal of Biomedical Materials Research Part A that they successfully grew cartilage around carbon nanotubes in their lab — and are optimistic that one day they will be able to duplicate the feat inside the human body.

They exposed human and bovine cartilage cells to varying doses of lithium chloride over a 24 hour period and recorded the length of the primary cilia and the activation of Hedgehog Signalling.

Human chondrosarcoma HCS - 2 / 8 cells, which are a type of benign bone cancer cells, can be used to investigate how optimization of culture conditions could improve the synthesis of cartilage - specific molecules.»

Researchers from the University's Institute of Ageing and Chronic Disease, led by Senior Lecturer in Orthopaedic Sciences Dr Simon Tew, examined molecular messages produced by cartilage cells in both humans and rats.

Extending their work to independent data, not used to originally identify the networks, Dr Tew and colleagues demonstrated a signature of disease - associated messages that could distinguish between osteoarthritic and healthy cartilage in humans.

Using a method that creates networks from these messages it was possible to identify «blocks» of messages with similar functions that were strongly associated with diseased cartilage; notably these same blocks of messages were found for diseased cartilage from both rats and humans.

• News from the World of Adult - Stem Cell Research • At the University of California at Los Angeles, Marc Hedrick's team used human adult fat cells extracted during liposuction to make cells resembling cartilage, bone, and muscle.

Even more encouraging, the engineered tissues still continued to produce human neural, cartilage, and liver cell proteins, the team reports online this week in the Proceedings of the National Academy of Sciences.

They practiced carving on a 3 - D printed model of a harvested human cartilage graft created through a CT scan of a pediatric patient's rib.

One of his project areas involves cartilage in the human knee, elucidating the series of events that lead to osteoarthritis.

When the team examined 40 other mice with RASF / cartilage implants, it found human RASFs in the blood of about half, strongly suggesting that the RASFs use the bloodstream to invade the rest of the body.

The study is the first, say its authors, to provide evidence that adenosine, a biochemical at the heart of human cellular function, plays another crucial role — keeping on hand a steady number of healthy chondrocytes, the cells that make and sustain cartilage.

Stem cells from human ears have successfully been grown into chunks of cartilage that could replace the synthetic materials currently used in surgery.

Preclinical studies in mice and human cells suggested that the removal of SnCs significantly reduced the development of post-traumatic OA and related pain and created a prochondrogenic environment for new cartilage to grow and repair joints.

Downregulation of microRNA - 448 inhibits IL - 1ß - induced cartilage degradation in human chondrocytes via upregulation of matrilin - 3.

Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage.

Histopathology in Tg197 mice is characterized by infiltration of inflammatory cells, synovial hyperplasia, articular cartilage destruction and bone erosion symptoms, closely resembling those of human rheumatoid arthritis.

In addition, one of the genes identified — an ortholog of human COL2A1 is commonly used as a chondrocytic maker in the development of cartilage (Zaucke et al., 2001).

On the other hand, there are many other tissues — notably, the kidney and articular cartilage — where p16Ink4a - expressing senescent cells appear to be a contributing factor to human and murine degenerative aging, but which were not evaluated in treated or control mice in this study, and it would be of interest to see the effects of ablation of p16Ink4a - positive senescent cells.

Cambridge, Mass. - September 5, 2012 - A team of experts in mechanics, materials science, and tissue engineering at Harvard have created an extremely stretchy and tough gel that may pave the way to replacing damaged cartilage in human joints.

Human embryonic stem cells can turn into a variety of different cell types, including (A) gut, (B) neural cells, (C) bone marrow cells, (D) cartilage, (E) muscle, and (F) kidney cells.

Human embryonic stem cells grown at the University of Wisconsin - Madison randomly changed into cell types found in the A) gut B) brain C) bone marrow D) cartilage E) muscle F) kidney Scientists haven't learned to control the development.

Prof. Dr. Ivan Martin's research group at the Department of Biomedicine has now been able to demonstrate that by forcing certain molecular events occurring during the embryonic development of articular cartilage it is possible to generate stable cartilage tissue from adult human mesenchymal stem cells.

Review of «Footprint free human iPSCs from articular cartilage with redifferentiation capacity - a first step towards a clinical grade cell source» from Stem Cell Translational Medicine by Stuart P. Atkinson

It was discovered the amount of enzymes which damage cartilage is limited when a compound known as diallyl disulphide is introduced to a laboratory human cartilage cell - line.

The human body is made up of 60 percent Type II collagen, and Hydrolyzed Type II collagen contains the amino acids found in human cartilage.

To understand why these nutrients might be so critical to joint health, I consulted several textbooks and learned that hyaline cartilage, the most common type in the human body, derives its strength from a dense, criss - crossing, ropey network of collagenous fibers, and its resilience from the gel - like matrix into which these fibers are embedded.

Collagen is the protein produced by the human body that helps and repairs soft tissues of the body like muscles and cartilages.

Chondroitin is a component of human connective tissues found in cartilage and bone.

Glucosamine and chondroitin are natural chemicals found in the cartilage of both dogs and humans, including the cartilage in joints.

Glucosamine and chondroitin sulfate have been shown to help alleviate chronic pain associated with osteoarthritis in humans, 14 and high levels of n - 3 polyunsaturated fatty acids have been shown to reduce inflammation and decrease cartilage degeneration.15 Both are commercially available in «feline joint» supplements.

DJD, also called osteoarthritis, causes a progressive loss of cartilage and the death of cells that produce cartilage in both humans and dogs.

Gimmicky additions to pet foods include marigold and chicory extract, and touting chicken byproduct meal as a «source of chondriotin and glucosamine» in reality means that much of this ingredient is probably of low protein value because it contains a lot of cartilage and bone from the remains of ground up chicken parts not considered fit for human consumption.

Glucosamine is a natural compound found in healthy human and animal cartilage that helps to protect and repair joints by increasing the production of molecules that form and repair cartilage.

Research done by the Comparative Orthopaedics Laboratory allowed the continued application of cartilage cell transplantation to the human knee; by early 2004 over 10,000 cartilage cell transplantation procedures had been performed in the United States using techniques validated by the laboratory.

Research done by the Comparative Orthopaedics Laboratory allowed the continued application of cartilage cell transplantation to the human knee.