Sentences with phrase «of human central nervous system»

The technique makes it possible to study motor neurons of the human central nervous system in the lab.

In his Ph.D. project, Dr. Henri Leinonen investigated functional abnormalities of the retina using mouse models of human central nervous system diseases.

Here Jacques Monod (1971) would appear to agree with Popper in that he calls the problem of the human central nervous system «the second frontier,» comparing its difficulty with the «first frontier,» the problem of the origin of life itself.

Not exact matches

When it comes to medical treatment, the brain and central nervous system remain the darkest, most forbidding frontiers in the human body — and yet our knowledge of how the brain and mind actually work seems to be growing by leaps each year.

It needs to be stated first that human beings are highly complex psycho - physical organisms with literally thousands of energy events interacting with each other and with and under the dominance of an «organizing center of experience» (the brain), also present in animals with central nervous systems.

A single human egg cell is alive, but it has no experiences like those of an adult, or a child, or even of an animal with a central nervous system.

Since Hartshorne begins with human experience, the first cosmological question that arises for him does not have to do with atoms and molecules but with the relation of human experience to the body, especially to the central nervous system and the brain.

In other words, it looks like there's something in the human central nervous system that an educated chili head might call an Endo - Capsaicin Receptor system (a system designed to sense and process capsaicin that, when activated, can have significant effects on the central nervous system at large) and that when this system is frequently activated by the digestion of capsaicin, we see all kinds of health benefits.

Specifically, when capsaicin frequently binds to receptors within the human central nervous system's TRPV1 channel (the sensory receptor system for pain and heat detection), these receptors deplete and this depletion results in a whole host of benefits for the central nervous system at large, including terminating cancer cells, increasing the metabolic rate and digestive efficiency, increasing circulatory blood flow, and combatting inflammation, and making you feel better about the world.

Neonicotinoids gained popularity as pesticides in the 1990s in part because they target the central nervous system of crop - destroying insects, but don't have the same effects in humans.

One concern raised by the human brain organoid implants «is that functional integration [of the organoids] into the central nervous system of animals can in principle alter an animal's behavior or needs,» said bioethicist Jonathan Kimmelman of McGill University in Montreal.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

The device, part of the Lab's iCHIP (in - vitro Chip - Based Human Investigational Platform) project, simulates the central nervous system by recording neural activity from multiple brain cell types deposited and grown onto microelectrode arrays.

Specifically, stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (brain and spinal cord) neurons as well as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature and itch perception.

The human brain is the center of the central nervous system in humans as well as the primary control center for the peripheral nervous system.

This species has been shown to demonstrate a progression of Lyme disease most similar to humans, particularly related to erythema migrans, carditis, arthritis, and neuropathy of the peripheral and central nervous systems.

The inhibition of MMP - 3 may be a promising therapeutic target for human central nervous system disease, including SCI,» notes Dr. Yune.

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, has been discovered by researchers.

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

Ultimately, the enhanced understanding of central nervous system organization that has derived from the research of these three scientists may lead to new and more effective ways to repair diseased or damaged circuits embedded in the human brain and spinal cord.

Myelomeningocele: characterization of a surgically induced sheep model and its central nervous system similarities and differences to the human disease.

When T. gondii infects an intermediate host such as rodents or humans, it infiltrates the central nervous system and forms slow - growing cysts inside neurons where it can persist for the life of the host [4].

Most recently, Dr. Gringeri was the Chief Operating Officer for Amsterdam Molecular Therapeutics (AMT), a Netherlands - based company engaged in human gene therapies for orphan diseases related to metabolic disorders, liver diseases, blood diseases, and disorders of the central and peripheral nervous systems.

The embryonic Drosophila central nervous system similar to the human spinal cord is a paradigm for understanding the cellular processes and genetic pathways regulating the formation and maintenance of a diverse population of nerve cells.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

The significant difference in outcome achieved by transplantation of hGDAsBMP versus hGDAsCNTF demonstrates clearly that not all astrocytes are equivalent in respect to their therapeutic value, and this appears to be the first study demonstrating functional differences between different human astrocyte populations with respect to repairing the adult central nervous system.

The «heart - on - a-chip,» which builds off previous successful iCHIP research on the peripheral and central nervous systems, involves the use of human cardiac cells cultured for up to nine days on the engineered chip.

Characteristics of human disease such as erythema migrans, carditis, arthritis, and neuropathy of the peripheral and central nervous systems have all been observed in macaques [28].

Thus, the lab's approach may hold great promise for potential treatment of (neuro) inflammation - related human diseases both in and outside the central nervous system.

In brief our present studies provide the first demonstration of the utility of human astrocyte transplantation as a therapy for central nervous system injuries.

Recent studies of various mouse strains showing «striking differences» in the repair of axons — the long, slender projections in nerve cells that conduct electrical impulses — could be applied to human cells «to identify biomarkers of central nervous system repair potential and provide new targets for intervention,» he says.

In addition, our studies provide a specific population of human astrocytes that appears to be particularly suitable for further development towards clinical application in treating the traumatically injured or diseased human central nervous system.

We have focused on the less - studied replacement of astrocytes, the major support cell in the central nervous system, by generating astrocytes from embryonic human glial precursor cells using two different astrocyte differentiation inducing factors.

December 21, 2015 — Noteworthy NIH advances in basic research include charting human genetic variation across the globe, the discovery of lymphatic vessels in the central nervous system, and insights into energy - burning fat cells.

Eight HARs showed differences in their enhancer activity when the human mutations were present.4 These differences modify how genes were expressed in the developing limb (HAR2, 2xHAR114), eye (HAR25), and central nervous system (2xHAR142, 2xHAR238, 2xHAR164, 2xHAR170, ANC516 / HARE5).4, 10 Because relatively few time points have been examined, it is likely that an even higher percentage of the tested HARs are active enhancers at some point during embryonic development or in adult tissues, possibly with human - chimp differences.

In mouse models in which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 days3.

Rodent models can't capture the years long path of human brain development, but 3D human organoids now give researchers a window into later stages of development of our burgeoning central nervous system.

However, they say the work at least proves the potential for mRNA therapy to successfully treat not only hemophilia B but also other human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system, lung and eyes.

Food science: - Sulfer is one of the most abundant mineral elements in the human body - Sulfer is required for the synthesis of glutathione, one of our endogenous (we make our own) antioxidants — an antioxidant that neutralizes free radicals, helps control blood pressure and inflammation, and helps the liver process toxins - Sulfur is essential for Taurine synthesis — taurine is essential to our Central nervous system and the workings of our cardiovascular system - Sulfur helps bind the amino acid chains that form insulin.

Exposure to pesticides and fungicides have been proven to cause negative short - term or long - term effects on the environment and the health of animals and humans, especially in the reproductive, endocrine and central nervous systems.

CNS The human central nervous system consists of the brain and spinal cord.

The central nervous system along with the peripheral nervous system comprise a primary division of controls that command all physical activities of a human.

Docosahexaenoic acid (DHA) which is an omega - 3 fatty acid that is primary structural component of the human brain, cerebral cortex — DHA plays a key role in the healthy creation of the central nervous system.

Perhaps one of the most critical elements in a human's nervous system development is the Central Nervous nervous system development is the Central Nervous Ssystem development is the Central Nervous Nervous SystemSystem.

The rabies virus attacks the brain and central nervous system and is transmitted to humans through the bite of an infected animal.

This incurable viral disease affects the central nervous system of almost all mammals, including humans if infected.

These receptors are found throughout the central nervous systems of humans and non-human animals, and play an important role in pain pathways.

Rabies Protects against a fatal viral disease that affects the central nervous system of all mammals - including humans.

Rabies is a disease caused by a virus that can affect the central nervous system (brain and spinal cord) of any kind of mammal, including humans.

Review and comparison of neuromuscular and central nervous system marifestations of hyperthyroidism in cats and humans.