Like the Helsinki Declaration, which forever altered the ethical landscape
of human clinical research, the aim of the Basel Declaration is to bring the scientific community together to further advance the implementation of ethical principles such as the 3Rs whenever animals are being used and to call for more trust, transparency and communication on the sensitive topic of animals in research.
Not exact matches
The Albert and Mary Lasker Foundation announced yesterday that it was presenting its prestigious 2017 Lasker - DeBakey
Clinical Medical
Research Award to a pair
of National Cancer Institute researchers, Douglas Lowy and John Schiller, who created a vaccine to prevent
human papilloma virus, or HPV, from taking hold in the body.
The APA states despite the persistence
of stereotypes that portray lesbian, gay, and bisexual people as disturbed, several decades
of research and
clinical experience have led all mainstream medical and mental health organizations in this country to conclude that these orientations represent normal forms
of human experience.
Despite the persistence
of stereotypes that portray lesbian, gay, and bise xual people as disturbed, several decades
of research and
clinical experience have led all mainstream medical and mental health organizations in this country to conclude that these orientations represent normal forms
of human experience.
The company also works with cardiologists and other physicians to provide healthcare providers and their patients a better way to reduce the intake
of excessive dietary sugars which excellent
clinical research has now demonstrated to be a challenge to the
human body.
«Recent
research on
humans published in the American Journal
of Clinical Nutrition earlier this year indicates that drinking diet beverages does not cause people to overeat or to increase their intake
of sweet foods and beverages.
Additional
human clinical research suggests that Suntheanine may have application in diminishing normal symptoms
of premenstrual syndrome (PMS), improving learning performance, heightening mental acuity, promoting concentration, reducing negative side effects
of caffeine and supporting the immune system.
«Previous
research, including
human clinical trials, supports that diet beverages are an effective tool as part
of an overall weight management plan.
Immediate
research needs include additional
human clinical trials and investigations
of measures to improve the bioavailability
of curcumin.
Congratulations to Diane Lynn Spatz, PhD,
clinical coordinator
of Children's Hospital
of Pennsylvania's Mothers» Milk Bank, upon her recent appointment to the Task Force on
Research Specific to Pregnant Women and Lactating Women, which is coordinated by the National Institute
of Child Health and
Human Development at the National Institutes
of Health.
Meanwhile the general term «
human milk feeding» is used by researchers and administrators to describe both mother's own milk and donated milk (or combinations
of the two) despite the fundamental differences in the two, according to the lead author, Paula Meier, PhD, Rush University Medical Center's director for
Clinical Research and Lactation, Special Care Nursery and a Professor
of Pediatrics and Women, Children and Family Nursing.
Her primary focus was the conduct
of clinical research and the system
of human - subject protections, and the regulatory system for dietary supplements.
Dr Frances Flinter (Chair), Consultant in
Clinical Genetics, Guy's Hospital, London & Chair
of the
Human Genetics Commission working group to develop a common framework
of principles for direct genetic tests; Dr Richard Durbin, Co-Chair
of the 1000 Genomes Project, Wellcome Trust Sanger Institute, Hinxton; Dr Barbara Prainsack, Senior Lecturer Medicine, Science & Society, Kings College, London; Prof. Martin Richards, Emeritus Professor
of Family
Research, University
of Cambridge.
To succeed as a clinician - researcher, a physician - scientist uses his or her mastery
of both
clinical practice and basic science
research in parallel, often drawing on both skill sets to find advances in the diagnosis, treatment, and prevention
of human disease.
The biobank
of MedUni Vienna and Vienna General Hospital is a central service facility dedicated to the storage
of human tissue, cell material and body fluids for more in - depth diagnosis, academic
research projects and
clinical tests, as well as working - up samples by way
of a medical service.
As director
of the United Kingdom
Human Tissue Bank, Samantha Orr manages staff and takes part in
clinical and
research liaison activities.
The Office for
Human Research Protections (OHRP), an office within the Department of Health and Human Services (DHHS), develops policies to protect human subjects and monitors clinical trials at research institut
Human Research Protections (OHRP), an office within the Department of Health and Human Services (DHHS), develops policies to protect human subjects and monitors clinical trials at research insti
Research Protections (OHRP), an office within the Department
of Health and
Human Services (DHHS), develops policies to protect human subjects and monitors clinical trials at research institut
Human Services (DHHS), develops policies to protect
human subjects and monitors clinical trials at research institut
human subjects and monitors
clinical trials at
research insti
research institutions.
«They are developing the
clinical genomics necessary to foster and support the Precision Medicine Initiative
of the National Institutes
of Health, and generating the genomics data that further drives
human genome
research.»
For those with a
research background, it could mean learning
clinical study design and the bioethics
of human research.
«We have now found a potential mechanism, and at this point in our
research, we need to test
human participants in a blinded, placebo controlled
clinical study — the same technique we used to study the behavioral effects
of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.
Because the center is made up
of four diverse divisions (Public Health Sciences, Basic Sciences,
Clinical Research, and
Human Biology), the talks cover something outside a member's direct area
of expertise most
of the time, which makes for an eager and enthusiastic audience.
HBI member V. Wee Yong, PhD and
research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are comp
research associate Susobhan Sarkar, PhD, and their team including researchers from the Department
of Clinical Neurosciences and the university's Southern Alberta Cancer
Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are comp
Research Institute, looked at
human brain tumor samples and discovered that specialized immune cells in brain tumor patients are compromised.
ASMI researchers are involved in different fields such as biomechanics (motion analysis, which includes cadaver
research, namely, the use
of human limbs to analyze anatomy, motion, and the strength
of muscles, tendons, ligaments, and bones) and
clinical research (tracking patients to see how successful they are returning to sport after treatment with surgery or physical therapy).
In the newly reconstituted Scientific Responsibility,
Human Rights, and Law Program, the missions
of the CSFR and NCLS continue to complement one another as staff pursue projects such as continuing seminars for judges on neuroscience and the law, personalized medicine, the state and future
of clinical trials, advocacy in science, understanding responsible
research practices in changing
research environments, and joint AAAS - China Association
of Science and Technology workshops on science and ethics.
Aging
research may be on the rise, but it does have its own set
of unique limitations in terms
of how quickly discoveries in the lab turn into
human clinical trials.
The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell
Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical
Research Center; the use
of this facility is an important step in the process as preclinical
research moves toward human clinical
research moves toward
human clinical trials.
For example, Matt Krause, director
of human resources at CV Therapeutics, says, «Our
research programs include multiple, cutting - edge cardiovascular product candidates in various stages
of clinical trials and preclinical programs, all
of which rely heavily on the contributions from our many B.S. - and M.S. - level scientists.»
In February 2011 virologist Jay Lalezari
of Quest
Clinical Research reported the first use
of this technology in
humans.
«In over 100 years
of unrestricted
clinical research,
human fetal tissue has failed to provide a single medical treatment...»
My
clinical responsibilities now include part - time direction
of a hospital molecular genetics lab that specializes in the diagnosis
of human genetic diseases and hematologic malignancies — a return to my early
research interest in
human genetics.
Samuel Weiss, PhD, Professor and Director
of the HBI, and
Research Assistant Professor Artee Luchman, PhD, and colleagues, published their work today in
Clinical Cancer Research, which is leading researchers to start a human phase I / II clinical trial as early as Spri
Clinical Cancer
Research, which is leading researchers to start a
human phase I / II
clinical trial as early as Spri
clinical trial as early as Spring 2015.
medical and scientific educations place them at an ideal intellectual vantage point to facilitate the transfer
of clinical observation and insight to laboratory
research and discovery, and to help return to the clinic a better understanding
of human disease: the bedside to bench to bedside cycle that moves both medicine and science forward.
As well as providing a better understanding
of human behavior and emotions, Dr Strelan's
research could help to inform
clinical psychologists and relationship counselors.
The study was supported by the Eunice Kennedy Shriver National Institute
of Child Health and
Human Development (K23 HD054720), Flora Family Foundation, UCSF Catalyst Award, UCSF Resource Allocation Program, Brain & Behavior
Research Foundation Young Investigator Award, Stanford University Lucile Packard Foundation for Children's Health, Spectrum Child Health &
Clinical and Translational Science Award and the Extraordinary Brain Series
of the Dyslexia Foundation.
Contributing to the work were researchers from the National
Human Genome
Research Institute (NHGRI), the National Institute
of Allergy and Infectious Diseases, the National Institute
of Arthritis and Musculoskeletal and Skin Diseases, the National Heart, Lung, and Blood Institute and the NIH
Clinical Center, all part
of NIH, along with their colleagues in Turkey and the United Kingdom.
«This class
of compounds produces profound changes in
human perception and consciousness, and essentially it's been taken off the
clinical research bench for 40 years — it's almost unthinkable,» he says.
Using simple statistics, without data about published
research, Ioannidis argued that the results
of large, randomized
clinical trials — the gold standard
of human research — were likely to be wrong 15 percent
of the time and smaller, less rigorous studies are likely to fare even worse.
Researchers at the National
Human Genome
Research Institute (NHGRI), part
of NIH, validated the same biomarkers in 46 patients with MMA seen at the NIH
Clinical Center.
For the first time, a
research team led by Dr. Ralf Gilsbach and Prof. Dr. Lutz Hein from the Institute
of Experimental and
Clinical Pharmacology and Toxicology at the University
of Freiburg have mapped out the gene regulators in the DNA
of human cardiac muscle cells.
While more
research is needed to determine whether these approaches could help PD patients, Dr. Greenamyre is optimistic that one or both may ultimately make it into
human clinical trials in an effort to slow or halt the otherwise inevitable progression
of PD.
Department
of Health and
Human Services (DHHS)-- bridging the missions
of NIH with AHRQ and the Food and Drug Administration (FDA) and integrating traditional NIH
clinical research with health services, outcomes, and medical - effectiveness
research.
Melina R. Kibbe, M.D.,
of the University
of North Carolina at Chapel Hill (formerly
of Northwestern University, Chicago), and Editor, JAMA Surgery, and colleagues conducted a study to determine if sex bias exists in
human surgical
clinical research, if data are reported and analyzed using sex as an independent variable, and to identify specialties in which the greatest and least sex biases exist.
They have the opportunity to be exposed to a wide variety
of clinical and patient - oriented
research, from Phase I, II, and III trials to collection
of samples and
clinical data used to identify genetic variation that leads to
human disease.
«We still have a long way to go and many challenges to overcome before we will have therapies that are ready for
clinical use, but this is a significant first step in the process,» says Emdad, member
of the Cancer Molecular Genetics
research program at Massey, assistant professor in the VCU Department
of Human and Molecular Genetics and member
of the VIMM.
The
research, published online today in the journal
Clinical Infectious Diseases, shows that poultry may be a source
of human exposure to MRSA, a superbug which can cause serious infections and even death.
Bristol - Myers Squibb won its citation «for extending and enhancing
human life through innovative pharmaceutical
research and development, and for redefining the science
of clinical study through groundbreaking and extremely complex
clinical trials that are now recognized as industry models.»
Her
research is both translational and
clinical in nature and centers on the
human genetics
of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin cancers.
«The use
of a mouse tumor - derived matrix would limit any future applications
of these organoid technologies in
humans, and this work opens the door to
research directed specifically for
clinical applications,» noted Asma Nusrat, study co-author and the Aldred Scott Warthin Professor and Director
of Experimental Pathology in the University
of Michigan's School
of Medicine.
Ian Hindmarch, head
of the
Human Psychopharmacology
Research Unit at the University
of Surrey, thinks it is «cynical» to turn the normal process
of ageing into a
clinical condition deserving some kind
of therapy.
«The ultimate goal
of this
research will be to advance HIF - 1alpha stabilizers toward
clinical trials in
humans, using versions
of the drug that can be taken orally and reach the urinary tract,» Nizet said.