These studies may shed new light on the fundamental mechanisms of aging, and may open new avenues to the
treatment of human diseases associated with premature aging.
His team has developed statistical methods, computational algorithms and software that facilitate quick, accurate analysis of genetic
studies of human disease.
His research focuses on the cancer biology, drug resistance, and signaling pathway networks
of human diseases as well as on ways to model these disorders.
Cell size and cell number regulation are crucial elements of both organ size determination and control
of human diseases such as cancer and diabetes [26].
This will allow to understand more about genes we currently know very little about, and open up new avenues for research into the
genetics of human disease.
Because the fly modeled the key
features of the human disease, researchers can now screen proteins and molecules quickly to see which might have therapeutic effects.
Instead we can use models to look at the functions of genes involved in maintaining healthy organisms in order to obtain vital clues about the causes and
progression of human diseases.
Both of these gene - editing breakthroughs offer incredible new precision in developing targeted treatments for a vast
array of human diseases that are founded on single genetic mutations.
More from this series: How mouse research could be limiting our
knowledge of human disease, and the one mouse who rules over all other mice.
Although we are quite in the dark about the
why of human disease and suffering, ordinary observation can show us that the result of their occurrence is by no means necessarily evil.
Medical researchers believe that stem cell treatments have the potential to change the
face of human disease and alleviate suffering.
Now we could hopefully apply the same technique — not so much for animals and agriculture — but for treating a long
list of human diseases.
We advocate instead to embrace the complexity and have developed approaches that allow us to uncover the underlying causes
of human diseases no matter how complex.
The convergence of technological advances puts the formerly unthinkable within the grasp of scientific inquiry, offering unparalleled opportunities to understand the
physiology of human disease and to find new ways to treat it.
Researchers have managed to insert that gene into mice to make a living, breathing
model of a human disease that mice would otherwise never acquire.
Future
treatment of human disease will increasingly move from a «one size fits all» approach to one of tailoring the treatment to the individual patient.
The study of viruses far removed from human concerns has brought to light powerful tools for the
study of human disease.
These DNA — based tests were originally developed to study the
basis of human diseases and became available for dogs in 2007.
These cells can potentially turn into many different types of cells, and offer staggering potential for treating a huge
range of human diseases.
From accelerating the identification and validation of novel therapeutic targets, to creating better animal models
of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.
The fruit fly shares a significant degree of similarity to humans and can be used to model a
number of human diseases including Alzheimer's, Parkinson's, cancer, obesity, diabetes, heart disease, epilepsy, ALS, mental illness, and more.
«Now that we can precisely investigate receptor - G protein interactions in living cells, we hope that this will lead to the development of new drugs for a
variety of human diseases with better efficacy and less side effects.»
Dr. Torkamani's research covers a broad range of areas centered on the use of genomic technologies to identify the genetic etiology and underlying
mechanisms of human disease in order to define precision therapies for diseased individuals.
Demonstrated that ABOBEC3G, in conjunction with RNA granules, functions to regulate endogenous mobile genetic elements (e.g., Alu RNAs), whose mobility contributes to a variety
of human diseases including cancers and leukemias.
To succeed as a clinician - researcher, a physician - scientist uses his or her mastery of both clinical practice and basic science research in parallel, often drawing on both skill sets to find advances in the diagnosis, treatment, and
prevention of human disease.
In addition to the chemical legacy carried by modern people, the book focuses particularly on the growing threat of zoonoses — diseases that jump from animal to human — that can arise from the incursion of people on wild habitats: Of the 58
percent of human diseases caused by germs, 816 of 1,407 known human pathogens emerge from wild animal populations.
Mitalipov says his goal is to engineer better primate models
of human disease by cloning adult rhesus monkey cells that have been genetically altered to mimic neurological and other disorders that are otherwise difficult to study in living humans or other animals.
For their seminal contributions to concepts and methods of creating a genetic map in the human, and of positional cloning, leading to the identification of
thousands of human disease genes and ushering in the era of human genetics.
Furthermore, new genome - editing technologies such as CRISPR / Cas9 now enable the efficient derivation of precision disease models incorporating patient - specific genetic variants as a means of recapitulating essential
aspects of human disease in mouse and other model organisms.
Phrases with «of human disease»