He is interested in elucidating mechanisms
of human disease by exploring the functional effects of genetic variation through computational analysis of «- omic» sequencing data.
Not exact matches
But with the exception (perhaps)
of some infections,
human disease, including lung cancer, is rarely «caused»
by one (and only one) thing.
Founder and CEO Social Capital LP and Golden State Warriors Owner Chamath Palihapitiya has a mission which is, «To advance humanity
by solving the world's hardest problems including the advancement
of human capital, the eradication
of disease, solutions to global climate change, and other really difficult things that are non obvious.»
In March, the Committee for Medicinal Products for
Human Use (CHMP)
of the European Medicines Agency (EMA) adopted a positive opinion to include a new indication for adults with established atherosclerotic cardiovascular
disease (myocardial infarction, stroke or peripheral arterial
disease) to reduce cardiovascular risk
by lowering LDL - C levels.
This approach begins
by using tools like advanced
human genetics to unravel the complexities
of disease and understand the fundamentals
of human biology.
The research was conducted
by dozens
of international health and environmental experts and incorporates data from the ambitious Global Burden
of Disease project, which highlighted how smoking, blood pressure, poor diet, and environmental factors affect
human health earlier this year.
What an American doctor trained on the mainland might see as a case
of the flu could actually be Chikungunya, a viral
disease transmitted to
humans by infected mosquitoes.
InvivoSciences will continue to contribute to the improvement
of human health
by establishing a new paradigm for discovering drugs that focus on
diseases with limited treatment options such as cardiac fibrosis, scleroderma, and lupus in a time - effective manner while remaining safe and cost effective.»
The presence
of the AIDS virus in an asymptormatic carrier
of the
disease may be indicated
by a blood test designed to detect the
human immunodeficiency virus (HIV) antibodies.
Although we are quite in the dark about the why
of human disease and suffering, ordinary observation can show us that the result
of their occurrence is
by no means necessarily evil.
To lift the economic burdens which depress life and spoil opportunity, to liberate folk from the slavery
of their
diseases, to set men free
by education from the Town
of Stupidity, which, as Bunyan rightly says, is only four degrees north
of the City
of Destruction itself — all these endeavors to give persons a chance to be their best selves are crusades for
human emancipation and happiness.
The
Human Genome Project, not long ago completed at a cost
of $ 3 billion, was often presented
by its promoters as opening the way to discovering the ultimate genetic causes
of all
diseases, thus setting the stage for their cure.
How were the firstborns to die — tangible murder, or a
disease brought about
by poor birthing conditions engineered
by the medical community
of the time, or
by a pulse from the Anananunki planet that could be attributed to a weak, ineffectual god assigned to this sector
of the universe and passed off as omnipotent because He thought he was, or knew he had to pretend to be, to give
humans Any Hope AT ALL?
Indeed in agriculture and in
human and animal health,
diseases are now forestalled wherever possible,
by such methods as the application
of trace elements to the soil, sterilization, a balanced diet and immunization.
All
human beings face death as an inevitable destiny, but those
of us who are crippled
by heart
disease or cerebral injury or other illness are more conscious
of this destiny, particularly as we advance in years.
Such an attention getting event might be the simultaneous and overnight, 1) world wide total and permanent remission
of all cancers, 2) world wide regeneration
of limbs
of all amputees, 3) world wide total cessation
of sëx trafficking
human abuse, 4) world wide total cessation
of child abuse, 5) world wide cessation
of all hostilities, 6) world wide sudden curing
of diseases cause
by genetic defects.
In reality, the amount
of protein associated with optimal
human health, as supported
by science and epidemiology (the incidence
of disease amongst various populations), is much lower than you think.
An infectious
disease caused
by type - A strains
of the influenza virus that is transmittable from birds to
humans.
We help protect our Australia's productive industries, environment and
human health from pests and
diseases by assessing the risks they pose, prioritising the pathways
of entry and providing new technologies for surveillance and early response through sensor networks and autonomous platforms.
If any
of these components is reduced in food products and
human consumption these will leads to the Deficiency
diseases for example Kwashiorkor and Marasmus caused
by the deficiency
of dietary proteins.
Such standards help eliminate product contamination
by any number
of microorganisms known to cause dangerous infection and
disease in
humans.
I've read (in Scientific American I believe) recent research suggesting that H Pylori helps regulate the
human immune system (for its own gain,
of course, but ours too
by suppressing auto - immune
diseases).
The author, a renowned researcher in this field for almost 50 years, addresses bacterial colonization
of the newborn, protection against
disease that is provided
by breastfeeding, infectious agents in
human milk and their impact on breastfeeding, and much more.
Funding / Support: The Infant Feeding Practices Study II was funded
by the Food and Drug Administration, Centers for
Disease Control and Prevention, Office
of Women's Health, National Institutes
of Health, and Maternal and Child Health Bureau in the US Department
of Health and
Human Services.
Findings
of the research, published April 22 in the journal Mucosal Immunology, reveal that a substance found in animal and
human breast milk called epidermal growth factor, or EGF, blocks the activation
of a protein responsible for unlocking the damaging immune cascade that culminates in NEC, a
disease marked
by the swift and irreversible death
of intestinal tissue that remains one
of the most - challenging - to - treat conditions.
In
human terms, the costs
of lives and families damaged
by heart
disease, strokes, cancer and lung
disease are incalculable.
Former EPA Region 2 Administrator Judith Enck, who was featured in the Politico article and is also a regular voice on WAMC, called the actions
by EPA and the Department
of Defense «scientific censorship»
of the report being compiled
by the Department
of Health and
Human Services» Agency for Toxic Substances and
Disease Registry.
A panel
of ethicists convened
by the U.S. National Academies
of Medicine and Science also staked out that position in February, ruling that
human germline engineering might someday be permissible for correcting
diseases, but only if there are no alternatives and not for enhancements.
«Now, using genomic methods that were not available 10 years ago, it appears that components made
by the virus interact with
human DNA in the places where the genetic risk
of disease is increased,» Harley says.
A study
by researchers at the University
of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel
disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition
of the colon that resembles
human IBD.
That's going to have a significant impact on
human health,
by reducing risk for many types
of diseases and
by promoting wellness.»
Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the study
of molecules to treat cancers caused
by human herpes virus infection in mice models
of disease.
Ocean seagrass meadows reduce bacteria unhealthful to
humans and marine organisms
by up to 50 %, a new study shows, and they also decrease the likelihood
of disease in coral reefs
by half.
Degenerative brain
diseases like mad cow
disease (officially known as bovine spongiform encephalopathy, or BSE), scrapie in sheep, and vCJD in
humans are thought to be caused
by prions, misfolded versions
of a normal cellular protein called PrPC.
Studies on the origins
of BSE — a fatal
disease marked in the early stages
by loss
of balance — gained urgency with the 1996 emergence in
humans of the BSE - like new variant Creutzfeldt - Jakob
disease (nvCJD).
This is typical Rothschild: considering the bends not as a
human ailment, first documented
by a miner in 1841, but as a vertebrate's
disease, one that can be tracked backward through more than 200 million years
of mammalian evolution.
A joint work
by EPFL, ETH Zürich and the CHUV has identified a pathological process that takes place in both mice and
humans towards one
of the most common
diseases that people face in the industrialized world: type 2 diabetes.
IN A rare instance
of humans beating one
of the impacts
of climate change, measures to combat malaria appear to be neutralising the expected global increase
of the
disease driven
by rising temperatures.
The study
of these highly unusual but devastating prion
diseases has to date been thwarted
by a lack
of animal models that faithfully mimic the
disease processes in
humans.
By directly manipulating a portion
of the prion protein - coding gene, Whitehead Institute researchers have created mouse models
of two neurodegenerative
diseases that are fatal in
humans.
Today's guidance, written
by a group
of cervical cancer screening experts led
by University
of Alabama at Birmingham gynecologic oncologist Warner Huh, M.D., is being published simultaneously in the journals Gynecologic Oncology, Obstetrics & Gynecology, and the Journal
of Lower Genital Tract
Disease under the title «Use
of Primary High Risk
Human Papillomavirus Testing for Cervical Cancer Screening: Interim Clinical Guidance.»
A medical doctor (
of human patients), Rothschild is often sought out these days
by paleontologists for his observations about the
diseases revealed in bones (the dinosaur kind)-- and the subsequent deductions about how these long - extinct creatures might have lived.
He carried one genetic mutation that in modern
humans raises the risk
of coronary heart
disease by 40 per cent, and two others that made him prone to a build - up
of fat in the linings
of his arteries.
If dozens
of human and animal studies published over the past six years are borne out
by large clinical trials, nicotine — freed at last
of its noxious host, tobacco, and delivered instead
by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety
of neurological disorders, including Parkinson's
disease, mild cognitive impairment (MCI), Tourette's and schizophrenia.
The study, led
by Nancy J. Cox
of the Centers
of Disease Control and Prevention describes a molecular analysis
of the novel influenza A (H1N1) virus infecting
humans in several parts
of the world.
If further studies in
humans prove successful, this research could have broad implications for the prevention
of influenza and,
by extension, as an approach for other infectious
diseases as well.
These techniques include:
human tissue created
by reprogramming cells from people with the relevant
disease (dubbed «patient in a dish»); «body on a chip» devices, where
human tissue samples on a silicon chip are linked
by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses
of drugs given to volunteers allow scientists to study their metabolism in
humans, safely and with unsurpassed accuracy.
The most serious forms
of the
disease are caused
by Plasmodium falciparum and Plasmodium vivax, but other related species (Plasmodium ovale and Plasmodium malariae) can also infect
humans.
This surely contributes to the rarity or nonexistence
of human - to -
human transmission
of rabies (acquired
by the bite
of an infected dog or bat); cat - scratch
disease (which causes skin lesions and swollen lymph nodes); tularemia (a
disease, often acquired when hunting and cutting up an infected rabbit, that can cause skin ulcers, swollen lymph nodes, and fever); and BSE (probably acquired
by eating the nervous system tissue
of infected cows).
Human hematopoietic stem and progenitor cells (HSPCs), derived from bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed
by a variety
of diseases.