In April of 2004, a letter bearing 206 signatures of Members of the United States House of Representatives was sent to President George Bush, asking him to increase the number
of human embryonic stem cell lines that should be eligible for public funding.
An important concept in this research is pluripotency ---- the ability
of the human embryonic stem cell to differentiate or become almost any cell in the body, explained senior author Kenneth S. Kosik, professor in the Department of Molecular, Cellular & Developmental Biology (MCDB).
Dr Harris normally took a libertarian stand on bioethical issues and was a forceful and reliable supporter
of human embryonic stem cell research, abortion, euthanasia, anonymous sperm donation, IVF for lesbians and single parents and so on.
In April 2004, more than 200 members of the U.S. House of Representatives sent President Bush a letter, asking him to increase the number
of human embryonic stem cell lines that should be eligible for public funding.
Robert Klein, chairman of the CIRM bragged that the grants «make us the highest funder
of human embryonic stem cell research in the world.»
The National Institutes of Health (NIH) has allowed a contract for the dissemination of embryonic stem cell lines approved for US government funding to lapse, shuttering a key stem cell bank, and doubling the price researchers pay for samples
of some human embryonic stem cell (hESC) lines.
«The Ethics
of Human Embryonic Stem Cell Research.»
Federal officials have approved the start
of human embryonic stem cell treatment experiments on patients suffering a leading cause of vision loss.
To determine how valid the objection against funding
of human embryonic stem cell research is because of its use of human embryos, it's important to understand two key aspects of hESCs» unique biology and derivation.
The backgrounder below provides summary main points and sources on the position of current NIH Director Dr. Francis Collins in support
of human embryonic stem cell research, human cloning, and the creation of ethically - questionable human - animal chimeras.
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair
of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.
Non-cardiomyocytes influence the electrophysiological maturation
of human embryonic stem cell - derived cardiomyocytes during differentiation.
Daley, the associate director of the stem cell programme at Children's Hospital Boston, decried his opponents» portrayal
of human embryonic stem cell research as replaceable with adult stem cell research or work on induced pluripotent cells.
By Young Chung, Irina Klimanskaya, Sandy Becker, Tong Li, Marc Maserati, Shi - Jiang Lu, Tamara Zdravkovic, Dusko Ilic, Olga Genbacev, Susan Fisher, Ana Krtolica, and Robert Lanza To date, the derivation
of all human embryonic stem cell (hESC) lines has involved destruction of embryos.
Immunological properties
of human embryonic stem cell - derived oligodendrocyte progenitor cells.
For the first time since the linkurl: National Institutes of Health; http://www.nih.gov/ released its new guidelines for the derivation
of human embryonic stem cell (hESC) lines last summer, a line approved under the Bush administration has been recommended for inclusion into the growing federal registry of lines eligible for federal funding.
Modification
of human embryonic stem cell - derived dendritic cells with mRNA for efficient antigen presentation and enhanced potency.
Preclinical Safety
of Human Embryonic Stem Cell - Derived Oligodendrocyte Progenitors Supporting Clinical Trials In Spinal Cord Injury.
Expansion and maintenance
of human embryonic stem cell - derived endothelial cells by TGFbeta inhibition is Id1 dependent.
I pray for the day when James A. Thomson and others in favor
of human embryonic stem cell research think about it enough to be totally uncomfortable.
At the International Society for Stem Cell Research 2017 Annual Meeting (June 14 - 17, 2017; Boston, USA), Asterias Biotherapeutics, Inc (CA, USA) will present new 9 - month efficacy and safety data from their ongoing SCiStar Phase I / IIa trial
of human embryonic stem cell - derived oligodendrocyte progenitor cells.
Maturation
of human embryonic stem cell - derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice.
In The Language of God, Collins included an appendix in which he explicitly dealt with the morality
of human embryonic stem cell research.
The long - awaited registry
of human embryonic stem cell lines approved by the National Institutes of Health (NIH) went up on the Web this week.
Upton lamented «a major gap between the science of cures and the way we regulate these therapies,» and DeGette, an outspoken supporter
of human embryonic stem cell research, vowed to «take a comprehensive look» at how Congress might intervene.
They used the gene editing technology CRISPR to engineer a series
of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.
But though stem cell research in general is booming in Germany, the political implications
of human embryonic stem cell research remain unresolved.
In 2004 Blackburn and ethicist William F. May made headlines when the Bush administration ousted them from the President's Council on Bioethics for their strong public support
of human embryonic stem cell research.
This barrier has been highly visible in the field
of human embryonic stem cell research, where researchers in the United States must adhere to legislation and funding limitations that researchers in European countries have not faced.
He has also been an inveterate foe of abortion, a position that informed his repeated votes against expanding the number
of human embryonic stem cell lines available to NIH - funded researchers during the George W. Bush administration.
Congressional supporters of stem cell research have re-introduced legislation to codify President Barack Obama's 2009 executive order lifting restrictions on the number
of human embryonic stem cell lines available to federally funded researchers.
The National Institutes of Health (NIH) has allowed a contract for the dissemination of embryonic stem cell lines approved for US government funding to lapse, shuttering a key stem cell bank, and doubling the price researchers pay for samples
of some human embryonic stem cell (hESC) line... from $ 500 per vial of frozen cells to $ 1,000.
A few weeks ago we all heard the announcement of a major scientific breakthrough that allowed scientists to create the equivalent
of human embryonic stem cells (called induced pluripotent stem cells) but without using or destroying embryos.
The creation of the Centre of Regenerative Medicine in Barcelona (CMRB) reflects «a change in the Spanish public policy regarding derivation and use
of human embryonic stem cells (HESC), based on a progressive evolution of the public awareness and sensibility of the Spanish [citizenry],» says CMRB Director Juan Carlos Izpisúa Belmonte in an e-mail.
The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line
of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.
Finding may enhance understanding
of human embryonic stem cells and lead to better models for regenerative therapies
The Bundestag faces a heated debate on 30 January, when the issue of whether to allow the import
of human embryonic stem cells for research purposes is on the agenda.
The ethics council finally issued its 20 - page report just before Christmas, voting in favor of allowing the import
of human embryonic stem cells, under certain conditions, by a small majority of 15 to 9, paving the way for next week's final showdown.
In work published on 24 November in the journal Nature biotechnology, Anselme Perrier's team at I - Stem identified a recurrent anomaly in the genome
of human embryonic stem cells left in culture for too long.
Dominant - Negative Effects of Adult - Onset Huntingtin Mutations Alter the Division
of Human Embryonic Stem Cells - Derived Neural Cells.
For the first time, through the use
of human embryonic stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystrophy.
[6] S.A. Kuznetsov, N. Cherman, P.G. Robey, «In vivo bone formation by progeny
of human embryonic stem cells,» Stem Cells Dev, 20:269 − 87, 2010.
Synthetic peptide - acrylate surfaces for long - term self - renewal and cardiomyocyte differentiation
of human embryonic stem cells.
High Throughput Screening for Inhibitors of Rest in Neural Derivatives
of Human Embryonic Stem Cells Reveals a Chemical Compound that Promotes Expression of Neuronal Genes
An eye implant made of a thin sheet
of human embryonic stem cells could be considered as an effective treatment for a common form of vision loss.
By: Sadhana Agarwal, Katherine L. Holton, Robert Lanza Differentiation
of human embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that mimic in vivo embryonic developmental programs.
Forced aggregation of defined numbers
of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.
Dr. Garcia - Perez has expertise in the field
of human embryonic stem cells, human embryonic carcinoma cells, induced pluripotent stem cells, and neuronal stem cells.
«The current extension of induced pluripotency to human cells is a major development and although it is early days for this technique it may well prove to be every bit as signifcant as the first derivation
of human embryonic stem cells nine years ago.
iPSCs are cells that were originally from adult tissues, but have been forced to produce proteins that are thought to be essential for the pluripotency
of human embryonic stem cells.