Sentences with phrase «of human genome»

The result: the finch genome is about one - half the size of the human genome, or about 1.5 billion base pairs.

Known formally as Callorhinchus milii, the elephant shark boasts an incredibly compact genome — about a billion DNA base pairs, roughly one - third the length of the human genome.

In order to understand gain and loss dynamics we must be able to correctly assign this non-aligning portion of the human genome as either human gain or mouse loss.

Following the completion of the Human Genome Project in 2001, scientists and the media described the genome as «the book of life», holding the answers to the way genes are linked to disease.

Ultimately, given that we are able to detect little phenotypic impact where there are vast amounts of DNA turnover, our findings support lower estimates for the functional proportion of the human genome.

Ascertainment bias in studies of human genome - wide polymorphism Clark, A. G., M. J. Hubisz, C. D. Bustamante, S. H. Williamson et al. 2005.

Initial sequencing and analysis of the human genome.

We need more studies like these (and ENCODE) to fully understand the function of the human genome.

DNA loss via deletion also plays a role, with approximately 650 Mb of the human genome being lost over the same time period [4].

Ascertainment bias in studies of human genome - wide polymorphism.

Reykjavik, ICELAND, 25 September 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer.

In the post-genomic era, we are witnessing significant advances in the functional decipherment of the human genome sequence that have been made possible by new technological developments in the field of genomic medicine.

This map provided a template for completing the final assembly of the sequence of the human genome.

«The sequencing of the human genome has helped reveal genetic mutations that lead to thousands of devastating diseases, most of which are untreatable,» says Dr. Zhang.

«It shares the structure and many features of the human genome; many human proteins function just as well in fruit flies.

While the HapMap was ramping up, I got my name on a paper for the first time, High - density single - nucleotide polymorphism maps of the human genome (Genomics, 86:2, 2005).

Researchers from ERIBA, Radboud UMC, XJTU, Saarland University, CWI and UMC Utrecht have made a big step towards a better understanding of the human genome.

On the tenth anniversary of the sequencing of the human genome, what is that remarkable feat's legacy, and what does it mean for the future?

Using transcription and DNA binding to identify functional DNA, the ENCODE consortium estimated that as much as 80 % of the human genome might be functional [30].

With the complete sequence of the human genome a reality, and with a growing body of transcriptomic, proteomic, and metabolomic data sets in health and disease, we are now in a unique position in the history of medicine to define human disease precisely, uniquely, and unequivocally, with optimal sensitivity and specificity.

Each of the working groups is responsible for developing a proposal for a set of genomes to sequence that would advance knowledge in one of three important scientific areas: identifying areas in genetic research where the application of high - throughput sequencing resources would rapidly lead to significant medical advances; understanding of the human genome; and understanding the evolutionary biology of genomes.

To gain a comprehensive view of the human genome and biological systems, they instead had to work in a highly integrated fashion.

Since the completion of the human genome an important goal has been to elucidate the function of the now known proteins: a new molecular method enables the investigation of the function for thousands of proteins in parallel.

Scientists are now contemplating the fabrication of a human genome, meaning they would use chemicals to manufacture all the DNA contained in human chromosomes.

This has provided researchers with a powerful tool for understanding the structure and function of the human genome.

The genome of wheat is nearly three times the size of the human genome.

Researchers are exploring the use of new technologies for uncovering genetic variations in humans and for closing gaps in the mapping of the human genome.

This has proven to be one of the most powerful ways of identifying the parts of the human genome that are most functionally important, and therefore most likely to be relevant for an understanding of disease.

«As the dissent from today's decision explains, pieces of the human genome are not patentable,» said Daniel B. Ravicher, executive director of PUBPAT and co-counsel in the lawsuit.

«The availability of the human genome sequence, as well as other genomic resources produced by our sequencing centers, has transformed biomedical research everywhere,» said NHGRI's Associate Director of Extramural Research Jane Peterson, Ph.D., who is also a program director for NHGRI's Large - Scale Sequencing Research Network.

The research that has pinpointed these biologically «conserved» regions on the two genomes allows researchers to focus on the important parts of the human genome, and to ignore the much larger amounts of genetic information that is essentially meaningless — some biologists call it «junk» DNA.

More recently, scientists have identified parts of the human genome carrying Neandertal genetic variants, but — in part because Neandertal - derived DNA is so hard to identify and also because of the expense of performing tests for its influence on individuals — scientists still don't fully understand how Neandertal - derived variants influence modern human traits.

If you took high school biology in the «00s, you probably heard about the completion of the human genome sequence.

3 Billion Approximate length of the human genome in base pairs (letters of the DNA sequence).

The team used ChromEMT to image and measure chromatin in resting human cells and during cell division (mitosis) when DNA is compacted into its most dense form — the 23 pairs of mitotic chromosomes that are the iconic image of the human genome.

Using a specific work flow, they assessed both the coding and noncoding regions of the human genome, including the evaluation of highly polymorphic SNPs, structural and copy number variations, as well as 69 control genomes sequenced by the same procedures.

The sequencing of the human genome (ScienceNOW, 14 April 2003:) gave scientists major new insights into what makes us human: Although we share more than 98 % of our genetic code with the chimpanzee, natural selection has turned us into a very different animal than the chimps, from whom our hominid ancestors split evolutionarily some 6 million years ago (ScienceNOW, 31 August).

«We're really hoping to use the fruits of the human genome project,» Henderson says.

Approximately 8 % of the human genome is made up of DNA from viruses that slipped in their genetic material as our ancestors evolved.

Francis Collins, head of the Human Genome Project and a devout Christian, calls Hamer's claim «wildly overstated.»

Their discovery had to wait for the sequencing of the human genome and other advances in gene - finding techniques.

All in all, the virus - like components of the human genome amount to almost half of our DNA.

Colored in blue are the 46 chromosomes of the human genome.

It is surprisingly large — about three times the size of the human genome.

RESEARCH FOCUS Creating an encyclopedia detailing what the most mysterious parts of the human genome do

Yesterday's White House ceremony announcing the near completion of the human genome was more than a celebration of «an epic - making triumph of science and reason,» as President Clinton called it.

«This work is a great example of how knowledge of the human genome sequence can lead to valuable insights into human diseases.

Recently, for example, talks broke down between Celera and a group of nonprofit centers over how they might collaborate on completing the sequence of the human genome.

In 2000, when scientists of the Human Genome Project presented the first rough draft of the sequence of bases, or code letters, in human DNA, the initial results appeared to confirm that the vast majority of the sequence — perhaps 97 percent of its 3.2 billion bases — had no apparent function.

On 14 March, the two leaders announced that they enthusiastically support the rapid release of human genome sequence data, a principle long advocated by Francis Collins, director of the National Human Genome Research Institute (NHGRI), and other scientists in the nonprofit sector.