Sentences with phrase «of human genome sequence»

In the postgenomic era, the availability of human genome sequence for genome - wide analysis has revealed higher - order architectural features (i.e., beyond primary sequence information) that may cause genomic instability and susceptibility to genomic rearrangements.

«The availability of the human genome sequence allows scientists to scan sequences to identify kinases, and the increased speed with which DNA can be sequenced enables us to rapidly search for mutations in those kinases in human cancers,» said Markowitz.

As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed > 98 Mb (approximately 3.3 %) of the human genome sequence.

«The availability of the human genome sequence, as well as other genomic resources, has profoundly affected biomedical research and thinking.

«But with the completion of the human genome sequence and the availability of the kinome, one can begin to think about how to do this in a much wider and unbiased sense.»

Francis Collins, director of the National Human Genome Research Institute, predicts that 90 percent of the human genome sequence will be available by the spring of 2000, with a complete human DNA sequence available in 2002 or 2003.

«During the early debates about the Human Genome Project, researchers had predicted that only a few percent of the human genome sequence encoded proteins, the workhorses of the cell, and that the rest was junk.

In the post-genomic era, we are witnessing significant advances in the functional decipherment of the human genome sequence that have been made possible by new technological developments in the field of genomic medicine.

«The availability of the human genome sequence, as well as other genomic resources produced by our sequencing centers, has transformed biomedical research everywhere,» said NHGRI's Associate Director of Extramural Research Jane Peterson, Ph.D., who is also a program director for NHGRI's Large - Scale Sequencing Research Network.

If you took high school biology in the «00s, you probably heard about the completion of the human genome sequence.

«This work is a great example of how knowledge of the human genome sequence can lead to valuable insights into human diseases.

On 14 March, the two leaders announced that they enthusiastically support the rapid release of human genome sequence data, a principle long advocated by Francis Collins, director of the National Human Genome Research Institute (NHGRI), and other scientists in the nonprofit sector.

Since the publication of the human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.

So declared President Bill Clinton in the East Room of the White House on June 26, 2000, at an event held to hail the completion of the first draft assemblies of the human genome sequence by two fierce rivals, the publicly funded international Human Genome Project and its private - sector competitor Celera Genomics of Rockville, Md..

And with the recent unveiling of the human genome sequence — to say nothing of the new drugs that are being tested every day — those working in the patent field are busier than ever.

«Most of the human genome sequence is now known, but we still don't know what most of these sequences mean,» said Sheng Zhong, bioengineering professor at the UC San Diego Jacobs School of Engineering and the study's lead author.

Not exact matches

Venter, who is one of the first people to sequence the human genome, co-founded the company in effort to discover early genetic markers for a variety of disorders.

To do all this, Human Longevity will build a human sequencing operation capable of processing 40,000 human genomes a Human Longevity will build a human sequencing operation capable of processing 40,000 human genomes a human sequencing operation capable of processing 40,000 human genomes a human genomes a year.

The commercialization of DNA sequencing (the reading of an organism's code) and synthesis (the writing of that code) has accelerated since the mapping of the human genome was completed in 2003.

Aug. 30, 2012: The genome of a recently discovered branch of extinct humans known as the Denisovans that once interbred with us has been sequenced

The entire genome of the tiny nematode (Caenorhabditis elegans) also has been sequenced as a ta - ngen = tial study to the human genome project.

The, members of the workshop believe that knowledge gained from mapping and sequencing the human genome can have great benefit for human health and well being.

Dec. 18, 2013 — The most complete sequence to date of the Neanderthal genome, using DNA extracted from a woman's toe bone that dates back 50,000 years, reveals a long history of interbreeding among at least four different types of early humans living in Europe and Asia at that time, according to University of California, Berkeley, scientists.

Aug. 30, 2012: The genome of a recently discovered branch of extinct humans known as the Denisovans that once interbred with us has been sequenced Anyone find fossils of Adam and Eve yet?

In June 2000 he and Craig Venter of the rival commercial project were able jointly to announce the entire sequencing of the human genome.

A human - chimp comparison revealed some 35 million mutations in the single units of the overall sequence and also found about 5 million additions to or subtractions from the genome involving chunks of DNA sequence.

The point being that nobody knows how different the intron or non-protein coding sequences are between humans and other primates because the research quoted is only on the exons, or protein coding portions of the genome.

In sequencing of the human genome, we learned that diseases rarely correlated to specific human genes.

To determine how the cells switch from one type to another, they took three human uterine carcinosarcoma samples and sequenced the genomes of cells in two parts of each tumor: the carcinoma and sarcoma components.

The newly sequenced genome of the plague - causing bacterium Yersinia pestis suggests human adaptations are what have kept this disease in check

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

BOSTON — For bee researchers like May Berenbaum, 2006 was the year an international consortium of researchers published the first full sequence of the honeybee genome, offering a unique and long - sought glimpse at the biological quirks of an insect that shares a productive history with humans.

In February, researchers published the first ancient American human genome, sequencing DNA from the remains of a boy known as Anzick - 1, who was buried about 12,600 years ago in what is now western Montana.

Thanks to powerful gene - sequencing techniques developed in the past two decades during the race to decode the human genome, researchers are beginning to reconstruct what our ancestors» microbiomes looked like, potentially going back thousands of years.

The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

When the human genome draft was announced 10 years ago, many researchers and policymakers anticipated using the newly sequenced code to develop a wealth of diagnostic and treatment capabilities.

The man responsible for one of the original sequences of the human genome as well as the team that brought you the first living cell running on human - made DNA now hopes to harness algae to make everything humanity needs.

Their work has made it increasingly clear that for all the popular attention devoted to genome - sequencing projects, the epigenome is just as critical as DNA to the healthy development of organisms, humans included.

Taking advantage of the handful of complete human genome sequences now available, the pair looked at how alleles — the two copies of each gene we inherit from our parents — differ within a genome.

«Our work demonstrates that the generation of genome sequences from a large number of archaic human individuals is now technically feasible, and opens the possibility to study Neandertal populations across their temporal and geographical range,» says Janet Kelso, the senior author of the new study.

The Human Genome Project, which sequenced the 3 billion pairs of nucleotide bases in human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over Human Genome Project, which sequenced the 3 billion pairs of nucleotide bases in human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over human body and also change over time.

Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

The human genome contains millions of sequences derived from so - called transposable elements, genetic units that «jump» around the entire genome.

In addition to sequencing the woolly mammoth genome, Hendrik has reconstructed the diets of extinct giant sloths, debunked a hypothesis about the origin of human immunodeficiency virus (HIV) and sequenced the genome of the bacterium that caused Black Death.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

Moreover, data collected from whole - genome sequencing showed that Ata's molecular composition aligned with that of a human genome.

Now Pääbo and his colleagues have devised a new method of genetic analysis that allowed them to reconstruct the entire Denisovan genome with nearly all of the genome sequenced approximately 30 times over akin to what we can do for modern humans.

The sequencing of genomes of 48 bird species explains the evolutionary roots of vocalization and could offer insight into human speech disorders

New methods for the removal of contaminating DNA from microbes and present - day humans that were developed by the Leipzig group have now enabled the researchers to sequence the genomes of five Neandertals from Belgium, France, Croatia, and Russia that are between 39,000 and 47,000 years old.

Erwin compares the endeavor to the Human Genome Project, in which scientists mapped the sequence of our genes.