Sentences with phrase «of human germ»

Our dream is to use this model to make a genetic map of human germ - cell differentiation, including some of the very earliest stages.»

To that end, Saitou's team recreated the developmental process of human germ cells, which gives rise to reproductive sperm and eggs.

Dr. Frankel is currently directing or co-directing projects related to the ethical and policy implications of human germ - line interventions, the responsible use of animals in biomedical and behavioral research, improving patient safety and reducing errors in health care, the ethical dimensions of the Human Genome Diversity Project, the uses of anonymity on the Internet, and intellectual property and ethical standards for electronic publishing in science.

Not exact matches

Further Reading: The Rational Optimist - How Prosperity Evolves - Matt Ridley Guns, Germs & Steel - The Fates of Human Societies - Jared Diamond A Discussion on Modernization - Li Lu The Prospect of Value Investing in China - Li Lu Media and The Market - Mastersinvest The Coming Productivity Boom - Michael Mandel / Bret Swanson

Evolution explains the diversity of the planet's organisms, including the germs and the parasites that have caused so much human misery.

Whether supernatural or human, the germ idea of the church, I claim, is that global unity and community is not only possible but necessary.

She is the Mystical Body of Christ; at the same time a visible society instituted with hierarchical organs, and a spiritual community; the Church on earth, the pilgrim People of God here below, and the Church filled with heavenly blessings; the germ and the first fruits of the Kingdom of God, through which the work and the sufferings of Redemption are continued throughout human history, and which looks for its perfect accomplishment beyond time in glory.

In the light of man's unrelenting attack on disease, some biologists believe that development of deadly germs is a betrayal of the human race as well as of the ideals of science; one - hundredth of an ounce of botulism toxin could kill a million people, and its production seems to further neither scientific knowledge nor any peacetime applications.

Considering not morality and sin but only psychology and anthropology, we are compelled to notice that it is woman's soul that carries the germ of human ascent.

Prayer, like worship, is a purifying of self, a disinfecting of human life from the germs of false self - centeredness.

Germs / microbes / bacteria are FACT (they can be observed with a microscope), and then we have the germ theory of disease to explain why humans get sick due to gGerms / microbes / bacteria are FACT (they can be observed with a microscope), and then we have the germ theory of disease to explain why humans get sick due to germsgerms.

Human studies have even shown antibodies to wheat germ agglutinin in the serum of healthy individuals.

Now, humans don't eat, of course, purified wheat germ agglutinen, but the average person takes in between 10 - 20 mg per day of wheat germ agglutinen.

At any given moment, the unwashed human hand is covered with thousands of germs.

This finding also paves the way for practical applications: the ETH spin - off Malcisbo, which came from the microbiologist's laboratory, endeavours, on the basis of these surface sugar structures to develop novel vaccines against parasites and pathogenic germs for livestock and humans.

So far, preventing disease by employing CRISPR — Cas9 to alter the human germ line — a human embryo, egg or sperm — has remained extremely controversial, due to concerns about unwittingly introducing errors or leaving stowaway unedited disease - causing mutations that would put future generations at risk of disease.

Aside from well - established things like rabies virus, SARS coronavirus (the virus that causes severe acute respiratory syndrome) and Marburg virus (an extremely dangerous but rare hemorrhagic fever pathogen), bats appear to carry a plethora of other germs with unclear effects on human health, if any.

29 GENETICALLY MODIFIED SUPERHUMANS The debate over human germ - line engineering — reworking genes in the sperm and egg to create inheritable new traits — sputtered out early in the last decade after gene therapy had a series of notable failures.

Before birth, mouse and human ovaries contain an abundant supply of germ cells, some of which will develop into the eggs that will ultimately be released from follicles during ovulation.

«This is an important and fundamental paper for understanding human germ - line cells and finding the basic information about human germ - cell biology,» says reproductive biologist Evelyn Telfer of the University of Edinburgh, UK.

The researchers also observed that 6 - week - old germ cells created in the lab do not match a 6 - week - old human germ cell, suggesting that there is a blockage in the development of lab cells that scientists are failing to understand.

The first study of the development of such «germ cells» from humans could help scientists to learn how to create them in the laboratory instead.

But the summit's organizers concluded that actually trying to produce a human pregnancy from such modified germ cells or embryos, either through in vitro fertilization (IVF) with the sperm or eggs or the implantation of an embryo, is currently «irresponsible» because of ongoing safety concerns and a lack of societal consensus.

Primordial germ cells give rise to sperm or egg cells and, in humans, are already present in embryos at the second week of development.

The generation of human «lookalike» primordial germ cells is of importance for future fertility studies and the analysis of potential transgenerational epigenetic inheritance in humans.

The generation of human «lookalike» primordial germ cells is also of importance for future fertility studies and analysis of potential transgenerational epigenetic inheritance in humans.

Our side by side analysis uncovers the dynamics of epigenetic programming occurring in germ cell development at single base resolution in human and mouse cells.»

The theory: Millions of years ago, an ancient human ancestor contracted a retrovirus that inserted its DNA into the host's reproductive germ cells, passing the viral DNA down the ancestral line.

An editorial posted online on 28 April says the journal's objective in publishing the study was «the sounding of an alarm to draw immediate attention to the urgent need to rein in applications of gene - editing technologies, especially in the human germ cells or embryos.»

But other lipids are known to guide cell migrations in human brain development, and geneticist Ken Howard of University College London suspects HMG - CoA reductase might help produce a similar lipid molecule or modify a protein that attracts the germ cells.

Kyoto University scientists are casting light into the black box of human «germ cell» development.

Furthermore, there is very limited similarity to the human germ line V gene VH1 - 2 * 02 precursor of the VRC01 - like broadly neutralizing antibodies isolated from multiple patients.

The germ cells made from stem cells stopped differentiating in the mice before they produced mature sperm (likely because of the significant differences between the reproductive processes of humans and mice) regardless of the fertility status of the men from whom they were derived.

«We saw better germ - cell differentiation in this transplantation model than we've ever seen,» said Renee Reijo Pera, PhD, former director of Stanford's Center for Human Embryonic Stem Cell Research and Education.

Maternal age effect and severe germ - line bottleneck in the inheritance of human mitochondrial DNA Rebolledo - Jaramillo, B., M. S. Su, N. Stoler, J. A. McElhoe et al. 2014.

Establishment of a human embryonic germ cell line and comparison with mouse and human embryonic stem cells.

But we do know that, like other animals, the human embryo in its earliest stages consists of three main components known as germ layers: the ectoderm, the endoderm and the mesoderm.

Maternal age effect and severe germ - line bottleneck in the inheritance of human mitochondrial DNA.

Great Britain's Human Fertilisation and Embryology Authority (HFEA), which oversees fertility treatments and embryo research in that nation, recently approved fertility procedures that would amount to the genetic engineering of children through cloning (nuclear transfer) technology and germ - line modification, resulting in a «three - parent embryo» that would have genetic material from two mothers and one father.

Published in Human Molecular Genetics Ghiorzo P, Gargiulo S, Pastorino L, Nasti S, Cusano R, Bruno W, Gliori S, Sertoli MR, Burroni A, Savarino V, Gensini F, Sestini R, Queirolo P, Goldstein AM, Scarrà GB.Impact of E27X, a novel CDKN2A germ line mutation, on p16 and p14ARF expression in Italian melanoma families displaying pancreatic cancer and neuroblastoma Hum Mol Genet.

The human body is full of germs.

PRDM14 is required for the development of mouse germ cells [17], and also known as a pluripotent marker for mouse and human ES cells [17], [52].

Among the early germ cell markers examined, VASA is a candidate gene for detecting pre-meiotic germ cell differentiation from monkey ES cells, because its expression is detected earlier in the primordial stage of germ cell development in comparison to that of PIWI family genes in vivo in mice and humans [11], [36]--[38], [49].

A genome - wide study of allelic imbalance in human testicular germ cell tumors using microsatellite markers.

Human tissues exposed to either drug for one week in a dish had reduced numbers of cells that give rise to sperm and eggs, called germ cells, the study found.

He was the first to describe the successful culturing of human embryonic germ cells and published a landmark 1998 paper on human primordial germ cells.

Previous studies demonstrated the VASA expression to increase with germ cell differentiation from mouse and human ES cells by co-culturing with BMP4 - producing cells [57] and the addition of recombinant human BMP4 [6], respectively.

VASA is thus considered to be a valuable marker for the detection of germ cells in monkeys, as well as in mice and humans.

This is at the lower end of exome mutation rates previously estimated in parent - offspring trios, suggesting that post-zygotic mutations contribute little to the human germ - line mutation rate.

Germ cell specific markers are also expressed in embryoid bodies derived from human ES suggesting the presence of PGC's, so I am developing methods to enhance their formation and isolation.