Sentences with phrase «of human gut microbiota»

Over the last 10 to 15 years, the understanding of the composition and functions of the human gut microbiota has increased exponentially.

These continually expanding resources enable experimental investigation of the human gut microbiota, validation of hypotheses made with sequence - based analyses, and phenotypic characterisation of its constituent microbes.

«Reduction in dietary diversity impacts richness of human gut microbiota: Dietary diversity necessary for a healthy gastrointestinal microbiome.»

Heiman and Greenway describe how the reduction in dietary diversity has changed the richness of human gut microbiota, the community of microorganisms living in the gut.

In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers, using a commonly - found member of human gut microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.

Not exact matches

How do the microbes within cheese interact with the natural microbiota of the human gut and can cheese be used to assist in maintaining a healthy gut microbiota?

Using a «gnotobiotic mouse model» — where mice were «colonized with a synthetic human gut microbiota composed of fully sequenced commensal bacteria» — Desai et al reported on the effects of different diets with different fibre content.

Over 100 different oligosaccharides have been identified in the human colon, and recent research has shown that variations in the oligosaccharides within the mucus are associated with variations in the composition of the gut microbiota.

Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut microbiota in humans, and humans could be a good model to study the nutrition of dogs.

The Wyss team believes the ability of the human gut - on - a-chip to culture the microbiome with human gut cells also holds promise for the field of precision medicine, where a patient's own cells and gut microbiota could one day be cultured inside a gut - on - a-chip for testing different therapies and identifying an individualized treatment strategy.

As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.»

«Healthy gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or other diarrheal diseases permanently impact the microbiota, there could be long - term effects on human health,» explains Regina LaRocque, MD, MPH, of the Massachusetts General Hospital (MGH) Division of Infectious Diseases, co-senior author of the paper.

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Changes in the composition of the gut microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.

Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers» genetics, the composition of her breast milk and the development of her infant's gut microbiota.

In addition, cohousing coprophagic mice harboring transplanted microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected by human diets.

The goal of the study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice.

«It's increasingly clear that our gut bacteria, or microbiota, can communicate with the human brain,» said Kathy Magnusson, a professor in the OSU College of Veterinary Medicine and principal investigator with the Linus Pauling Institute.

A deep global analysis of the gut microbiota composition was done by phylogenetic microarray analysis using a Human Intestinal Tract Chip (HITChip), an analytical device designed specifically for studying gut bacteria.

Given that the investigators have previously shown the influence of the host molecular clock on the gut microbiota, they will also ask if taking this NSAID at different times of day might lead to higher efficacy and less side effects in animal models and eventually in humans.

Although the fucose findings are still preliminary, unlocking the role of this sugar in competitions between gut microbiota and pathogens could theoretically give rise to new therapies for treating human illness.

The findings illuminate the specialized roles played by key members of the vast microbial community living in the human gut, and could inform the development of tailored microbiota transplants to improve intestinal health after antibiotic use or illness.

The IMI could also control and organize access to metadata (the associated host disease phenotype data, for a human gut microbiota sample, for instance) without which meaningful interpretation of the data is not possible.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaOf special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof root, flower and leaf microbiomes in the wild strawberry plant

Methodology challenges in studying human gut microbiota — effects of collection, storage, DNA extraction and next generation sequencing technologies — Marina Panek — Scientific Reports

In a study published as a letter to the journal Gut, the team outline new evidence suggesting that the human genome may play a role in determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbioGut, the team outline new evidence suggesting that the human genome may play a role in determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbiogut microbiota.

At Weizmann, she plans to investigate the impact of gut microbiota on aging, and her goal is to improve human health through personalized nutrition.

Techniques Functional imaging of the interaction between gut microbiota and the human host: A proof - of - concept clinical study evaluating novel use for 18F - FDG PET - CT.

Human gut microbiome ** Competitively Selected Donor Fecal Microbiota Transplantation: Butyrate Concentration and Diversity as Measures of Donor Quality.

Multi-site human microbiome Review: The Vagus Nerve at the Interface of the Microbiota - Gut - Brain Axis.

Spurred by this finding, Littman's team examined the gut microbiota in patients with rheumatoid arthritis, a debilitating autoimmune disease, and found a much higher proportion of patients than healthy individuals who harbored the human intestinal bacterium Prevotella copri.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

* Potential and active functions in the gut microbiota of a healthy human cohort — Alessandro Tanca — Microbiome

Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota — Carolina Serena — The ISME Journal

Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis — Jocelyn Sietsma Penington — Scientific Reports

The human gut harbors a complex community of microbes, collectively called microbiota.

This specialist knowledge has been crucial to thoroughly mine the human gut microbiota, particularly in the absence of methods for the routine cultivation of most enteric microorganisms.

These observations support the hypothesis of functional redundancy in the human gut microbiota.

To do this, they colonized the intestines of germ - free mice with a synthetic human gut microbiota and exposed the mice to either a plant fiber - free diet or a plant fiber - rich diet.

How do the microbes within cheese interact with the natural microbiota of the human gut and can cheese be used to assist in maintaining a healthy gut microbiota?

Cellular and Molecular Life Sciences (2017): 1 - 19; Wiley, N. C., et al. «The microbiota - gut - brain axis as a key regulator of neural function and the stress response: Implications for human and animal health.»

The great news is that by adding fermented veggies into your foods, you are changing your gut health for better: «the composition of the gut microbiota has been shown to differ in lean and obese humans and animals and to change rapidly in response to dietary factors.

Hence, a lot of necessary neurotransmitters in the body are generated by the gut microbiota, exerting influence on the human body including the brain, among which many neurotransmitters in the human gut microbiota are also critical molecules.»

Known in the past as gut bacteria and gut flora, the microbiota, or microbiome, is a collection of about 1,000 different kinds of bacteria that have immense importance to human health.

The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.

Effects of a gluten - free diet on gut microbiota and immune function in healthy adult human subjects.

The closest I've found to a human clinical trial of beans on intestinal permeability is this study, which found a Chinese medicinal gruel of Job's tears, oat, buckwheat, white bean, yellow corn, red bean, soybean, yam, big jujube, peanut, lotus seed, and wolfberry changed gut microbiota, improved gut permeability, lowered endotoxemia, and improved inflammation markers.

Role of the gut microbiota in defining human health.

Sources: Clemente, J.C., et al., «The Impact of the Gut Microbiota on Human Health: An Integrative View,» Cell 2012; 148 (6): 1258 - 1270.

Fecal Transplant FMT, also known as fecal microbiota transplant, human probiotic infusion, bacteriotherapy, and fecal transplant, is a powerful infusion of healthy colon flora treatment which has been used to treat c diff, aka C difficile infections, inflammatory bowel disease, irritable bowel syndrome, autoimmune disease, dysbiotic gut flora as well as other conditions.