Sentences with phrase «of human kidney»

In the later stages of human kidney disease, when some physicians believe that truly low protein diets are advisable, some physicians and nutritionists attempt to get around the dangers of low protein by supplementing the patient's diet with amino acids that have been enzymatically oxidized into keto (C =O) amino acids.

Here, we describe a microfluidic device lined by living human kidney epithelial cells exposed to fluidic flow that mimics key functions of the human kidney proximal tubule.

Immunohistochemistry - Paraffin: Emx1 Antibody - Staining of human kidney shows moderate nuclear positivity in cells in a subset of renal tubules.

As a result of these findings, the team were able to conclude that the Drosophila model was an effective and accurate model of human kidney disease.

The test drug slowed the growth of kidney cysts in two mouse models and in cell cultures of human kidney cysts, the study showed.

Salk Institute scientists have discovered the holy grail of endless youthfulness — at least when it comes to one type of human kidney precursor cell.

The data bring an understanding of human kidney development to a new level,» said Dr. McMahon.

An ear scaffold, left, provides the structure to grow human cells.A kidney stripped of cells, right, awaits an injection of human kidney cells, part of the process of engineering a new organ.

To date, the researchers have tested the function of their activation - ready sensor in cell culture of human kidney and cancer cells.

Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of human kidney development and toxicity.

Not exact matches

While mindful of the negative connotations that might arise from manufacturing body parts and implanting them, cyborg style, in humans, he doubts someone on a waiting list for a new kidney and requiring daily dialysis would have such qualms.

I would like to repeat, the brain is just like any other organ and just as capable of failing as a human heart, a kidney or a lung.

But the liver also, the kidneys, and the bowels were for them important centers of human consciousness and volition.

its never a «potential» human as many of you say... a kidney is a bodily organ and nothing more... thus to compare it to a fetus is idiocy and a desperation to try to justify killing the unborn

She held previous positions at Grocery Manufacturers Association (GMA), Human Genome Sciences, Inc. and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

A lot of nutrients are lost to pasteurization and again when the milk is watered down (it has to be watered down or the high levels of protein would damage the kidneys) and some nutrients that humans need were never there in the first place.

This is because the liver locates on the right side of the human body; sleeping on the left side will make sure that the pressure of the growing uterus will not be applied directly onto the liver, thereby improving the circulation of the heart and to the uterus, fetus, and kidneys as well.

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

The Golden Goose Award has honored innovative research that developed a diabetes medication from Gila monster venom, an algorithm based on marriage stability that led to the development of a program to match kidney patients with donors and the «marshmallow test» — a measure of young children's self - control that has led to greater understanding of human behavior.

The team has already successfully repopulated pig kidneys with human cells, but Ott says further studies are vital to guarantee that the pig components of the organ do not cause rejection when transplanted into humans.

Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293 cells was dependent on added Wnt5A protein and was accomplished by the multifunctional adaptor protein β - arrestin 2 (βarr2), which was recruited to Fz4 by binding to phosphorylated Dvl2.

The team is now attempting the same procedure using human kidneys, and also pig kidneys, which could be used to make scaffolds if there were a scarcity of human donors.

«If this technology can be scaled to human - size grafts, patients suffering from renal failure, who are currently waiting for donor kidneys, could theoretically receive an organ grown on demand,» says Harald Ott, head of the team that developed the rat kidneys at the Massachusetts General Hospital in Boston.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

We showed that a one - time dose of the drug mirabegron stimulates human brown adipose tissue so that it consumes glucose and burns calories,» said lead author Dr. Aaron Cypess, who conducted the work at Joslin Diabetes Center and Beth Israel Deaconess Medical Center, affiliates of Harvard Medical School, and is now at the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

That is because «the human kidney is made, by design, to vary the accretion of salt based on the amount you take in,» explains Michael Alderman, an epidemiologist at the Albert Einstein College of Medicine and former president of the International Society of Hypertension.

«Just like the human brain, heart and kidneys — organs that can commandeer heightened blood flow when needed — the placenta may employ an auto - regulatory mechanism to optimize perfusion,» adds Limperopoulos, director of Children's Developing Brain Research Laboratory and the study's senior author.

In 2008, when he fed Lactobacillus to mice with a transplanted human microbiome, he observed metabolic changes in the animals» gut, liver, kidneys, and parts of the brain.

If she has her way, animal farms will raise herds of bioengineered pigs, designed to produce kidneys, livers and other organs that could be transplanted into humans.

As of July 22, 2015, 101,144 patients are currently waiting for kidney transplants, according to the U.S. Department of Health and Human Services.

Tengion develops human «neotissues and neoorgans» using their Autologous Organ Regeneration Platform, and currently has several ongoing preclinical and clinical trials in the area of bladder and kidney augmentation and blood vessel replacement.

Tests with kidney cancer and two human uterine sarcoma cell lines, one with multidrug resistance, showed that 10 of these new compounds were impressively potent against all three cell lines, the researchers reported.

Normal human colon cells, kidney cells, lung cancer cells and two strains of colon cancer cells didn't respond to the bacteria.

«Just one transplant of the human EPO - producing cells treated kidney anaemia in mice, keeping their haemoglobin levels in the normal range for the remaining 7 - month lifespan of the animals,» says Kenji Osafune, of Kyoto University in Japan, who led the team.

Human kidneys filter atrazine, and humans don't spend a lot of time swimming in pesticide - laced water, the way frogs do.

Greg Fahy of the American Red Cross in Bethesda, Maryland, said last week that he and his colleagues hope to have developed a method for preserving rabbit kidneys — which are very similar in tissue type and structure to human ones — by Christmas.

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.

In the study conducted in collaboration with the Buck Institute on Aging and the Children's Hospital of Oakland Research Institute, scientists decided to look within humans and the flies (MADE THIS PLURAL) to explore the interplay of zinc with oxalate, calcium and other minerals that make up kidney stones.

After running the simulations at IU Bloomington, Bacallao confirmed the cyst growth predictions seen in the virtual cysts in experiments using real human cells cultivated from polycystic kidneys from patients at the IU School of Medicine.

A search of the CRISP database of NIH - funded research projects on three key words — mutant, androgen, and receptor — yields 24 projects funded since 1999 by nine different NIH institutes: the National Cancer Institute (eight projects), the National Institute of General Medical Sciences (NIGMS, three projects), the National Institute of Child Health and Human Development (three projects), the National Institute of Diabetes and Digestive and Kidney Diseases (two projects), and the National Center for Research Resources (two projects).

His current research portfolio focuses on the investigation of novel approaches for the regenerative medicine of the kidney, including the study and characterization of human nephrogenic progenitors and the investigation of approaches for the treatment of Alport syndrome and other chronic kidney diseases.

Here, 8th - to - 12th - graders plop together the varied pieces of human anatomy, from the cerebellum down to the kidneys.

The human kidney cell involved survived the experience, and though we are a long way from the laser eyes of Cyclops from the X-Men franchise, the achievement suggests that «living lasers» might be created inside live animals.

Derived mostly from human embryonic kidney 293T (HEK293T) and HeLa cell lines, EdiGene Knockout (KO) Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gene.

A cross-campus group of faculty and staff from the University of Michigan's Department of Human Genetics, Department of Epidemiology, Kidney Epidemiology and Cost Center, Center for Statistical Genetics, Department of Biostatics, Department of Internal Medicine, Department of Computational Medicine and Bioinformatics and the Institute for Social Research contributed to the papers.

They also hope to use what they learn from simple models of different tissue types to ultimately build functional human tissues like lung and kidney and neural circuits using larger - scale techniques.

In previous studies, including recent genome sequencing of cancer patients, human SETD2 has been implicated in several cancer types, especially in renal cell carcinoma — the most common kind of kidney cancer.

To determine if increasing the level of NAD would accelerate recovery from kidney injury, the researchers administered extremely large quantities of vitamin B3 nutritional supplements — the human equivalent of hundreds of tablets - to the genetically impaired mice.

So we tested this in mouse models and in human polycystic kidney tissues, and, in both cases, high levels of pIgR were expressed in kidney cysts.»

Now that they have a FAN1 knockout mouse in hand, and they have confirmed that it mimics many aspects of karyomegalic interstitial nephritis in humans, Smogorzewska's lab can start to delve into how the loss of the gene causes kidney degeneration.