Sentences with phrase «of human leukemia»

FeLV (Feline Leukemia Virus) and FIV (Feline Immunodeficiency Virus) are both in the retrovirus category, the same type of virus responsible for HIV and some forms of human leukemia.

Phytates have been shown to inhibit the growth of human leukemia cells, colon cancer cells, both estrogen receptor - positive and negative breast cancer cells, voicebox cancer, cervical cancer, prostate cancer, liver tumors, pancreatic, melanoma, and muscle cancers.

Vitamin K2 induces certain kinds of human leukemia cells to differentiate, or turn into normal white blood cells.

Lapotko D, Lukianova E, Оraevsky A. Selective laser nano - thermolysis of human leukemia cells with microbubbles generated around clusters of gold nanoparticles.

Gallo and his colleagues then opened and pioneered the field of human retrovirology with the discovery of the first human retrovirus (HTLV - 1) and along with Japanese investigators showed it was a cause of a particular form of human leukemia.

Its first target was the regulatory network involved in controlling the differentiation of THP - 1 cells, a line of human leukemia cells used in laboratory experiments.

The researchers were able to identify the new molecular targets by conducting a global proteomic analysis of human leukemia cells.

The study involved laboratory cell lines of human leukemia and mouse models of the disease.

Not exact matches

Some of these risks include the presence of cytomegalovirus (CMV), hepatitis, human immunodeficiency virus (HIV), human T - cell leukemia virus type 1 (HTLV - 1) or other viruses on the pump parts that were exposed to the previous mother's breastmilk.

Some of the viruses that can be within breast milk are: HIV — Human Immunodeficiency Virus (AIDS) HTLV - 1 Human T - Cell Leukemia Virus Type I CMV — Cytomegalovirus When you are using a previously owned breast pump you create the risk of cross contamination.

Also, women with human T - cell leukemia virus type 1 (HTLV - 1) should not breastfeed because of the risk of transmission to the child.

For the infant, human milk reduces the rates of infection, allergies, obesity, diabetes, leukemia, lymphoma, SIDS, and infant mortality2.

According to U.S. Department of Health and Human Services (HHS), breast milk can lead to a lower risk of asthma, childhood leukemia, obesity, ear infections, sudden infant death syndrome (SIDS) and respiratory infections.

That's how Charles Sawyers, a 2009 Lasker Award winner and chair of human oncology and pathogenesis at Memorial Sloan - Kettering Cancer Center in New York City, made the connection with Bristol Myers Squibb (BMS) that led to second - generation treatments for chronic myeloid leukemia (CML).

Gene therapy procedures in humans have been linked to the onset of leukemia and various tumors, as well as sudden death.

In another the therapy worked, but 4 of the 10 human subjects — young children — got leukemia.

The researchers have shown that it is possible to produce chromosome modifications in human cells that are genetically identical to those observed in leukemia and other types of human cancer.

By promoting DNA demethylation, high - dose vitamin C treatment induced stem cells to mature, and also suppressed the growth of leukemia cancer stem cells from human patients implanted in mice.

«The bacterial enzyme killed about 90 % of the MOLT4 human leukemia cells and displayed low toxicity to the healthy HUVEC cells, killing only 10 %,» Monteiro said.

«Our partnership with families who have a child with Down syndrome and our investment in a comprehensive clinical data and biorepository will continue to provide resources to study not only heart defects, but also other Down - syndrome associated medical conditions such as cognitive function, leukemia, and dementia,» says co-author Stephanie Sherman, PhD, professor of human genetics at Emory University School of Medicine.

Coffin and his collaborator, Vinay Pathak, suggested that with each passage, the human cells acquired genetic portions of a murine leukemia virus, which then merged to form a new virus — a hybrid of the parent sequences.

MLVs so dependably cause cancer in lab - bred mice — especially leukemia and lymphoma — that a small fraternity of scientists at the NCI and elsewhere has fruitfully studied these viruses since the 1960s in an effort to understand how human cancer begins.

In another the therapy worked, but 2 of the 10 human subjects — infants — got leukemia.

As a result of the finding, researchers can also use Mauritian cynomolgus macaques to improve stem cell transplant outcomes for human patients with other blood - related conditions such as leukemia and sickle - cell disease.

Scientists of the Senckenberg Center for Human Evolution and Paleoenvironment and the University of Tübingen have discovered what may well be the oldest known case of Leukemia.

In an extensive sleuthing expedition that looked back nearly 20 years, two collaborating research teams contend that they have evidence that xenotropic murine leukemia virus — related virus (XMRV) resulted from the chance recombination of pieces of two mouse viruses in lab experiments and that the connections to human disease are spurious.

Research carried out at the Division of Genetics at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) with support from the Institute for Human Genetics has now discovered another molecular cause for a particularly aggressive type of leukemia in infants.

A year later, Carlo Croce, now director of the Human Cancer Genetics Program at Ohio State University, reported that chronic lymphocytic leukemia (CLL), the most common form of the disease, was caused by deletion of two microRNA genes.

One, the simian immunodeficiency virus, is the predecessor of HIV; the other is simian T - lymphotropic virus 1, whose descendant in humans, HTLV - 1, can cause leukemia.

Their preliminary findings indicate that MUS81 - induced movement of DNA to the cytosol also occurs in human cancer cells, including prostate cancer, breast cancer, colorectal cancer, uterine cancer, leukemia, and melanoma cells.

This work is supported by the Leukemia & Lymphoma Society, the Human Frontiers Science Foundation, the NIH / National Institute of General Medical Sciences (GM088313), the American Cancer Society (121776), and the Human Frontiers Science Program.

When tested in laboratory samples of leukemia cells and in animals with human - like leukemia, the approach caused cancer cells to die much more quickly than with conventional targeted therapies.

Beilhack and colleagues found that a slightly modified version of STAR2 has a similar effect on human T reg cells, suggesting that the approach could also prevent GvHD in leukemia and lymphoma patients after bone marrow or hematopoietic stem cell transplants.

The human genome contains around 20,000 genes, by refining CRISPR - Cas9 technology and using it to screen the leukemia genome the team uncovered a catalogue of approximately 500 genes that are essential for cancer cell survival, including more than 200 genes for which drugs could be designed.

Grossman, WJ, Kimata, JT, Wong, FH, Zutter, MM, Ley, T, Ratner, L. Development of leukemia in mice transgenic for the Tax gene of human T - cell leukemia virus Type 1.

«Remissions of Acute Myeloid Leukemia and Blastic Plasmacytoid Dendritic Cell Neoplasm Following Treatment with CD123 - Specific CAR T Cells: A First - in - Human Clinical Trial» is presented at the ASH Annual Meeting Dec. 9 to 12, 2017.

Locafaro G *, Andolfi G *, Russo F, Camisa B, Ciceri F, Bondanza A, Roncarolo MG *, Gregori S. HLA class I - dependent targeting of myeloid leukemia by IL -10-engineered human CD4 + Tr1 cells.

Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.

The granted projects focus on several human diseases including leukemia and Alzheimer's disease as well as the study of biodiversity of organisms as diverse as barnacles, mycorrhiza and rabbits.

Interestingly, runx1 is also one of the most frequently mutated genes in human leukemias, supporting that runx1 plays an important role in the adult.

Human T - cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation.

Secretion of the human T cell leukemia virus type I transactivator protein tax.

Identification of human T cell leukemia virus type 1 tax amino acid signals and cellular factors involved in secretion of the viral oncoprotein.

Induction of Differentiation and Cellular Manipulation of Human Myeloid HL - 60 Leukemia Cells.

This work raises the possibility that histones can signal to non-histone proteins in human cells, and that deregulation of these events caused by MLL mutations might contribute to leukemia development.

St. Jude researchers working with collaborators in China and Singapore have reported evidence that mutations in non-coding regions of the human genome contribute to leukemia in children and may offer promising targets for treatment in the future.

ABL tyrosine kinases play an oncogenic role in human leukemias (4, 5) and promote the progression of solid tumors (5, 6).

The lab chose to use the TCL1 mouse model to study B - cell leukemia because ~ 90 percent of human chronic lymphocytic leukemia (CLL) patients express the TCL1 protein, and the overexpression of TCL1 in B cells leads to the development of CLL in mice.

He notes that students are involved in every step of the research process — growing human leukemia cells, performing the experiments, analyzing the data that the experiments generate and interpreting those data as to what they're saying about the cells» genetic network.

The lab further developed inhibitors to target the expression of XBP - 1 and established that blocking the expression of XBP - 1 by specific small - molecule chemical inhibitors can stall malignant progression of leukemia in mice and induce apoptosis in primary human leukemic cells.