Effects of Storage Duration and Temperature
of Human Plasma and Serum on Red Blood Cell Aggregation and Shape
Albumin normally constitutes about 60 %
of human plasma protein and plays an important role in regulating blood volume by maintaining the oncoosmotic pressure of blood needed to avoid edema, and by serving as the carrier for hydrophobic molecules, including lipid soluble hormones, bile salts, unconjugated bilirubin, free fatty acids (apoprotein), calcium, ions (transferrin), and some drugs (e.g., warfarin, phenobutazone, clofibrate & phenytoin).
Transcriptional control
of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon - alpha
Multi-component immunoaffinity subtraction chromatography: an innovative step towards a comprehensive survey
of the human plasma proteome.
For example, Thermo Fisher Scientific's HRAM Orbitrap - based MS systems can detect as many as 1,000 metabolites from several microliters
of human plasma in less than an hour.
Not exact matches
Now, none
of these should be confused with coconut water, which is the fluid inside coconuts — which, interestingly, is so close in composition to
human plasma that in an emergency, you can use coconut water intravenously.
Human plasma carotenoid response to the ingestion
of controlled diets high in fruits and vegetables
The effects
of fat and protein on glycemic responses in nondiabetic
humans vary with waist circumference, fasting
plasma insulin, and dietary fiber intake
Plasma, erythrocyte
human milk levels
of free amino acids in lactating women administered aspartame or lactose.
Concentrations
of N - descyclopropylmethylprazepam in whole - blood,
plasma, and milk after administration
of prazepam to
humans.
This means alcohol transfers into
human milk with an average milk /
plasma ratio
of one.
Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays
of functional
human proteins (over 20,000 on a single array) to test the antibodies present in
human liquid biopsy samples, such as blood, serum,
plasma, CSF, or tissue lysates.
It interacts with a
human plasma - membrane lipid, phosphatidylserine, to facilitate replication
of the virus.
«This recombinant method has a good shot at making HSA more abundantly and more safely than
human plasma, and it will at least have a shot at being as cost - effective,» says William Velander, an expert in genetically engineered therapeutics at the University
of Nebraska - Lincoln.
«Starting with our cell model that mimics
human pancreatic cancer progression, we identified released proteins, then tested and validated a subset
of these proteins as potential
plasma biomarkers
of this cancer,» Zaret said.
Joseph Castellano at Stanford University in California and his colleagues discovered this by collecting blood from people at three different life stages — babies, young people around the age
of 22, and older people around the age
of 66 — and injecting the
plasma component into mice that were the equivalent
of around 50 years old in
human years.
A trial is under way at a hospital in South Korea to test whether injections
of human umbilical cord
plasma have anti-ageing effects in healthy people aged 55 or older.
«Direct and regular observation
of plasma by satellites started after the late 1960s — almost a decade after the first
human - made satellite, Sputnik 1, was launched in 1957,» explains Masahito Nosé, an author
of the study.
-- Hyperimmune globulin, prepared by purifying and concentrating
plasma of immunized animals or previously infected
humans with high titers (concentrations)
of neutralizing antibody against Ebola virus, which have been shown to be protective in monkeys but are not currently available and would not be expected before mid-2015.
Researchers have previously found that blood from
human teenagers can rejuvenate memory and cognition in elderly mice, probably due to factors present in the
plasma — the liquid portion
of the blood.
They gave aging mice (engineered to have deficient immune systems that would not adversely react to
human plasma) infusions
of the three types
of plasma every fourth day for two weeks.
Since cold
plasma has not been used on
human beings before, the top priority
of the Fraunhofer IST was to evaluate the safety
of the solution.
These reference standards consist
of human genomic DNA fragmented to 160 base pairs, representative
of plasma - derived cfDNA, and are provided as a set
of precisely defined allelic frequencies from as low as 0.1 %.
On the basis
of those results, at least one company is attempting to replicate the effect in
humans using blood
plasma from healthy young people to treat patients with Alzheimer's disease.
At any given moment, the
human body excretes thousands
of metabolites that can be measured in urine,
plasma and various body tissues.
In normal subjects, hypoglycemia produces an abrupt and sustained rise in levels
of human growth hormone in
plasma.
A new study, published online May 26 in Science Translational Medicine, presents a thorough profile
of exercise's impact on the
human body's metabolites in
plasma — and reveals vast biological differences among more - and less - fit individuals.
When Yousef injected
plasma from people in their late 60s into the bodies
of 3 - month - old mice — about 20 years old in
human terms — the mice's brains showed signs
of ageing.
Cardiovascular effects
of methylphenidate in
humans are associated with increases
of dopamine in brain and
of epinephrine in
plasma
Protein expression profiles
of human lymph and
plasma mapped by 2D - DIGE and 1D SDS - PAGE coupled with nanoLC - ESI - MS / MS bottom - up proteomics.
A group
of NUST MISIS's young scientists has presented a new therapeutic material based on nanofibers made
of polycaprolactone modified with a thin - film antibacterial composition and
plasma components
of human blood.
Most patients with immune deficiency are treated with
plasma - based drug products derived from
plasma samples that are pooled from thousands
of human donors.
N - acetylcysteine reduces the size and activity
of von Willebrand factor in
human plasma and mice.
Dosing
of mebendazole
of 30 - 87 mg / kg / day in
humans resulted in
plasma levels
of 120 -218 nM (260 nM for continuous administration) with coefficients
of variation ranging from 27 to 72 %.
Anaplastic, plasmablastic, and plasmacytic plasmacytomas
of mice: relationships to
human plasma cell neoplasms and late - stage differentiation
of normal B cells.
«Both the neuronal and average
human membrane models — arguably the most compositionally complex
plasma membrane lipid models to date — showed non-ideal lateral lipid mixing at different length and time scales, demonstrating the inherent complexity
of biological membranes.»
A growing number
of human studies suggest that a low
plasma Aβ42 / Aβ40 ratio is a risk factor for major depression, 45, 46 dementia47 and higher mortality.48 The Framingham Study also showed that increased
plasma Aβ42: Aβ40 ratios are associated with decreased risk
of AD and dementia.13 Thus, the higher Aβ42 / Aβ40 ratio observed in regular meditators at baseline and the increase in this ratio from pre - to post intervention in the novice meditator and vacation groups may be salutary to brain health.
Western blot analysis
of antibody specificity has been done using a routine sample setup composed
of IgG / HSA - depleted
human plasma and protein lysates from a limited number
of human tissues and cell lines.
Background: Studies conducted in animal models and
humans suggest the presence
of a dynamic equilibrium
of amyloid - β (Aβ) peptide between cerebrospinal fluid (CSF) and
plasma compartments.
Abstract: Background: Studies conducted in animal models and
humans suggest the presence
of a dynamic equilibrium
of amyloid - β (Aβ) peptide between cerebrospinal fluid (CSF) and
plasma compartments.
Similarly, inactivating mutations affecting the expression
of APOC3 in
humans led to reduced
plasma TG levels (8) and protection against CVD (9 — 11).
Finally, this study demonstrated that provoked hypothesis driven physiological studies in
human knockouts should discover new biology; for instance, after challenge with oral fat, APOC3 knockouts displayed marked blunting
of the usual post-prandial rise in
plasma triglycerides compared to wild - type family members.
Modality
of access under this proposal: Users can provide
human or animal serum,
plasma or tissue samples, or cell pellets or supernatants from cell models.
Elevated
plasma TG levels represent a risk factor for CVD in
humans, and an adjusted analysis
of patients in the Framingham Heart Study suggests that each decrease
of 1 mg / dl in
plasma ApoC - III levels is associated with a 4 % decrease in CVD risk (11), further supporting the potential therapeutic benefit
of suppressing
plasma ApoC - III levels in
humans to reduce CVD.
Some
of the research covered in the documentary includes scientists who are identifying and characterizing planets orbiting other stars (the other planets in our solar system would likely be more trouble than they're worth to make comfortable, the film argues); an engineer building a rocket fueled by
plasma, the same charged particles found in our sun; and a team building a fleet
of robots that could construct habitats before
humans even arrive at their destination.
The levels
of ciprofloxacin in surface water around the Indian plant exceeded
human therapeutic blood
plasma concentrations, and were thus presumably toxic for a wide range
of bacteria.
To measure total lipase activity,
plasma samples were incubated with 10 % Intralipid / [3H] TG emulsion (Hospira) as a substrate and
human serum as the source
of ApoC - III (24).
A California - based startup that provides transfusions
of human blood
plasma from young people to older people claims that results from its
human trial show improvements in biomarkers related to Alzheimer's, cancer, and heart disease.
A pool
of normal
human plasma was used as a negative control (NC).
Antiviral effects
of plasma and milk proteins: lactoferrin shows potent activity against both
human immunodeficiency virus and
human cytomegalovirus replication in vitro.