Sentences with phrase «of human serum»

Characterization of Human Serum Albumin - Facilitated Lipofection Gene Delivery Strategy.

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency, in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi.

In case of human sera special requirements may apply.

Not exact matches

Some people believe that the President of the United States is actually an alien that has taken human form and that the flu shots are mind control serum.

Human studies have even shown antibodies to wheat germ agglutinin in the serum of healthy individuals.

(See: The Potential Health Benefits Of Makapuno Coconut Byproduct) Previous studies done on coconut flakes and coconut flour have also shown that the dietary fiber of coconut can reduce cholesterol levels (e.g. see: The Cholesterol - Lowering Effect of Coconut Flakes in Humans with Moderately Raised Serum CholesteroOf Makapuno Coconut Byproduct) Previous studies done on coconut flakes and coconut flour have also shown that the dietary fiber of coconut can reduce cholesterol levels (e.g. see: The Cholesterol - Lowering Effect of Coconut Flakes in Humans with Moderately Raised Serum Cholesteroof coconut can reduce cholesterol levels (e.g. see: The Cholesterol - Lowering Effect of Coconut Flakes in Humans with Moderately Raised Serum Cholesteroof Coconut Flakes in Humans with Moderately Raised Serum Cholesterol)

Although most of these biosubstances have been identified in mother's milk in quantities that exceed maternal serum levels, their exact role in human newborns is uncertain; most current information is from animal models whose development may significantly differ.

Spironolactone: relationship between concentrations of dethioacetylated metabolite in human serum milk.

Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays of functional human proteins (over 20,000 on a single array) to test the antibodies present in human liquid biopsy samples, such as blood, serum, plasma, CSF, or tissue lysates.

«We also anticipate that the use of this method will be able to evaluate human serum samples to identify spectral signatures that can distinguish between Crohn's disease and ulcerative colitis.»

«From many candidates, we chose one that is both easily distinguished from human serum proteins and an unambiguous indicator of the bacteria,» Turko says.

These findings call into question the safety of the recent substitution of DiNP for DEHP in soft PVC, particularly since a shorter male AGD has been shown to be related to male genital birth defects in children (such as hypospadias and undescended testis) and impaired reproductive function in adult males (such as decreased fertility, impaired semen quality and lower serum testosterone levels) and the fact that human levels of DiNP are rapidly increasing globally, says Carl - Gustaf Bornehag, professor in Public Health Sciences at Karlstad University and responsible for the current study.

This differential response depends on a «natural» immune response environment, that is, on the presence of human blood serum.

Now, researchers from the Department of Chemistry at Imperial College London have come up with a system that is specific, flexible, and can detect single protein biomarkers directly in human serum (a pool of fluid separated from blood).

It was discovered that adiposity is transmissible from human to mouse and that it was associated with changes in serum levels of branched - chain amino acids.

After collecting biopsies from banked human donor eyes, the team expanded the numbers of cells in a culture plate using human serum to nourish them.

University of Alabama at Birmingham researchers have found that amounts of this microRNA are significantly elevated in the brains of experimental rats with induced depression from corticosterone treatment, in the post-death brains of humans diagnosed with MDD and in peripheral blood serum from living patients with MDD, according to a study by led by Yogesh Dwivedi, Ph.D., the Elesabeth Ridgely Shook Endowed Professor and director of Translational Research, UAB Mood Disorders Program, Department of Psychiatry.

Vaccines made from the brains of infected animals protect humans and animals, but the serum can contain impurities which cause encephalitis — a dangerous inflammation of the brain.

In animals harboring intraperitoneal hollow - fiber or subcutaneous implants containing light - inducible transgenic cells, the serum levels of the human glycoprotein secreted alkaline phosphatase could be remote - controlled with fiber optics or transdermally regulated through direct illumination.

The researchers found that resistin, an immune protein commonly found in human serum, instigates an inappropriate inflammatory response to worm infections, impairing the clearance of the worm.

Wet skin isn't the only challenge for medical adhesives — the human body is full of blood, serum, and other fluids that complicate the repair of numerous internal injuries.

Based on the observation that obese mice, rats, and humans all had elevated serum concentrations of a protein called GDF15 compared to lean controls, Yumei Xiong and colleagues set out to develop therapies derived from the molecule.

To assess cross-neutralization of TMAdV by known human adenoviruses, 7 pools of in - house reference sera at the VRDL (rabbit hyperimmune sera) and collectively containing antibodies to human adenovirus serotypes 1 through 35 were available for testing.

To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV - 1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has previously been reported in llamas.

To explore a potential link between the outbreak and associated illness in humans, we blindly tested available sera from titi monkeys (n = 59), rhesus macaques housed in the same building (n = 36), CNPRC personnel and close contacts (n = 20), and random human blood donors (n = 81) for evidence of recent or prior infection by TMAdV by virus neutralization (Fig. 6).

For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respectively.

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have discovered a peripheral biomarker in human blood serum that can be used to detect the presence and progress of glioblastoma brain tumors before and after treatment.

GC - MS Based Metabolomics and NMR Spectroscopy Investigation of Food Intake Biomarkers for Milk and Cheese in Serum of Healthy Humans — Alessia Trimigno — Metabolites

In collaboration with Dr. Josh Thaden and Vance Fowler, Duke University Medical Center, we are exploring relationships between bacterial genetic variation, emergence of AMR, and patient outcome in Enterobacter and Escherichia coli Bloodstream Infections (BSI) by leveraging the Duke University Bloodstream Infection Biorepository (BSIB), which contains robust clinical data, bacterial bloodstream isolates, and corresponding human sera and DNA from over 2000 patients with BSI caused by Gram - negative bacteria at Duke Hospital since 2002.

Inclusion Criteria: • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 • Have histologically or cytologically confirmed advanced or metastatic non-small cell lung cancer (NSCLC)(Stage IIIb or greater) • Measurable disease, as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 • Known PD - L1 tumor status as determined by an immunohistochemistry (IHC) assay performed by the central laboratory on tissue obtained at Screening • A woman of childbearing potential must have a negative highly sensitive serum (beta - human chorionic gonadotropin [beta - hCG]-RRB- at Screening within 14 days prior to study drug administration Inclusion Criteria for Crossover: • Participants must have been randomized to Arm A of the study and had radiographic disease progression according to RECIST 1.1 • Participants must have a mandatory biopsy at the time of disease progression according to RECIST 1.1 prior to crossing over.

This protein binds to murine monoclonal antibodies of defined epitope specificity and HIV - 1 converted human serum polyclonal antibodies in ELISA and Western

Human volunteers given an oral dose of 2 g niclosamide exhibited maximal serum concentration of 0.25 - 6 μg / ml and eliminated the drug within 2 days.

This protein binds to murine monoclonal antibodies of defined epitope specificity and human serum polyclonal antibodies in ELISA and Western ELISA.

Lack of cross-reactivity between the Bacillus thuringiensis derived protein Cry1F in maize grain and dust mite Der p 7 protein with human sera positive for Der p 7 - IgE.

StemSpan ™ SFEM II Serum - Free Expansion Medium Containing CD34 + Expansion Supplement Supports Greater Expansion of Human CD34 + Cells Than Other Media Tested

Dr. Bovenkamp conducted further research at the Johns Hopkins University Bayview Proteomics Center in the Division of Cardiology at Johns Hopkins School of Medicine in Baltimore, Maryland, using proteomic techniques for biomarker detection in human serum.

Immunoblot analysis using mouse monoclonal antibody to human IgM detected IgM to cytomegalovirus (CMV)- specific proteins (150, 42, 38, 32, and 28 kDa) in 74 (38 %) of 197 seropositive serum samples from 197 individuals in three subject groups: 43 surgical patients, 31 patients with solid tumors, and 123 healthy individuals.

The IgMs accounted for essentially all of the misTTR hydrolytic activity of unfractionated human serum.

Liquid chromatography - mass spectrometry - based parallel metabolic profiling of human and mouse serum reveals putative biomarkers with the progression of nonalcoholic fatty liver diseases.

What is perhaps most notable in the study by Liu et al (36) was that human monocytes, in human serum, exhibited biologically important differences in microbicidal response within the range of serum 25 (OH) D values commonly found in free - living populations.

Reykjavik, ICELAND, 9 October 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, Norway, Denmark, the Netherlands and the USA today report the discovery of low frequency variants in the human genome that associate with risk of gout, a common inflammatory arthritis, and serum uric acid levels.

Modality of access under this proposal: Users can provide human or animal serum, plasma or tissue samples, or cell pellets or supernatants from cell models.

Hu C et al. (2015) Autoantibody Profiling on Human Proteome Microarray for Biomarker Discovery in Cerebrospinal Fluid and Sera of Neuropsychiatric Lupus.

Human pulmonary artery endothelial cells cultured with serum from homozygous carriers showed an increase in MCP - 1 release in carriers of the minor allele, with the difference eliminated upon addition of tocilizumab.

To measure total lipase activity, plasma samples were incubated with 10 % Intralipid / [3H] TG emulsion (Hospira) as a substrate and human serum as the source of ApoC - III (24).

The CDI HuProt microarray contains nearly 75 % of the human proteome on a single glass slide, a unique and powerful tool for high - throughput serum profiling and biomarker discovery.

Like Neu5Gc, they found that human cells and serum have only trace amounts of Gc - CS — again, likely from red meat consumption.

Dr. Herta Spencer, of the Veterans Administration Hospital in Hines, Illinois, explains that the animal and human studies that correlated calcium loss with high protein diets used isolated, fractionated amino acids from milk or eggs.19 Her studies show that when protein is given as meat, subjects do not show any increase in calcium excreted, or any significant change in serum calcium, even over a long period.20 Other investigators found that a high - protein intake increased calcium absorption when dietary calcium was adequate or high, but not when calcium intake was a low 500 mg per day.21

Aldosterone reverses certain types of hearing loss inn experimental animals100, 101, 102, 103, and levels of serum aldosterone have been inversely correlated with degree of hearing in humans.104 Case studies at Tahoma Clinic, Renton, Washington, have found that a significant percentage of individuals with hearing loss and low levels of aldosterone recover some of their hearing when exogenous aldosterone is taken.105

Quantitative measurement of endogenous estrogens and estrogen metabolites in human serum * by liquid chromatography - tandem mass spectrometry.