Sentences with phrase «of hyperalgesia»

Colvin says she already sees strong evidence of hyperalgesia in high - dose opioid users at the clinic where she works.

Surgical patients given large amounts of the opioid remifentanil have shown signs of hyperalgesia; they have larger areas of soreness around their wounds and seem predisposed to chronic pain following surgery.

After the drug treatment, the team found signs of hyperalgesia: On average, the subjects registered pain from the ice water about 2 seconds earlier, and removed their hands about 8 seconds earlier, than they had beforehand.

He believes the risk of hyperalgesia should motivate doctors to try tapering patients off their opioids when their pain worsens without an obvious cause.

A research team in Israel reported evidence of hyperalgesia in 17 of 30 patients with radiating spinal nerve pain by asking them to rate the intensity of heat pain on a numerical scale before and after a 4 - week course of hydromorphone.

Hutchinson thinks the majority of physicians are either unaware of hyperalgesia or unconvinced of its importance.

Markers of inflammation in the blood might correlate with clinical signs of hyperalgesia or declining pain thresholds on sensory tests.

Not exact matches

For some, this lack of evidence makes research into hyperalgesia look like a dead end.

«When I go to work every day, I don't think about opioid - induced hyperalgesia,» says Gary Bennett, a pain researcher at the University of California in San Diego.

His group found evidence in 91 patients tapering off opioids that those whose doses were higher at the start, forcing them to make greater reductions over the 3 - week program, had worse measures of heat pain hyperalgesia.

Some people also get opioid - induced hyperalgesia — opioids ramp up their pain instead of knocking it down.

There are already well established databases within the consortium, the London Pain Database (LPD) and QUAST (DFNS, Germany): The LPD is used for datamining of functional genomics data to help identify individual genes and functional networks associated with chronic pain, QUAST on the other hand collects questionnaire data, clinical and neurophysiological findings and calculates valid clusters of phenotypes with different interaction patterns of sensory loss with and without different types of peripheral and central hyperalgesia based on QST (quantitative sensory testing) data.

In addition, chronic oral administration of gabapentin (from day 24 — day 44) also reversed paclitaxel - induced mechanical hyperalgesia when administered at 100mg / kg but not 50 mg / kg.

A combination of peppermint oil and caraway oil attenuates the post-inflammatory visceral hyperalgesia in a rat model.

[176] I accept the opinions of Dr. Purtzki that the plaintiff has evidence of allodynia and hyperalgesia and seems to experience non-painful stimuli as painful and mildly painful stimuli as more painful, as a generalization to the area of pain.