But compared to a homogeneous material like water or a magnet — or even a collection
of identical cells in a dish — cancer is a hot mess.
It reinforces the notion that tumors (and TNBC in particular) are not a homogeneous mass
of identical cells, but a collection of distinct sub-populations of cells evolving somewhat independently of one another.
A clone is a group
of identical cells that are derived from the same cell.
After five or six days, the embryo is composed of a cluster
of identical cells called a blastocyst.
Used as a counter electrode in a dye - sensitized solar cell, the material enabled the cell to convert power with up to 6.8 percent efficiency and more than doubled the performance
of an identical cell that instead used an expensive platinum wire counter electrode.
Not exact matches
I would seem to be
identical with the history
of the assemblage
of cells that includes my neurons; my action, in the same way, would seem to be
identical with everything that is happening in my body while I perform it.
I could go on and elaborate on a number
of other disciplines or facts that creationists have to pretend into oblivion to retain their faith, including the Ice Ages, cavemen and early hominids, much
of microbiology, paleontology and archeology, continental drift and plate tectonics, even large parts
of medical research (medical research on monkeys and mice only works because they share a common ancestor with us and therefore our fundamental
cell biology and basic body architecture is
identical to theirs).
Even large parts
of medical research would be rendered unusable but for the fact that monkeys and mice share a common ancestor with us and therefore our fundamental
cell biology and basic body architecture is
identical to theirs.
The maximum difference between load
cell output readings for repeated loadings under
identical loading and environmental conditions; the ability
of an instrument, system, or method to give
identical performance or results in successive instances.
In addition, there may be applications where the use
of one's own stem
cells are needed, even if stem
cells from an
identical twin are available.
While all
cells in a specific organism share the
identical DNA sequence, only a fraction
of those genes are activated in a given
cell type.
Several physical measurements, including electron microscopy, assured us that our product was a closed loop coiled tightly around the virus - DNA template and that it was
identical in size and other details with the replicative form
of DNA that appears in the infected
cells.
The shape and chemical composition
of these granules is
identical to organelles found in
cells called melanosomes; these being responsible for creating and storing the pigment melanin.
Importantly, these three developmental signatures were found in distinct genetic clones —
cells with
identical patterns
of genetic mutations —
of tumor
cells.
The researchers have shown that it is possible to produce chromosome modifications in human
cells that are genetically
identical to those observed in leukemia and other types
of human cancer.
The researchers believe the hammerhead shark reproduced by a type
of asexual reproduction called automictic parthenogenesis, whereby an unfertilised egg is activated to behave as a normal fertilised egg by a small, nearly genetically
identical cell known as the sister polar body.
The case presented in the latest paper, published in the journal Stem
Cell Reports, suggests that uneven growth
of identical twins could start during the early stages
of preimplantation development.
Smell neurons begin as
identical precursor
cells, immature
cells that have not yet «decided» which type
of nerve
cell they will become.
One plausible explanation was that over the course
of successive population crashes, the devils had become so inbred that their
cells look
identical — at least to the animals» immune systems.
Bacteria expressing enzyme in one
cell (bright green), while genetically
identical cells do not, remaining protected from antibiotic onslaught; image courtesy
of Yuichi Wakamoto / Neeraj Dhar / John McKinney Some strains
of nasty bacterial infections, such as MRSA (methicillin - resistant Staphylococcus aureus), come loaded with resistance to antibiotics built right into their genes.
In 1957, developmental biologists first discovered that they could insert the nucleus
of adult frog
cells into frog eggs and create dozens
of genetically
identical tadpoles.
«If you looked at a liver
cell from my body and a neuronal
cell from my brain, the DNA would be
identical, but the
cells themselves would be very different because they are composed
of different proteins.
Proper control
of the
cell cycle is necessary to ensure that the resulting daughter
cells inherit
identical copies
of the DNA.
When a T
cell detects one, it morphs into a fighting machine, zapping invaders with lethal chemicals, multiplying into an army
of identical killers or signaling other immune - system troops to join the attack.
DNA sequences were once thought to be
identical from
cell to
cell, but it's increasingly understood that mutations can arise during brain development that affect only certain groups
of brain
cells.
The development
of each motor neuron was hardwired; each
cell was always born in the same order and achieved the
identical shape.
Because the
cells used to seed the platform can come from anyone, the new tissues could be genetically
identical to the intended host, reducing the risk
of organ rejection.
In the new study, Mikhail Pogorelyy and colleagues from the Ecole normale supérieure in Paris, and the Shemyakin - Ovchinnikov Institute
of Bioorganic Chemistry, Moscow, address this excess
of T -
cell clone sharing between genetically
identical twins.
The team used a statistical model
of T
cell receptor formation to analyze receptor DNA sequences in blood samples from adult pairs
of identical twins.
They first transplanted undifferentiated iPS
cells into the leg muscles
of genetically
identical recipient mice.
Cloning may eventually give us basically
identical genetic copies
of extinct species, but we'll be restricted to animals that went extinct more recently and have well - preserved
cells with intact nuclei.
The amount
of gas from an
identical wet
cell over the same period was 5842 cubic metres — more than eleven times as much.
An embryo starts out as a tiny clump
of identical stem
cells.
They used the gene editing technology CRISPR to engineer a series
of human embryonic stem
cell lines, which were
identical apart from the number
of DNA repeats that occurred at the ends
of their HTT genes.
He and his collaborators found that three transcription factors, when targeted to the pancreas
of a living mouse, converted fully formed, non-insulin-producing pancreatic
cells into
cells that were functionally
identical to insulin - producing
cells — no stem
cells required.
The result would not be a clone because
of the way
cells divide during sexual reproduction — the fertilised egg would not be genetically
identical to the original iPS
cells — but it would be something very strange and dangerous.
Even though 24 per cent
of the genes» DNA had changed, the proteins the
cells produced seemed
identical to the originals (Science, doi.org/pb9).
When he injected mice with embryonic stem
cells genetically
identical to the mice's own tissues, the new
cells thrived, growing into a large clump
of adult tissues.
About half
of melanoma patients harbor an
identical tumor - specific mutation in the BRAF gene, which encodes a protein kinase that helps drive
cell growth.
In the current paper, knowing that MYC, a transcription factor that binds the genome through sites that are
identical to the binding sites
of BMAL1, the team hypothesized that aberrant MYC expression perturbs the clock by deregulating components
of the circadian network in cancer
cells.
«We have found that the individual
cells within melanoma tumors are not all
identical, and tumors contain a sub-population
of cells that are inherently drug resistant, which accounts for the fact that advanced melanoma tumors return no matter how much the tumor is depleted,» said Meenhard Herlyn, D.V.M., D.Sc., professor and director
of Wistar's Melanoma Research Center.
They found that here too, the effects
of aneuploidy were varied across otherwise
identical cells.
This is the first direct evidence that
cells indeed have an ability to distinguish
identical copies
of chromosomes and separate them in a regulated manner.
That single
cell contains all the genetic information needed to develop into a human, and passes
identical copies
of that information to each new
cell as it divides into the many diverse types
of cells that make up a complex organism like a human being.
If each
cell is genetically
identical, however, how does it grow to be a skin, blood, nerve, bone or other type
of cell?
The first primate clones made by somatic
cell nuclear transfer are two genetically
identical long - tailed macaques born recently at the Chinese Academy
of Sciences Institute
of Neuroscience in Shanghai.
One
of the central mysteries
of biology is why the genome is largely
identical from
cell to
cell, even though
cells do different things.
The structure and composition
of the erionite from both regions is practically
identical, and samples from each place cause mesothelioma - associated changes and inflammation in
cell culture and mouse lungs.
«Only a subset produces IL - 17A upon skin injury, although the surface markers on these
cells seem
identical to those
of other DETCs,» MacLeod said.
Josef Singer and Judith Fazekas, both lead authors
of the study, discovered that a receptor frequently found on human tumor
cells (epidermal growth factor receptor or EGFR) is nearly 100 percent
identical with the EGF receptor in dogs.