Sentences with phrase «of identified neurons»

Egg - laying behavior in Aplysia is mediated by a set of peptides, including egg - laying hormone (ELH), which are released by a cluster of identified neurons, the bag cells.

Not exact matches

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

In a new study published in Cell Reports, scientists at the Gladstone Institutes identified different types of neurons in a brain region called the reticular thalamus.

The goal of early SMA drug discovery programs has been to identify small molecules that induce the SMN gene to produce sufficient levels of protein to improve motor neuron functioning in affected patients.

In a study published in Neuron, an interdisciplinary team of University of Pennsylvania researchers has identified a new explanation for this phenomenon.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

Researchers have identified the neurons in monkeys that are dampened by scratching, a finding that could lead to new ways of alleviating itching in humans.

The ~ 200 GB of data for each brain was then analyzed with machine learning algorithms that identify individual neurons by type, according to parameters «learned» from human experts.

Within the hypothalamus, scientists have identified two key groups of neurons that regulate appetite, known as AgRP neurons and POMC neurons.

The learning is expressed in the intracellularly recorded activity of identified motor neurons mediating three different defensive behaviors: escape locomotion, inking, and siphon withdrawal.

In work published today in The Journal of Neuroscience, Li and his team identify a group of long - range neurons that extend from the central amygdala.

The researchers also identified the specific neuron responsible for detecting high pH. They did this by showing that when a specific sensing neuron, called the ASH neuron, was destroyed by laser microsurgery, the worms no longer avoided high pH. Going another step further, the researchers also identified some of the proteins involved in the response to high alkalinity, which make up a calcium channel.

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children — Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.

Duke University biologist Pelin Volkan and colleagues have identified a set of genetic control switches that interact early in a fly's development to generate dozens of types of olfactory neurons, specialized nerve cells for smell.

By tweaking different fly genes and counting how many neuron types were produced as the flies matured, the team identified a network of five genes that work together like coordinated control switches to guide the precursor cells» transformation to mature neurons.

Recently, Prof. Yoko Yazaki - Sugiyama and Dr. Shin Yanagihara from Okinawa Institute of Science and Technology Graduate University (OIST) have, for the first time, identified the neurons in the brain that are associated with the auditory memory of the father's song in zebra finches, which could lead to insight into human speech development.

Identifying changes in the mitochondrial DNA in PPN cholinergic neurons has the potential to allow the development of more effective treatments targeted to specific cell - types.

Red staining on a section through the forebrain of a mouse identifies the neurons that carry sensory information directly into primary areas.

The continuation of this line of research is opening new avenues to identify what specific signals are used to promote this increased neurogenic response, with views focused in targeting neurogenesis as a therapeutic approach to promote the regeneration of lost neurons.»

«These three findings identify for the first the neurons and connections that underlie the Gate Control Theory of pain,» sums up Zeilhofer.

Using machine learning algorithms, they identified which parts of the data seemed to be the timing control signal between the prefrontal cortex and the amygdala and zeroed in on the individual neurons involved in that circuit.

In a paper published June 11 in the early - online edition of Neuron, researchers at the Buck Institute for Research on Aging and the University of California, Berkeley have identified a serotonin receptor, HTR7, as a key mediator of eczema and other forms of itch.

We obtained intracelllular recordings from identified gill motor neurons in the abdominal ganglionz of a semi-intact preparation of Aplysia wlhile we simultaneously recorded behavior responises of the gill.

Described in the January 7th issue of Neuron, the technique uses «deep,» highly sensitive whole - genome sequencing of single neurons and a new technology that identifies inserted bits of DNA caused by retrotransposons, one of several kinds of so - called somatic mutations that can arise as the brain develops.

By obtaining simultaneous intracellular recordings from both the sensory neurons and one of the main identified motor neurons, we have been able to reduce the reflex to its monosynaptic components.

In a paper published in the journal Neuron, researchers at Beth Israel Deaconess Medical Center (BIDMC) identified specific neural circuitry responsible for rousing the brain of mice in simulated apnea conditions.

Using the firing patterns of just five of any patient's neurons, the system identified the person as a responder or nonresponder with 92 percent accuracy.

Belgian researchers have identified a new strategy for treating an inherited form of dementia after attempting to turn stem cells derived from patients into the neurons most affected by the disease.

Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

Previous studies have identified neurons that only fire up when an animal points its head in a certain direction — some for east, others for south, for example — but reports of neurons that respond to changes in an animal's speed are sparse and largely anecdotal, says Jeffrey Taube, a neuroscientist at Dartmouth College who was not involved in the work.

In order to identify genes specific for the sensory neurons of Aplysia, a miniaturized differential screening method based on the polymerase chain reaction and applicable to small amounts of tissue was used.

Their end goal is to identify specific populations of neurons in the fruit fly brain that are necessary for emotion primitives — and whether these functions are conserved in higher organisms, such as mice or even humans.

But while the areas of the brain involved in estimating spatial orientation have been identified for some time, until now, no one has been able to either show that distinct neurons signaling «sensory conflicts» existed, nor demonstrate exactly how they work.

His laboratory implicated endocannabinoids in axon guidance and identified the molecular substrates of Δ9 - tetrahydrocannabinol action in developing neurons.

With simultaneous anatomical stainings they also identified which of these neurons sent their projections to the more remote secondary somatosensory area and the motor cortex, respectively.

Even before the recent genome work, researchers had characterized some of the components of black widow venom, identifying two seemingly unique families of proteins: latrotoxins, which act on neurons; and latrodectins, whose role in venom remains unclear.

Now that the biologists had identified one site — out of many — housing neurons that activated selectively for social encounters, they listened in on the goings - on by placing very fine electrodes in proximity.

«Since researchers can often identify several object - selective neurons within a single patient, multiple novel pairings of objects can be studied,» author Dr. Andrey Vyshedskiy explains.

The group has already identified several candidate molecules which activate GDNF receptors in immortalized cells and shown that one of them promoted survival of dopamineric neurons in vitro.

University of Queensland researchers have identified a potential treatment to delay motor neuron loss and symptoms in the inevitably fatal motor neuron disease (MND).

Blue corresponds to cell nuclei, and green to fluorescence emitted by a green - fluorescent protein that identifies neurons having received the virus that can genetically abolish the expression of lipoprotein lipase protein.

«While the genetic cause of this devastating disease has been identified, our study describes how mitochondrial dysfunction might contribute to motor neuron destruction even before the onset of symptoms,» said Ma.

In this study, Xu and colleagues identified a neural circuit where a group of serotonin neurons project to and activate dopamine neurons.

The findings, published in the Proceedings of the National Academy of Sciences Early Edition this week, identify a switch that occurs in neurons within the hypothalamus.

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy - induced neuropathy and HIV.

In the featured article published online on April 5 in Neuron, the researchers also conclude that potential treatments targeting the transport disruptions they identified in Huntington's disease neurons may also work for other neurodegenerative diseases, such as ALS and forms of dementia.

A specific kind of neuron found only in male mice and that detects a pheromone in female urine has been identified by researchers at Washington University School of Medicine in St. Louis.

They have identified the group of neurons in the brain that determines how a mouse responds to stress — whether with resilience or defeat.

Why the disease has such a wide range of effects isn't completely understood, but in recent years a potential cause — the loss of hormone - producing neurons, possibly through an autoimmune response — has been identified.

To start, the scientists examined previous experiments and identified several transcription factors — managerial proteins that switch on the activity of large sets of genes — that seemed crucial to the ability of immature neurons to develop into adult sensory neurons.