Sentences with phrase «of immune homeostasis»

CD4 + regulatory T (Treg) cells expressing the forkhead box transcription factor Foxp3 have a vital function in the maintenance of immune homeostasis and the prevention of fatal multi-organ autoimmunity throughout life.

Tolerance induction in the periphery is believed to be critical for the prevention of autoimmunity and maintenance of immune homeostasis.

Not exact matches

Now, the Laboratory of Malaria Immunology Team at the Immunology Frontier Research Center (IFReC), Osaka University, headed by Professor Cevayir COBAN, have used mouse malaria models to show that robust immune activation and invasion of parasite by - products into the bone marrow during and after malaria infection leads to an adverse balance in bone homeostasis - a process usually tightly controlled - by bone forming osteoblasts and bone resorbing osteoclasts.

While humanized mouse models for HIV infection have utility, the model is limited due to incomplete immune reconstitution, development of xenogeneic graft versus host disease (GVHD), and the absence of normal T cell homeostasis.

Taken together, these results demonstrate that the Emk protein kinase is essential for maintaining immune system homeostasis and that loss of Emk may contribute to autoimmune disease in mammals.

Hyper - costimulation through 4 - 1BB distorts homeostasis of immune cells.

It was shown that VPA could induce the apoptosis of activated T cells and maintain immune homeostasis through the caspase - 8 / caspase - 3 pathway (28).

We then examined whether VPA regulated immune homeostasis and ameliorated GVHD through inducing apoptosis of CD4 + T cells in vivo.

Dr. Kim is particularly interested in glutamate homeostasis and the interplay between neural and immune mechanisms of drug dependence and relapse.

Considering the importance of pDCs in the pathogenesis of SSc and other diseases characterized by a type I IFN signature, miR - 618 potentially represents an important epigenetic target to regulate immune system homeostasis in these conditions.

Additionally, deregulation of immune function, insulin resistance, cardiovascular, and gastrointestinal disorders, as well as other pathological processes induced by chronic stress may also profoundly affect brain homeostasis.»

Research reveals the mosaic of autoimmune diseases linked to stress and natural solutions to restore immune homeostasis

When called to arms due to injury, infection or disruption in homeostasis, these minuscule cells mobilize and transform into debris digesting cells capable of sounding the alarm to draw more immune cells to the afflicted site.

Most people think that you have to apply something topically in order to effect the skin, but numerous articles discuss the importance of oral probiotic consumption and reduce skin related inflammation, reinforces skin barrier function, decreases skin sensitivity and modulates the skin immune system leading to the preservation of skin homeostasis.

[3] Hill, D. A., et al. «Intestinal bacteria and the regulation of immune cell homeostasis.»

«CBD interacts with the body through the endogenous cannabinoid system (ECS) which is the part of the body that regulates the body's homeostasis or general state of balance, which impacts integral functions of the body such as mood, sleep, hormone regulation and pain / immune response,» says Madeleine Murphy, whose Brooklyn cafe sells a CBD - infused hot chocolate.