Sentences with phrase «of immune modulation»
Ten U.S. patents issued or pending include Dr. Prendergast as an inventor in this important new arena of immune modulation emerging as pivotal in human cancer, autoimmunity, chronic viral infection and other chronic inflammatory conditions.
http://www.kimmelcancercenter.org/ Not exact matches
Specifically, researchers found that modulation of B lymphocyte function may be a means of regulating T lymphocyte function to treat immune - mediated disorders, including inflammatory bowel diseases (IBD).
«Modulation of PPAR - γ and GLUT - 1 levels may boost the immune system to fight infection,» said principal investigator Prasadarao V. Nemani, PhD of CHLA and the Keck School of Medicine of the University of Southern California.
Researchers are currently investigating other ways to produce the same modulation of the immune response because the access of IVIg to the brain when administered peripherally is very limited.
While many types of immune cells are involved in obesity - induced inflammation, «NK cell modulations do not change any of the other immune cells,» Lee says.
Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during ¿ - herpesviral infection.
Effects of Rubus coreanus byproducts on intestinal microbiota and the immune modulation — Da Yoon Yu — Asian - Australasian Journal of Animal Sciences (AJAS)
Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during gammaherpesvirus infection.
Computer - guided design of optimal microbial consortia for immune system modulation — Richard R Stein — eLife
Thus it is likely that evasion of alloreactivity is a result of both MSC hypoimmunogenicity, modulation of T cell immune induction and the creation of a suppressive milieu around MSC.
Modulation of tumor antigen expression, particularly MHC class I and II is a particularly common component of tumor immune evasion 183.
Newer CXCR4 antagonists are under clinical evaluation for therapeutic intervention in various cancers, hematologic and vascular disorders, HIV infection, and other immune system disorders involving the modulation of the SDF - 1 / CXCR4 axis, such as rheumatoid arthritis and lupus [54 - 56].
The drug candidate is a synthetic, small molecule inhibitor of indoleamine 2,3 - dioxygenase (IDO1) that also inhibits IDO1 in the tumor micro-environment to trigger immune - modulation.
IDO1 Inhibitor (EOS200271): Synthetic, small molecule inhibitor of indoleamine 2,3 - dioxygenase (IDO1) to trigger immune - modulation in the tumor micro-environment.
Modulation of apoptosis and immune signaling pathways by the Hantaan virus nucleocapsid protein.
These results raise the hope that immune modulation may be enlisted in the treatment of this deadly disease.
Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with allergen - specific modulation of immune reactivity.
Reduced levels of secreted IL - 22 in heterogeneous lymphocyte mixtures of Rag1 - / - splenocytes could be due to another cell affecting ILC3 production of IL - 22 and / or modulation in IL - 22 from other innate immune cells that have been reported to produce low levels of IL - 22, such as DCs or neutrophils [22, 42, 43].
Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels
There were many decades of challenge to prove that modulation of the immune system is a standard and impactful way to treat cancer.
IDO1 has been implicated in immune modulation through its ability to limit T cell function and engage mechanisms of immune tolerance, and as such preventing tumor rejection.
Research is already underway at City of Hope to unlock the immune system's role in diabetes, including T cell modulation and stem cell - based therapies that may reverse the autoimmune attack on islet cells in the pancreas, which is the cause of T1D.
And then we can have a lot of benefits with immune modulation.
Some pioneering work has also been done with immune modulation through a low dose prescription of naltrexone.
These microscopic little beings are responsible for the health of our intestinal lining, and the modulation of our immune system.
Outside the brain, the endocannabinoid system has been found to be activated in virtually every physiological system researchers have investigated, playing a critical role in the modulation of the autonomic nervous system, the immune system, reproductive and gastrointestinal tracts, sympathetic ganglia, arteries, lung, heart and endocrine glands.
In fact, modulations of the immune system using pharmaceutical drugs such as different injectable interferon beta formulations and corticosteroids are the most widely used therapies that are prescribed for patients with relapsing - remitting multiple sclerosis.
You can read more about using natural compounds for modulations and re-balancing of the immune system here
Studies to date have demonstrated that phytochemicals in common fruit and vegetables can have complementary and overlapping mechanisms of action, including modulation of detoxification enzymes, scavenging of oxidative agents, stimulation of the immune system, regulation of gene expression in cell proliferation and apoptosis, hormone metabolism, and antibacterial and antiviral effects (15, 16).
I've come to consider the gut biota as possibly THE main force in body composition and metabolism... they control a LOT of what's going on in us, whether through FIAF or neurotransmitters or immune modulation or who knows what else, and it is our chronic food habits that in the end dictate what kind of biota we maintain.
Immune modulation is the third type of approach to Hashimoto's... chemicals, nutrients, herbs medications and even our thoughts can modulate our immune system.
Immune System Modulation: Many cancers and many cancer treatments cause a suppression of the bone marrow, the source of blood cells that are the army of the immune system.
This, in turn, sets the stage for the development of autoimmune diseases like rheumatoid arthritis or lupus, 2 Cordain, L., Toohey, L., Smith, MJ., et al. «Modulation of immune function by dietary lectins in rheumatoid arthritis,» The British Journal of... continue and creates chronic inflammation throughout your body.
Cordain, L., Toohey, L., Smith, MJ., et al. «Modulation of immune function by dietary lectins in rheumatoid arthritis,»
A hormone that plays an extremely important role in the modulation, or balancing, of the immune system.
Provides immune modulation for the prevention and treatment of infections, allergies and asthma
She lectures all over the world and trains physicians in integrative therapies including the application of mistletoe therapy, and consults with researchers on projects involving immune modulation via mistletoe, hyperthermia and the ketogenic diet.
L - arginine is a semi-essential amino acid involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation.
There is a new approach in treating the Hashimoto's disease as an autoimmune condition using the modulation of the immune system.
There are recent indications that the regular consumption of certain subclasses of highly fermentable dietary fibre sources result in gut associated immune and flora modulation as well as a significant production of short chain fatty acids.
Beta carotene and selenium deficiencies, two of the most common nutrient deficiencies, are important due to their dual function as nutrients necessary for immune modulation and as antioxidants.
Examples include: alterations in brain electrical and metabolic activity, activation of internal opioids, changes in neuronal excitability and neurotransmitter release, immune effects, hormonal shifts, and stress modulation.
Licastro, F., Mocchegiani, E., Masi, M., and Fabris, N. Modulation of the neuroendocrine system and immune functions by zinc supplementation in children with Down's syndrome.
Taurine is a sulfur - containing amino acid that is involved in a diverse array of biological and physiological functions, including bile salt conjugation, body fluid regulation, calcium modulation, anti-oxidation, and immune system regulation.
The physiologic effects of Hyperbaric Oxygen Therapy («HBOT») include improved oxygenation, intravascular and tissue gas bubble reduction, vasoconstriction, increased antimicrobial activity, modulation of inflammation, improved immune function, and angiogenesis.
This academic and scientific program develops uniquely trained scientists who are able to contribute to the improved health of food - producing, companion, and aquatic animals through vaccine development and modulation of the immune response.
Probiotic lactobacilli are believed to improve urogenital health in women through immune modulation, pathogen displacement, and creation of a niche less favorable for pathogenic bacterial proliferation.