Sentences with phrase «of immune suppression»

This work builds on previous studies by the Miller lab in dissecting previously unknown mechanisms of immune suppression in pancreatic cancer with the goal of developing new immunotherapies.

Meanwhile, Van den Eynde and his team are already hard at work looking for the other novel mechanisms of immune suppression in their model.

(We rarely use this because there is a very small risk of immune suppression using prescription hydrocortisone.

This state of immune suppression may leave patients unable to fight off secondary infections, such as pneumonia associated with being on a ventilator.

(I rarely use this because there is a very small risk of immune suppression using prescription hydrocortisone.

The gene signature identified by Hancock and his colleagues relates to a special type of immune suppression called cellular reprogramming and suggests that treating inflammation in sepsis is a bad idea.

Johns Hopkins and other cancer researchers report that a very short course of a chemotherapy drug, called cyclophosphamide, not only can prevent a life - threatening immune response in some bone marrow transplant recipients, but also can eliminate such patients» need for the usual six months of immune suppression medicines commonly prescribed to prevent severe forms of this immune response.

Researchers have had some success in transplanting islet cells, but recipients require heavy doses of immune suppression.

«This is an indicator of the degree of immune suppression in septic patients, and it tells us they are highly immune - suppressed,» explained senior author Richard S. Hotchkiss, MD, professor of anesthesiology.

But he says that the results are «highly suggestive» that measles is contributing to this longer period of immune suppression.

iTeos» pipeline addresses key unmet needs in immuno - oncology: the inhibition of immune suppression in inflamed (hot) tumors and the increase of immunogenicity in non-inflamed (cold) tumors.

The VC - 01 product candidate is being developed as a potential long - term diabetes treatment with the goals of no immune suppression required, and a reduced risk of hypoglycemia and diabetes - related complications.

Our understanding of the basis of immune suppression is evolving, but we know that it involves the production of the chemokine, CXCL12, by the fibroblastic stromal cells, binding of this CXCL12 by pancreatic cancer cells, and exclusion of T cells from the vicinity of the cancer cells.

Intriguingly, we also found that rare individuals moved out of the IRP category by a process of immune suppression, including increases in IL - 6 and IL - 10 and decreases in the number of CD3 + CD8 + CD28 - cells.

Some sort of immune suppression appears to be a pre-requisite to infection for both mites (as is the case with dogs).

Regional results of a new survey show U.S. dairy producers are acutely aware of the consequences of immune suppression, and 59 percent of survey respondents rate mastitis as the top complication of compromised immunity.

«A controversy has existed over whether patients with sepsis progress to a state of immune suppression,» said co-senior author Gregory Storch, MD, a virologist and chief of the Division of Pediatric Infectious Diseases.

Dr. Matsuzaki has accumulated extensive expertise in T - cell biology and mechanisms of immune suppression in periphery and tumor microenvironments in patients with ovarian cancer.

The use of immune suppression in the treatment of autoimmune disorders and other diseases needs to be better individualised to prevent undue impairment of lung defences and severe secondary infections.