Sentences with phrase «of immuno»

The application of immuno - assays for serological detection of morbillivirus exposure in free ranging harbor seals (Phoca vitulina) and sea otters (Enhydra lutris) from the western coast of the United States.

Andrew Burbidge: We have looked in Australia at biological control of foxes and rabbits and house mice at various times, particularly in the late»80s and»90s, there was work done within CSIRO, funded by the federal government, to see whether you could develop the idea of immuno - contraception.

This occurs when the virus becomes're - activated» and the cat shows signs of immuno - suppression and suffers from repeated infections.

First is her observation that the protein quality of food, especially the presence of immuno - reactive proteins, is extremely important for health.

While our primary focus is on the development of immuno - oncology therapies, we also establish collaborative partnerships to develop potential treatments for non-oncology diseases, such as infectious and allergic diseases.

SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.

The portfolio includes the next generation of therapies that will unleash the full potential of immuno - oncology, both in inflamed and non-inflamed cancers.

The month - long campaign celebrates achievements in the field of immuno - oncology, with fundraising and awareness - building programs for cancer immunotherapy research.

First - of - its - kind analysis of the global immuno - oncology clinical landscape from pre-clinical development to regulatory approval provides unprecedented opportunity to advance the field of immuno - oncology to improve patient care.

A number of immuno - therapeutic methods have demonstrated promising clinical value.

During the last three years, iTeos has developed a comprehensive portfolio of immuno - oncology drug candidates and these additional funds will enhance our capability to demonstrate the potential clinical benefits of our products.

Pedro de Noronha Pissarra, chief executive officer of Biotecnol said: «We're very proud to work with Cancer Research UK on the development of advanced clinical trial approaches in this competitive and highly promising field of immuno - oncology.

A number of immuno - oncology therapies on the horizon tackle this problem in novel ways.

More precise application of immuno - therapies and the development of new approaches requires knowing the detailed immune landscape of individual patients and tumors.

Not exact matches

These products — largely innovative and pricey specialty medications that include breakthrough Hepatitis C treatments and immuno - oncology drugs — reflect the increased productivity and improved pipelines of pharma's R&D departments in recent years.

Bristol's $ 2.4 billion purchase of Medarex — which pharmaceutical analysts routinely cite as one of the best acquisitions in the history of the industry — would give the company not only a new blockbuster but also a leadership position in a burgeoning drug category: immuno - oncology.

FLX Bio, Inc. is a privately - held biopharmaceutical company focused on the discovery, development and commercialization of novel immuno - oncology agents.

The adjusted tally beat consensus expectations of $ 1.00, thanks in part to stronger demand for its standout immuno - oncology drug KEYTRUDA, and management responded by raising its full - year guidance.

Julia has also mapped competitive landscapes with a focus on immuno - oncology and melanoma as a member of the Oncology Team within the TechAtlas division of RA Capital.

ZURICH (Reuters)- Roche's Tecentriq immuno - oncology drug failed a late - stage follow - up trial against advanced bladder cancer, the Swiss drugmaker said on Wednesday, raising questions about whether regulators could scale back their approval of the medicine.

They say they expect next year to start up to 20 patient testing programs of such immuno - oncology drugs.

Albert Bourla, head of Pfizer's cancer business, said «immuno - oncology is a top priority for Pfizer.»

IDEAYA Biosciences, Inc., an oncology - focused biotechnology company committed to the discovery of breakthrough synthetic lethality medicines and immuno - oncology therapies, announced today the successful completion of a $ 94 million crossover Series B financing.

IDEAYA is pioneering the next generation of biomarker - enabled synthetic lethality therapies for genetically defined patient populations and advancing an immuno - oncology pipeline targeting immuno - metabolism and innate immunity.

«We are pleased to share this vision with the unique blend of crossover funds, pharmaceutical companies, and venture capital investors participating in our Series B, and look forward to advancing our position as the leading biotech with a dual focus on synthetic lethality and immuno - oncology.»

Predicine has launched a new liquid biopsy panel called PredicineATLAS, which covers 600 genes and offers a readout of patients tumor mutational burden to help inform and assess immuno - oncology treatment.

Investigators have repeatedly touted the drug as a potential lynchpin in immuno - oncology, focusing on an enzyme that suppresses the immune cells Opdivo and a whole new class of PD - 1 / L1 checkpoints are designed to unleash in an attack on cancer cells.

He also served as Global Head of the Immuno - Oncology Translational Innovation Platform where he was instrumental in rebuilding immuno - oncology (IO) research at the company, including pruning and re-orienting the discovery pipeline.

Biotech Round - Up: M&A s, Financings and Immuno - Oncology Source: John McCamant for Streetwise Reports (4/18/18) John McCamant, editor of Medical Technology Stock Letter, reviews biotech M&A and financings, and discusses one company that is expanding its immuno - oncology pipeline.

For example, we've seen new discoveries in health care recently, especially in immuno - oncology therapies, which help the immune systems of cancer patients recognize and destroy cancerous cells.

TCGA data, which has been the foundation of many immuno - oncology hypotheses and discoveries, will still be available for research.

«There are authentic dietary supplements — multivitamins, calcium, iron — which do supplement the diet» and can help many people, says rheumatologist and immuno - logist Donald Marcus of Baylor College of Medicine in Houston, Texas, an early critic of the supplement industry.

They did it by delivering immuno - modulatory compounds — specifically, the bioactive protein interleukin - 10 — into the inflamed intestine, which reduced both the speed and severity of polyp formation.

The researchers suggest that their blood test serves as a cheap and simple option to pre-select individuals from the general population for further testing by these more invasive and costly methods to exclude the falsely positive subjects.The blood test developed by Gerwert and colleagues uses a technology called immuno - infrared sensor to measure distribution of pathological and healthy structures of amyloid - beta.

«Our work could also contribute to ongoing efforts in immuno - oncology and the treatment of cancer,» explained Tao Xu, postdoctoral scholar in Ding's laboratory and first author of the study.

«Our findings could have a significant impact on the treatment of autoimmune diseases, as well as on stem cell and immuno - oncology therapies,» said Gladstone Senior Investigator Sheng Ding, PhD, who is also a professor of pharmaceutical chemistry at the University of California, San Francisco.

«The treatment of multiple myeloma has improved significantly in recent years with the introduction of therapies such as proteasome inhibitors [which interfere with tumor cells» protein - disposal system] and potent immuno - modulatory agents,» said the paper's senior author and lead investigator, Paul Richardson, MD, clinical program leader and director of clinical research at Dana - Farber's Jerome Lipper Multiple Myeloma Center, and the R.J. Corman professor at Harvard Medical School.

Grape - like structures of viral replication territories in the nucleus of a human cell visualized by click - chemistry and immuno - fluorescence confocal microscopy.

«Understanding how cancers suppress the immune system is the key to identifying more effective immuno - therapies,» said Brent Hanks, M.D., Ph.D., at Duke and senior author of the study.

Probiotic Lactobacillus casei Zhang (LCZ) alleviates respiratory, gastrointestinal & RBC abnormality via immuno - modulatory, anti-inflammatory & anti-oxidative actions — Yan - Yan Hor — Journal of Functional Foods

Seres Therapeutics, Inc. (NASDAQ: MCRB) today announced that new preclinical data supporting the development of microbiome therapeutics for immuno - oncology (leveraging gut microbiota to impact tumor immunotherapy) 1 will be presented today by Sceneay et al in the late breaking poster session at the 2018 American Association for Cancer Research Annual Meeting (AACR) in Chicago.

Alongside his CEO role at Hookipa, Joern is Chairman of Molecular Partners AG and a Board member of Unum Therapeutics, both of which are developing next - gen immuno - oncology therapies.

Cytogenetic and immuno - FISH analysis of the 4q subtelomeric region, which is associated with facioscapulohumeral muscular dystrophy.

Moderna initiated a Phase 1 study of mRNA - 2416, an intratumoral (iTu) immuno - oncology (I - O) therapeutic that encodes for the membrane expression of the co-stimulatory protein OX40 Ligand, or OX40L, to potentially enhance T - cell attack against tumors.

The project associates the expertise of IRIBHM in GPCR discovery and validation, the unique technology on sensory GPCRs developed by ChemCom, the in - depth tumor immunology expertise of de Duve with the drug discovery capabilities of iTeos and the expertise of ImmunXperts with human primary cells in immuno - oncology.

Under the terms of the new agreement, AstraZeneca and Moderna, a pioneer of mRNA Therapeutics ™, have agreed to collaborate on two specific immuno - oncology programs, based on promising pre-clinical data, including pharmacology in tumor models.

The company showed how they first defined A2A as the receptor required for mediating the effect of adenosine on immune cells within the tumor microenvironment and reported the characterization of a novel immuno - oncology - dedicated adenosine receptor 2A antagonist that functions in the high adenosine concentration found in tumors.

The immuno - oncology revolution has spurred a renewed interest in T cell biology, including therapeutic use of T cells themselves.

iTeos» pipeline addresses key unmet needs in immuno - oncology: the inhibition of immune suppression in inflamed (hot) tumors and the increase of immunogenicity in non-inflamed (cold) tumors.

Topics range from toll - like receptors and composite limb grafts to recent immuno - suppression trials and issues in the globalization of transplantation.